α1- and α2B-adrenoceptor antagonist (Ki values are 3.3, 0.7, 1.1, 7.7, 1510 and 78.2 nM for α1A, α1B, α1D, α2B, α2A and α2C receptors respectively). Antihypertensive following oral or intravenous administration in vivo.
Kyncl (1986) Pharmacology of tera. Am.J.Med. 80 12 PMID:2872801 |Hancock et al (1995) Actions of tera. and its enantiomers at subtypes of α1- and α2-adrenoceptors in vitro. J.Recept.Signal Transduct.Res. 15 863 PMID:8673721 |Maruyama et al (1994) Comparison of displacemental potencies of tera. enantiomers for α1-adrenoceptor subtypes. Biol.Pharm.Bull. 17 1126 PMID:7820122