GLPBio

BPN-01

Catalog No.: GC92024Purity:>90.00%
BPN-01 is a fluorescent probe for cancer cells.

Products are for research use only. Not for human use. We do not sell to patients.


BPN-01
1 mgIn Stock
$91.00
1
5 mgIn Stock
$386.00
1
10 mgIn Stock
$683.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

BPN-01 is a fluorescent probe for cancer cells.1 BPN-01 displays an emission maximum of 500 nm upon excitation at 475 nm. It selectively accumulates in DU145 prostate cancer and B16/F10 murine melanoma cells over C2C12 mouse skeletal muscle myoblasts. In vivo, BPN-01 selectively accumulates in tumor tissue over the kidney and liver in an RM-1 prostate cancer mouse xenograft model.

References:
[1]. Wongso, H., Goenawan, H., Lesmana, R., et al.Synthesis and biological evaluation of new fluorescent probe BPN-01: A model molecule for fluorescence image-guided surgeryJ. Fluoresc.33(5)1827-1839(2023).

Product Documents

Purity:>90.00%Appearance:A solid

Chemical Properties

Chemical Name
6-methoxy-N-(4-(((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)methyl)phenyl)benzo[d]thiazole-2-carboxamide
SMILES
COC1=CC=C2C(SC(C(NC3=CC=C(CNC4=CC=C([N+]([O-])=O)C5=NON=C45)C=C3)=O)=N2)=C1
Molecular Formula
C22H16N6O5S
Molecular Weight
476.5
Solubility
Acetonitrile: Slightly soluble: 0.1-1 mg/ml
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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