Axl
Axl is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm and takes part in the stimulation of cell proliferation.
Products Related to Axl(6)
- GC14214BMS-777607CAS: 1025720-94-8Purity: >99.00%
BMS-777607 is a pan-TAMkinase inhibitor with IC 50 values of 3.9Nm, 1.1nM, 1.8nM, and 4.3nM for Met, Axl, Ron, and Tyro3, respectively.
- GC15779Cabozantinib (XL184, BMS-907351)CAS: 849217-68-1Purity: >99.50%
Cabozantinib (XL184, BMS-907351) is an orally bioavailable and potent inhibitor of MET and VEGFR2 with IC 50 values of 1.3nM and 0.035nM, respectively.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC14214 | BMS-777607 | 1025720-94-8 | >99.00% | |
BMS-777607 is a pan-TAMkinase inhibitor with IC 50 values of 3.9Nm, 1.1nM, 1.8nM, and 4.3nM for Met, Axl, Ron, and Tyro3, respectively. | ||||
| GC15779 | Cabozantinib (XL184, BMS-907351) | 849217-68-1 | >99.50% | |
Cabozantinib (XL184, BMS-907351) is an orally bioavailable and potent inhibitor of MET and VEGFR2 with IC 50 values of 1.3nM and 0.035nM, respectively. | ||||
| GC17618 | R428 | 1037624-75-1 | >99.00% | |
R428, as a Axl inhibitor, blocks Axl autophosphorylation on its C-terminal docking site, Tyr821, at nanomolar concentrations[1]. | ||||
| GC14218 | TP-0903 | 1341200-45-0 | >99.50% | |
TP-0903 (TP-0903) is a potent and selective Axl receptor tyrosine kinase inhibitor with an IC50 value of 27 nM. | ||||
| GC14241 | LDC1267 | 1361030-48-9 | >98.00% | |
TAM kinase inhibitor,highly selective | ||||
| GC13500 | UNC2881 | 1493764-08-1 | >99.50% | |
Mer tyrosine kinase inhibitor | ||||