الصفحة الرئيسية>>Signaling Pathways>> TGF-β / Smad Signaling>>Trabedersen

Trabedersen (Synonyms: AP 12009)

رقم الكتالوجGC70050 Copy One-Click Copy Product Info

ترابيديرسن (AP 12009) هو نوع من الحمض النووي المفقود للأكسجين والذي يمكنه تثبيط TGF-β2 (TGF-beta/Smad) بشكل محدد. يمكن استخدام ترابيديرسن في دراسة أورام المخ الخبيثة وغيرها من الأورام التي تفرز TGF-β2 بشكل زائد، مثل أورام الجلد والبنكرياس والقولون.

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Trabedersen التركيب الكيميائي

Cas No.: 925681-61-4

الحجم السعر المخزون الكميّة
1mg
178٫00
متوفر
5mg
430٫00
متوفر

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مراجعات العميل

بناء على آراء العملاء.

Sample solution is provided at 25 µL, 10mM.



Chemical Properties of Trabedersen

Cas No. 925681-61-4 SDF
المرادفات AP 12009
Formula M.Wt 5768.7
الذوبان H2O : 100 mg/mL (17.33 mM; Need ultrasonic) Storage Store at -20°C, away from moisture
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Trabedersen

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 173.3 μL 866.7 μL 1.7335 mL
5 mM 34.7 μL 173.3 μL 346.7 μL
10 mM 17.3 μL 86.7 μL 173.3 μL
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In vivo Formulation Calculator (Clear solution) of Trabedersen

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Trabedersen

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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