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Tyrosine Kinase

Products for  Tyrosine Kinase

  1. Cat.No. Product Name Information
  2. GC41183 α-Carotene

    all-trans-α-Carotene

    α-Carotene is a precursor of vitamin A that has been found in various fruits and vegetables.

    α-Carotene  Chemical Structure
  3. GC38006 β-Hydroxyisovalerylshikonin Beta-hydroxyisovalerylshikonin is a natural product isolated from Lithospermium radix, acts as a potent inhibitor of protein tyrosine kinases (PTK), with IC50s of 0.7μM and 1μM for EGFR and v-Src receptor, respectively. Beta-hydroxyisovalerylshikonin is effective against a wide variety of tumor cell lines, and most efficiently induces cell-death in NCI-H522 and DMS114 cells. β-Hydroxyisovalerylshikonin  Chemical Structure
  4. GC41653 (±)16(17)-DiHDPA (±)16(17)-DiHDPA is produced from cytochrome P450 epoxygenase action on docosahexaenoic acid. (±)16(17)-DiHDPA  Chemical Structure
  5. GC41656 (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol

    (±)214,15EG

    2-Arachidonoyl glycerol (2-AG) is an endogenous central cannabinoid (CB1) receptor agonist that is present at relatively high levels in the central nervous system. (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol  Chemical Structure
  6. GC13944 (5Z)-7-Oxozeaenol

    FR148083,L-783,279,LL-Z 1640-2

    TAK1 mitogen-activated protein kinase kinase kinase (MAPKKK) inhibitor

    (5Z)-7-Oxozeaenol  Chemical Structure
  7. GC17800 (E)-FeCP-oxindole VEGFR-2 inhibitor (E)-FeCP-oxindole  Chemical Structure
  8. GC61807 (E/Z)-AG490 (E/Z)-AG490 ((E/Z)-Tyrphostin AG490) is a racemic compound of (E)-AG490 and (Z)-AG490 isomers. (E)-AG490 is a tyrosine kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3. (E/Z)-AG490  Chemical Structure
  9. GC25000 (E/Z)-BCI

    BCI, NSC 150117

    (E/Z)-BCI (BCI, NSC 150117) is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6) and mitogen-activated protein kinase with EC50 of 13.3 μM and 8.0 μM for DUSP6 and DUSP1 in cells, respectively. (E)-BCI induces apoptosis via generation of reactive oxygen species (ROS) and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells. (E/Z)-BCI  Chemical Structure
  10. GC63864 (E/Z)-Zotiraciclib hydrochloride

    (E/Z)-TG02 hydrochloride; (E/Z)-SB1317 hydrochloride

    (E/Z)-Zotiraciclib ((E/Z)-TG02) hydrochloride is a potent CDK2, JAK2, and FLT3 inhibitor. (E/Z)-Zotiraciclib hydrochloride  Chemical Structure
  11. GC72195 (Pro3) GIP, human TFA (Pro3) GIP, human TFA is an efficacious, stable and specifichuman GIP receptor (hGIPR)full agonist. (Pro3) GIP, human TFA  Chemical Structure
  12. GC14729 (R)-Crizotinib

    PF 2341066

    A c-MET and ALK receptor tyrosine kinase inhibitor (R)-Crizotinib  Chemical Structure
  13. GC19012 (R)-GNE-140

    ?A TRK kinase (TKI) inhibitor

    (R)-GNE-140  Chemical Structure
  14. GC13136 (S)-Crizotinib Potent MTH1 inhibitor (S)-Crizotinib  Chemical Structure
  15. GC63797 (S)-Sunvozertinib

    (S)-DZD9008

    (S)-Sunvozertinib ((S)-DZD9008), the S-enantiomer of Sunvozertinib, shows inhibitory activity against EGFR exon 20 NPH and ASV insertions, EGFR L858R/T790M mutation and Her2 exon20 YVMA insertion (IC50=51.2 nM, 51.9 nM, 1 nM, and 21.2 nM, respectively). (S)-Sunvozertinib also inhibits BTK. (S)-Sunvozertinib  Chemical Structure
  16. GC13344 (Z)-FeCP-oxindole VEGFR-2 inhibitor (Z)-FeCP-oxindole  Chemical Structure
  17. GC62291 (Z)-Orantinib

    (Z)-SU6668; (Z)-TSU-68

    (Z)-Orantinib ((Z)-SU6668) is a potent, selective, orally active and ATP competitive inhibitor of Flk‐1/KDR, PDGFRβ, and FGFR1, with IC50s of 2.1, 0.008, and 1.2 ?M, respectively. (Z)-Orantinib is a potent antiangiogenic and antitumor agent that induces regression of established tumors. (Z)-Orantinib  Chemical Structure
  18. GC12172 1-Naphthyl PP1

    1NaphthylPP1, PP1 Analog

    Src family kinases inhibitor 1-Naphthyl PP1  Chemical Structure
  19. GC34119 1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) 1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases. 1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) inhibits v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively. 1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride)  Chemical Structure
  20. GC11696 1-NM-PP1

    PP1 Analog II

    Pp60c-src inhibitor 1-NM-PP1  Chemical Structure
  21. GC42026 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC

    1-Hexadecanoyl-sn-glycero-3-Phosphatidylcholine, 1-Hexadecanoyl-sn-glycero-3-Phosphocholine, 1-Hexadecanoyl-sn-glycerol-3-Phosphorylcholine, Lyso-PC, 1-Palmitoyl-sn-glycero-3-Phosphocholine, PC(16:0/0:0), 16:0/0:0-PC

    1-Palmitoyl-2-hydroxy-sn-glycero-3-PC is an abundant gonadal LPC (lysophosphatidylcholine). 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC  Chemical Structure
  22. GC35053 123C4 123C4 is a potent, selective and competitive agonist of the receptor tyrosine kinase EPHA4, with a Ki value of 0.65 μM. 123C4  Chemical Structure
  23. GC46474 18-Deoxyherboxidiene

    RQN-18690A

    A bacterial metabolite with antiangiogenic activity 18-Deoxyherboxidiene  Chemical Structure
  24. GC33087 2,4-Pyrimidinediamine with linker

    VEGFR-2-IN-5

    2,4-Pyrimidinediamine with linker is a VEGFR2 inhibitor extracted from patent WO2013055780A1, Page 69. 2,4-Pyrimidinediamine with linker  Chemical Structure
  25. GC33519 2,5-Dihydroxybenzoic acid

    Carboxyhydroquinone, 5-Hydroxysalicylic Acid, NSC 27224, NSC 49098, NSC 78825

    A benzoic acid with diverse biological activities 2,5-Dihydroxybenzoic acid  Chemical Structure
  26. GC10408 2-D08 Sumoylation inhibitor 2-D08  Chemical Structure
  27. GC33319 2-Keto Crizotinib (PF-06260182) 2-Keto Crizotinib (PF-06260182) (PF-06260182) is an active lactam metabolite of crizotinib. 2-Keto Crizotinib (PF-06260182)  Chemical Structure
  28. GC35095 2-Phospho-L-ascorbic acid trisodium salt 2-Phospho-L-ascorbic acid trisodium salt (2-Phospho-L-ascorbic acid trisodium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression. 2-Phospho-L-ascorbic acid trisodium salt  Chemical Structure
  29. GC39689 3-Hydroxy Midostaurin

    CGP52421

    3-Hydroxy Midostaurin (CGP 52421), a metabolite of PKC412, effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively. 3-Hydroxy Midostaurin is less selective but more cytotoxic than PKC412. 3-Hydroxy Midostaurin  Chemical Structure
  30. GC25017 4,4'-Bis(4-aminophenoxy)biphenyl 4,4'-Bis(4-aminophenoxy)biphenyl is a monomer for polyimide production. 4,4'-Bis(4-aminophenoxy)biphenyl  Chemical Structure
  31. GC46628 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline A building block and synthetic intermediate 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline  Chemical Structure
  32. GC12818 4-methyl Erlotinib EGFR inhibitor 4-methyl Erlotinib  Chemical Structure
  33. GC63805 4SC-203 4SC-203 is a potent multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively FLT3/STK1, FLT3 mutated forms, and VEGFRs. 4SC-203  Chemical Structure
  34. GC11205 5'-Fluoroindirubinoxime

    5’-FIO, 5′-Fluoroindirubinoxime

    FMS-like receptor tyrosine kinase-3 (FLT3) inhibitor 5'-Fluoroindirubinoxime  Chemical Structure
  35. GC68568 5α-Hydroxycostic acid

    5α-Hydroxycostic acid is a diterpenoid extracted from the herb Laggera alata. It inhibits angiogenesis and suppresses breast cancer cell migration by regulating the VEGF/VEGFR2 and Ang2/Tie2 pathways.

    5α-Hydroxycostic acid  Chemical Structure
  36. GC50157 6bK Insulin degrading enzyme (IDE) inhibitor 6bK  Chemical Structure
  37. GC16853 7,8-Dihydroxyflavone

    7,8-DHF

    Tyrosine kinase receptor B (TrkB) agonist 7,8-Dihydroxyflavone  Chemical Structure
  38. GC32992 7-Hydroxy-4-chromone (7-Hydroxychromone) 7-Hydroxychromone is a Src kinase inhibitor with an IC50 of <300 μM. 7-Hydroxy-4-chromone (7-Hydroxychromone)  Chemical Structure
  39. GC42616 7-oxo Staurosporine

    BMY 41950, RK-1409

    7-oxo Staurosporine is an antibiotic originally isolated from S.

    7-oxo Staurosporine  Chemical Structure
  40. GC48840 9-Methoxyellipticine

    Methoxy-9-ellipticine, NSC 69187

    An alkaloid with anticancer activity 9-Methoxyellipticine  Chemical Structure
  41. GC35209 A 419259

    RK-20449

    An inhibitor of Src family kinases A 419259  Chemical Structure
  42. GC17789 A 419259 trihydrochloride

    RK-20449

    LCK inhibitor, orally available A 419259 trihydrochloride  Chemical Structure
  43. GC35213 A-770041 A-770041 is a selective and orally active Src-family Lck inhibitor. A-770041  Chemical Structure
  44. GC35214 A-9758 A-9758 is a RORγ ligand and a potent, selective RORγt inverse agonist (IC50=5 nM), and exhibits robust potency against IL-17A release. A-9758  Chemical Structure
  45. GC10938 AAL-993

    VEGFR Tyrosine Kinase Inhibitor VI,ZK 260253

    VEGF receptors inhibitor AAL-993  Chemical Structure
  46. GC65894 ABN401 ABN401 is a highly potent and selective ATP-competitive c-MET inhibitor with an IC50 value of 10 nM. ABN401 has cytotoxic activity against MET-addicted cancer cells. ABN401 can inhibit c-MET phosphorylation in tumor tissues. ABN401 can be used for researching anticancer. ABN401  Chemical Structure
  47. GC13257 AC480 (BMS-599626)

    BMS-599626

    AC480 (BMS-599626) (AC480) is a selective and orally bioavailable HER1 and HER2 inhibitor, with IC50s of 20 and 30 nM, respectively. AC480 (BMS-599626) displays ~8-fold less potent to HER4 (IC50=190 nM), >100-fold to VEGFR2, c-Kit, Lck, MEK. AC480 (BMS-599626) inhibits tumor cell proliferation, and has potential to increase tumor response to radiotherapy. AC480 (BMS-599626)  Chemical Structure
  48. GC18167 AC710

    A potent and selective PDGFR family inhibitor

    AC710  Chemical Structure
  49. GC35225 AC710 Mesylate AC710 Mesylate is a potent PDGFR inhibitor with Kds of 0.6, 1.57, 1, 1.3, 1.0 nM for FLT3, CSF1R, KIT, PDGFRα and PDGFRβ, respectively. AC710 Mesylate  Chemical Structure
  50. GC68604 Acetyl Gastric Inhibitory Peptide (human) (TFA)

    Human N-acetyl GIP TFA

    Acetyl Gastric Inhibitory Peptide (human) TFA is a fatty acid derivative analog of glucose-dependent insulinotropic polypeptide, which has improved anti-hyperglycemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) TFA can be used for research on diabetes, insulin resistance, and obesity.

    Acetyl Gastric Inhibitory Peptide (human) (TFA)  Chemical Structure
  51. GC30242 Acrizanib

    LHA510

    Acrizanib (LHA510) is a VEGFR-2 inhibitor, with an IC50 of 17.4 nM for BaF3-VEGFR-2. Acrizanib  Chemical Structure
  52. GC15801 ACTB-1003

    ACTB-1003

    ACTB-1003 (ACTB-1003) is an oral kinase inhibitor with IC50s of 6, 2 and 4 nM for FGFR1, VEGFR2 and Tie-2. ACTB-1003  Chemical Structure
  53. GC68623 AD57

    AD57 is a type of orally active multi-kinase inhibitor that inhibits the activity of RET, BRAF, S6K and Src, but has significantly reduced activity against mTOR.

    AD57  Chemical Structure
  54. GC32797 AD80 AD80, a multikinase inhibitor, inhibits RET, RAF,SRCand S6K, with greatly reduced mTOR activity. AD80  Chemical Structure
  55. GC15579 Adaphostin

    NSC 680410

    P210bcr/abl tyrosine kinase inhibitor Adaphostin  Chemical Structure
  56. GC68626 Adhesamine

    Adhesamine is a dumbbell-shaped molecule that can activate the MAPK/FAK pathway. Adhesamine promotes adhesion and growth of mammalian cells. Adhesamine accelerates differentiation of primary cultured mouse hippocampal neurons and improves survival rate.

    Adhesamine  Chemical Structure
  57. GC11892 AEE788 (NVP-AEE788)

    NVP-AEE788

    AEE788 (NVP-AEE788) is an inhibitor of the EGFR and ErbB2 with IC50 values of 2 and 6 nM, respectively. AEE788 (NVP-AEE788)  Chemical Structure
  58. GC10707 Afatinib dimaleate

    Afatinib dimaleate, BIBW 2992, BIBW 2992MA2

    An inhibitor of EGFR and ErbB2 Afatinib dimaleate  Chemical Structure
  59. GC60567 Afatinib impurity 11 Afatinib impurity 11 is an impurity of Afatinib. Afatinib is an irreversible EGFR family inhibitor with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively. Afatinib impurity 11  Chemical Structure
  60. GC13296 Afatinib(BIBW2992) A selective dual inhibitor of EGFR/HER2 Afatinib(BIBW2992)  Chemical Structure
  61. GC46809 Afatinib-d6

    BIBW 2992 D6

    An internal standard for the quantification of afatinib Afatinib-d6  Chemical Structure
  62. GC68628 Aflibercept

    VEGF Trap; VEGF-TRAPR1R2; VEGF-trapR1

    Aflibercept is a high-affinity soluble decoy vascular endothelial growth factor (VEGF) receptor and a potent angiogenesis inhibitor that binds vascular endothelial growth factor and placental growth factor (PlGF) with extremely high affinity. Preclinical studies have shown that Aflibercept has potent antitumor and antiangiogenic activities against a variety of tumors, including melanoma and solid tumors. Aflibercept  Chemical Structure
  63. GC38645 AG 1295 AG 1295  Chemical Structure
  64. GC50013 AG 1478 hydrochloride Highly potent EGFR-kinase inhibitor AG 1478 hydrochloride  Chemical Structure
  65. GC17489 AG 494

    Tyrphostin AG-494

    Potent EGFR-kinase inhibitor AG 494  Chemical Structure
  66. GC11744 AG 555

    Tyrphostin AG-555, Tyrphostin B46

    Potent EGFR-kinase inhibitor AG 555  Chemical Structure
  67. GC12233 AG 556

    Tyrphostin 56, Tyrphostin AG-556

    AG 556 is a highly selective EGFR inhibitor and also blocks LPS-induced TNF-α production. AG 556  Chemical Structure
  68. GC13168 AG 825

    Tyrphostin AG825

    Selective ErbB2 inhibitor AG 825  Chemical Structure
  69. GC14494 AG 99

    Tyrphostin 46, Tyrphostin AG-99

    AG 99 ((E)-Tyrphostin 46) is a potent EGFR inhibitor. AG 99  Chemical Structure
  70. GC13697 AG-1024

    AGS 200, Tyrphostin AG1024

    Selective IGF-1R inhibitor AG-1024  Chemical Structure
  71. GC16235 AG-1295

    NSC 380341,Tyrphostin AG-1295

    potent and selective inhibitor of PDGF receptor kinase AG-1295  Chemical Structure
  72. GC35263 AG-13958 AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD). AG-13958  Chemical Structure
  73. GC17226 AG-1478

    Tyrphostin AG-1478; AG 1478; NSC 693255; AG1478

    EGFR inhibitor,potent and selective AG-1478  Chemical Structure
  74. GC12864 AG-1557

    Tyrphostin AG-1557

    inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase AG-1557  Chemical Structure
  75. GC17647 AG-18

    RG50810, RG50858, TX 825, Tyrphostin 23, Tyrphostin AG18

    AG-18 (Tyrphostin A23) is an EGFR inhibitor with an IC50 and Kiof 35 and 11 μM, respectively. AG-18  Chemical Structure
  76. GC14890 AG-183

    Tyrphostin 51

    AG-183 is the Z configuration of Lanoconazole A51. AG-183  Chemical Structure
  77. GC11024 AG-213

    Tyrphostin AG-213,Tyrphostin 47

    inhibitor of epidermal growth factor (EGF) receptor kinase AG-213  Chemical Structure
  78. GC11712 AG-370

    NSC 651712

    PDGFR inhibitor AG-370  Chemical Structure
  79. GC13854 AG-490 (Tyrphostin B42)

    Tyrphostin AG-490

    AG-490 (Tyrphostin B42) is EGFR inhibitor with IC50 of 0.1 µM, AG-490 also has an inhibitory effect on JAK2. AG-490 (Tyrphostin B42)  Chemical Structure
  80. GC11845 AG-82

    NSC 676484,RG-50875,Tyrphostin 25,Tyrphostin AG-82

    AG-82 (AG82) is a specific inhibitor of the EGFR tyrosine kinase. AG-82  Chemical Structure
  81. GC11737 AG957

    NSC 654705,Tyrphostin AG957

    a tyrphostin that targets transforming Bcr-Abl fusion proteins AG957  Chemical Structure
  82. GC31371 AGL-2263 An inhibitor of IGF-1R AGL-2263  Chemical Structure
  83. GC16228 AIM-100 An ACK1/TNK2 inhibitor AIM-100  Chemical Structure
  84. GC66451 AKN-028 acetate AKN-028 acetate, a novel tyrosine kinase (TK) inhibitor, is a potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC50 value of 6nM. AKN-028 acetate inhibits FLT3 autophosphorylation. AKN-028 acetate induces dose-dependent cytotoxic response (mean IC50=1μM). AKN-028 acetate induces apoptosisby activation of caspase 3. AKN-028 acetate can be used in research of acute myeloid leukemia (AML). AKN-028 acetate  Chemical Structure
  85. GC35280 Alectinib Hydrochloride Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration. Alectinib Hydrochloride  Chemical Structure
  86. GC35287 ALK inhibitor 1 ALK inhibitor 1 (compound 17) is a potent pyrimidin ALK inhibitor. ALK inhibitor 1 is a potent inhibitor of testis-specific serine/threonine kinase 2 (TSSK2; IC50=31 nM) and focal adhesion kinase (FAK; IC50=2 nM). ALK inhibitor 1  Chemical Structure
  87. GC17376 ALK inhibitor 2 An inhibitor of TSSK2 ALK inhibitor 2  Chemical Structure
  88. GC63387 ALK kinase inhibitor-1 ALK kinase inhibitor-1 is an anaplastic lymphoma kinase (ALK) inhibitor extracted from patent US20130261106A1 compound I-202. ALK kinase inhibitor-1  Chemical Structure
  89. GC35289 ALK-IN-5 ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK), with an IC50 of 2.9 nM. ALK-IN-5  Chemical Structure
  90. GC35290 ALK-IN-6 ALK-IN-6 (compound 11) is an orally bioavailable inhibitor of anaplastic lymphoma kinase (ALK), with IC50 values of 71 nM, 18.72 nM and 36.81 nM for ALK wild, ALK F1196M and ALK F1174L, respectively. ALK-IN-6  Chemical Structure
  91. GC64398 Almonertinib mesylate

    HS-10296 mesylate

    Almonertinib (HS-10296) mesylate is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib mesylate shows great inhibitory activity against T790M, T790M/L858R and T790M/Del19 (IC50: 0.37, 0.29 and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). Almonertinib mesylate is used for the research of the non-small cell lung cancer. Almonertinib mesylate  Chemical Structure
  92. GC32127 Alofanib (RPT835)

    RPT835

    Alofanib (RPT835) (RPT835) is a potent and selective allosteric inhibitor of fibroblast growth factor receptor 2 (FGFR2). Alofanib (RPT835)  Chemical Structure
  93. GC16604 Altiratinib

    DCC-2701

    c-MET/TIE-2/VEGFR inhibitor Altiratinib  Chemical Structure
  94. GC11134 ALW-II-41-27

    Eph receptor tyrosine kinase inhibitor;

    ALW-II-41-27 is an Eph family tyrosine kinase inhibitor with an IC50 of 11 nM to inhibit Eph2. ALW-II-41-27  Chemical Structure
  95. GC68647 ALW-II-49-7

    ALW-II-49-7 is a selective inhibitor of EphB2 with an intracellular EC50 of 40 nM.

    ALW-II-49-7  Chemical Structure
  96. GC15655 AMG 337 MET inhibitor AMG 337  Chemical Structure
  97. GC14974 AMG 925 FLT3/CDK4 inhibitor,potent and selective AMG 925  Chemical Structure
  98. GC35315 AMG 925 HCl AMG 925 HCl is a potent, selective, and orally available FLT3/CDK4 dual inhibitor with IC50s of 2±1 nM and 3±1 nM, respectively. AMG 925 HCl  Chemical Structure
  99. GC12600 AMG-208 C-Met inhibitor,potent and highly selective AMG-208  Chemical Structure
  100. GC11481 AMG-458

    AMG 458; AMG458

    Potent c-Met inhibitor AMG-458  Chemical Structure
  101. GC17669 AMG-47A destabilizer of the KRAS oncoprotein AMG-47A  Chemical Structure

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