Arginase

Human arginases I and II inhibitor

arginase inhibitor

nor-NOHA (acetate) is an arginase inhibitor. nor-NOHA inhibits arginase from hydrolyzing L-arginine to L-ornithine, regulates L-arginine metabolic flux, affects NO production and immune responses.

CB-1158 (INCB01158) (CB-1158) is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively. Immuno-oncology agent.

Piceatannol 3'-O-glucoside, an active component of Rhubarb, activates endothelial nitric oxide (NO) synthase through inhibition of arginase activity with IC50s of 11.22 ?M and 11.06 ?M against arginase I and arginase II, respectively.

BEC is a potent slow-binding competitive inhibitor of recombinant rat liver arginase I with Ki values of 0.4 and 0.6 μM from kinetic analyses.

Nor NOHA monoacetate, a synthetic chemical derivative of L-arginine, is a selective and reversible inhibitor of Arginase-1.

2-Aminoimidazole is a potent antibiofilm agent that can be used as an adjuvant to antimicrobial.

Numidargistat (CB-1158) dihydrochloride is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively. Immuno-oncology agent.

OATD-02 drochloride is the drochloride salt form of OATD-02.

Arginase inhibitor 2 hydrochloride is an Arginase inhibitor.