GLPBio

Autophagy-IN-8

Catalog No.: GC78988Purity:>97.50%
Autophagy-IN-8 is an autophagy inhibitor.

Products are for research use only. Not for human use. We do not sell to patients.


Autophagy-IN-8
Cas No.: 2027550-79-2
5mgIn Stock
$166.00
1
10mgIn Stock
$263.00
1
25mgIn Stock
$526.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

Autophagy-IN-8 is an autophagy inhibitor. Autophagy-IN-8 exhibits antiproliferative activity against cancer cells. Autophagy-IN-8 can be used in the research of melanoma and pancreatic cancer [1].

In Vitro, Autophagy-IN-8 (DQ 660) exhibits antiproliferative activity against cancer cells[1].

References:
[1]. Ravi K. AMARAVADI, et al. Dimeric quinacrine derivatives as autophagy inhibitors for cancer therapy. WO2016168721A1. 2017-10-17.

Product Documents

Purity:>97.50%Appearance:A solid

Chemical Properties

CAS No.
2027550-79-2
Molecular Formula
C40H45Cl2N5O2
Molecular Weight
698.72
Solubility
DMSO: 100 mg/mL (143.12 mM; Need ultrasonic)
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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