ASP 7663 |
| Catalog No.GC50115 |
Selective TRPA1 activator
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1190217-35-6
Sample solution is provided at 25 µL, 10mM.
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Selective TRPA1 activator (EC50 values are ~0.5 μM in human, mouse and rat). Displays little or no affinity at more than 60 other related receptors, channels and enzymes. Stimulates 5-HT release from QGP-1 cells. Exhibits an abdominal analgesic effect in vivo. Orally bioavailable.
Kojima et al (2014) Effects of novel TRPA1 receptor agonist ASP7663 in models of drug-induced constipation and visceral pain. Eur.J.Pharmacol. 723 288 PMID:24291101
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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