GLPBio

ASP 7663

Catalog No.: GC50115Purity:>99.00%
COASDSData Sheet
Selective TRPA1 activator

Products are for research use only. Not for human use. We do not sell to patients.

ASP 7663
Cas No.: 1190217-35-6
10mM (in 1mL DMSO)In Stock
$110.00
1
1mgIn Stock
$38.00
1
5mgIn Stock
$90.00
1
10mgIn Stock
$144.00
1
25mgIn Stock
$245.00
1
50mgIn Stock
$378.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

1 publicationsPublications from researchers using this product

Description

Selective TRPA1 activator (EC50 values are ~0.5 μM in human, mouse and rat). Displays little or no affinity at more than 60 other related receptors, channels and enzymes. Stimulates 5-HT release from QGP-1 cells. Exhibits an abdominal analgesic effect in vivo. Orally bioavailable.

Kojima et al (2014) Effects of novel TRPA1 receptor agonist ASP7663 in models of drug-induced constipation and visceral pain. Eur.J.Pharmacol. 723 288 PMID:24291101

Product Documents

Purity:>99.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1190217-35-6
SMILES
O=C2/C(C1=CC=CC(F)=C1N2CC(C)C)=C/C(O)=O
Molecular Formula
C14H14FNO3
Molecular Weight
263.26
Solubility
DMSO: 25 mg/ml,Ethanol: 25 mg/ml
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

Reviews

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