SWE101 |
| رقم الكتالوجGC61309 |
SWE101 (المركب 22 ب) هو مثبط قوي للإيبوكسيد هيدرولاز (sEH) -P قابل للذوبان مع IC50s من 4 ميكرومتر و 2.8 ميكرومتر للإنسان والفئران sEH-P ، على التوالي
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Cas No.: 2376322-12-0
Sample solution is provided at 25 µL, 10mM.
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SWE101 (compound 22 b) is a potent soluble epoxide hydrolase (sEH)-P inhibitor with IC50s of 4 μM and 2.8 μM for human and rat sEH-P, respectively. SWE101 does not inhibit neither hydrolase nor phosphatase activity of the mouse sEH[1].
[1]. Kramer JS, et al. Discovery of first in vivo active inhibitors of soluble epoxide hydrolase (sEH) phosphatase domain. J Med Chem. 2019 Aug 22.
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