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Home >> Signaling Pathways >> Cancer Biology

Cancer Biology

Products for  Cancer Biology

  1. Cat.No. Product Name Information
  2. GC40702 α-D-Galactopyranosylphenyl isothiocyanate

    α-D-Galactopyranosylphenyl isothiocyanate is a chemically activated form of galactose that has been used to prepare various neoglycoproteins, which consist of a glycosylated serum albumin substituted with either fluorescein or methotrexate.

     α-D-Galactopyranosylphenyl isothiocyanate Chemical Structure
  3. GC45207 α-hydroxy Farnesyl Phosphonic Acid α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase). α-hydroxy Farnesyl Phosphonic Acid Chemical Structure
  4. GC41499 α-Phellandrene α-Phellandrene is a cyclic monoterpene that has been found in various plants, including Cannabis, and has diverse biological activities. α-Phellandrene Chemical Structure
  5. GC49467 β-Aescin A triterpenoid saponin with diverse biological activities β-Aescin Chemical Structure
  6. GC40789 β-Cembrenediol β-Cembrenediol (β-CBT) is a natural product from tobacco plants that is found in cigarette smoke condensate. β-Cembrenediol Chemical Structure
  7. GC45604 β-Rubromycin   β-Rubromycin Chemical Structure
  8. GC41109 δ12-Prostaglandin J2 δ12-PGJ2 is a decomposition product of PGD2 in aqueous media in the presence of albumin. δ12-Prostaglandin J2 Chemical Structure
  9. GC41669 (±)-Enterolactone

    Diets high in fiber contain plant lignan species that may be directly responsible for some observed health benefits of these diets.

     (±)-Enterolactone Chemical Structure
  10. GC41671 (±)-Equol 4'-sulfate (sodium salt)

    (±)-Equol 4'-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol.

     (±)-Equol 4'-sulfate (sodium salt) Chemical Structure
  11. GC46000 (•)-Drimenol (•)-Drimenol Chemical Structure
  12. GC45250 (-)-L-threo-PDMP (hydrochloride) (-)-L-threo-PDMP is an enhancer of ganglioside biosynthesis. (-)-L-threo-PDMP (hydrochloride) Chemical Structure
  13. GC45251 (-)-Neplanocin A S-Adenosylhomocysteine (SAH) hydrolase catalyzes the reversible hydrolysis of SAH to adenosine and homocysteine. (-)-Neplanocin A Chemical Structure
  14. GC45253 (-)-Viriditoxin (-)-Viriditoxin is a mycotoxin originally isolated from A. (-)-Viriditoxin Chemical Structure
  15. GC46038 (5E)-7-Oxozeaenol (5E)-7-Oxozeaenol Chemical Structure
  16. GC41702 (E)-5-(2-Bromovinyl)uracil (E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of the antiviral agents sorivudine and (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) that may be regenerated to BVDU in vivo. (E)-5-(2-Bromovinyl)uracil Chemical Structure
  17. GC41620 (R)-(-)-Mellein (R)-(-)-Mellein is a dihydroisocoumarin compound produced by A. (R)-(-)-Mellein Chemical Structure
  18. GC41741 (S)-α-Methylbenzyl Ricinoleamide (S)-α-Methylbenzyl ricinoleamide is a fatty acid amide derived from ricinoleic acid and methyl benzylamine. (S)-α-Methylbenzyl Ricinoleamide Chemical Structure
  19. GC18787 (±)-Dunnione (±)-Dunnione is a naturally occurring naphthoquinone with diverse biological activities. (±)-Dunnione Chemical Structure
  20. GC46039 1,2,3,4-Tetrahydrostaurosporine 1,2,3,4-Tetrahydrostaurosporine Chemical Structure
  21. GA20357 1,2-Dimyristoyl-rac-glycerol 1,2-Dimyristoyl-rac-glycerol Chemical Structure
  22. GC41823 1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt)

    1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) is a biotinylated phospholipid.

     1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt) Chemical Structure
  23. GC41986 1-Arachidonoyl Lysophosphatidic Acid (ammonium salt)

    1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position.

     1-Arachidonoyl Lysophosphatidic Acid (ammonium salt) Chemical Structure
  24. GC42001 1-Myristoyl-2-hydroxy-sn-glycero-3-PE 1-Myristoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring lysophospholipid. 1-Myristoyl-2-hydroxy-sn-glycero-3-PE Chemical Structure
  25. GC18651 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE

    1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid.

     1-Palmitoyl-2-hydroxy-sn-glycero-3-PE Chemical Structure
  26. GC41331 1-Stearoyl-2-hydroxy-sn-glycero-3-PC 1-Stearoyl-2-hydroxy-sn-glycero-3-PC is a saturated 18:0 lysophosphatidylcholine found in plasma and oxidized LDL that is thought to play a role in inflammatory diseases and atherosclerosis. 1-Stearoyl-2-hydroxy-sn-glycero-3-PC Chemical Structure
  27. GC40176 1-Stearoyl-rac-glycerol 1-Stearoyl-rac-glycerol is a monoacylglycerol that contains stearic acid at the sn-1 position. 1-Stearoyl-rac-glycerol Chemical Structure
  28. GC18637 11β-Prostaglandin F2α

    11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo.

     11β-Prostaglandin F2α Chemical Structure
  29. GC41950 16α-hydroxy Estrone The naturally-occurring estrogens are estrone, estradiol, and estriol. 16α-hydroxy Estrone Chemical Structure
  30. GC41942 16,16-dimethyl Prostaglandin A2 16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life. 16,16-dimethyl Prostaglandin A2 Chemical Structure
  31. GC41300 17β-hydroxy Exemestane 17β-hydroxy Exemestane is the primary active metabolite of exemestane. 17β-hydroxy Exemestane Chemical Structure
  32. GC45307 17(R)-Resolvin D3   17(R)-Resolvin D3 Chemical Structure
  33. GC40947 2,3-Dimethoxy-5-methyl-p-benzoquinone 2,3-Dimethoxy-5-methyl-p-benzoquinone, also known as coenzyme Q0, is a key intermediate in the synthesis of coenzyme Q, coenzyme Q10, other ubiquinones, and vitamin E. 2,3-Dimethoxy-5-methyl-p-benzoquinone Chemical Structure
  34. GC52029 2-Aminoflubendazole A metabolite of flubendazole 2-Aminoflubendazole Chemical Structure
  35. GC42170 2-hydroxy Stearic Acid 2-hydroxy Stearic acid is a naturally occurring hydroxylated fatty acid that has been found in humans and U. 2-hydroxy Stearic Acid Chemical Structure
  36. GC40944 2-hydroxy-6-Methylbenzoic Acid 2-hydroxy-6-Methylbenzoic acid is a constituent of G. 2-hydroxy-6-Methylbenzoic Acid Chemical Structure
  37. GC13460 2-Hydroxyestradiol

    anti-cancer agent acting as an angiogenesis inhibitor via the HIF-1a pathway

     2-Hydroxyestradiol Chemical Structure
  38. GC42203 3,4',5-Trismethoxybenzophenone Resveratrol is a potent phenolic antioxidant found in natural sources that has antiproliferative activity. 3,4',5-Trismethoxybenzophenone Chemical Structure
  39. GC42260 3-Deazauridine

    3-Deazauridine is a nucleoside analog.

     3-Deazauridine Chemical Structure
  40. GC45337 3-Hydroxyterphenyllin   3-Hydroxyterphenyllin Chemical Structure
  41. GC40045 4-(Dimethylamino)-1-methylpyridinium (iodide) 4-(Dimethylamino)-1-methylpyridinium is a monoquaternary pyridinium salt with anticholinesterase and antiproliferative activities. 4-(Dimethylamino)-1-methylpyridinium (iodide) Chemical Structure
  42. GC42411 4-hydroxy Nonenal Alkyne 4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid. 4-hydroxy Nonenal Alkyne Chemical Structure
  43. GC41530 4-oxo Docosahexaenoic Acid 4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity. 4-oxo Docosahexaenoic Acid Chemical Structure
  44. GC40053 5α,6α-epoxy Cholestanol An oxysterol and a metabolite of cholesterol produced by oxidation 5α,6α-epoxy Cholestanol Chemical Structure
  45. GC18826 5'-chloro-5'-Deoxyadenosine (hydrate) 5'-chloro-5'-Deoxyadenosine (hydrate) is a nucleoside analog used as a substrate in polyketide biosynthesis. 5'-chloro-5'-Deoxyadenosine (hydrate) Chemical Structure
  46. GC42503 5'-deoxy-5-Fluorocytidine 5'-deoxy-5-Fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine. 5'-deoxy-5-Fluorocytidine Chemical Structure
  47. GC49499 5(Z)-Dodecenoic Acid A medium-chain unsaturated fatty acid 5(Z)-Dodecenoic Acid Chemical Structure
  48. GC18542 5,6-dihydro-5-Fluorouracil

    5,6-dihydro-5-Fluorouracil (5-FUH2) is formed by the hydrogenation of 5-fluorouracil via the enzyme dihydropyrimidine dehydrogenase (DPD).

     5,6-dihydro-5-Fluorouracil Chemical Structure
  49. GC40527 5-(Hydroxymethyl)-2'-deoxyuridine 5-(Hydroxymethyl)-2'-deoxyuridine is a nucleoside analog with anticancer and antiviral activities. 5-(Hydroxymethyl)-2'-deoxyuridine Chemical Structure
  50. GC46033 5-Heneicosylresorcinol 5-Heneicosylresorcinol Chemical Structure
  51. GC52172 5-hydroxy Indole-3-acetic Acid-d6 5-hydroxy Indole-3-acetic Acid-d6 Chemical Structure
  52. GC64610 5-O-Caffeoylshikimic acid 5-O-Caffeoylshikimic acid Chemical Structure
  53. GC41310 5-Octyl-α-ketoglutarate In addition to its role in the Krebs cycle, α-ketoglutarate (2-oxoglutarate) has roles as a substrate or modulator of enzymes. 5-Octyl-α-ketoglutarate Chemical Structure
  54. GC49629 6β-hydroxy Prednisolone A metabolite of prednisolone 6β-hydroxy Prednisolone Chemical Structure
  55. GC49551 6-Chloropurine Riboside A nucleoside precursor 6-Chloropurine Riboside Chemical Structure
  56. GC42608 7-hydroxy Methotrexate (sodium salt)

    7-hydroxy Methotrexate (7-hydroxy MTX) is a phase I metabolite of MTX, which is converted by hepatic aldehyde oxidases.

     7-hydroxy Methotrexate (sodium salt) Chemical Structure
  57. GC49561 7-Methylguanosine-d3 An internal standard for the quantification of 7-methylguanosine 7-Methylguanosine-d3 Chemical Structure
  58. GC52142 80-O16B 80-O16B Chemical Structure
  59. GC41642 9(E),11(E),13(E)-Octadecatrienoic Acid 9(E),11(E),13(E)-Octadecatrienoic acid (β-ESA) is a conjugated polyunsaturated fatty acid that is found in plant seed oils and in mixtures of conjugated linolenic acids synthesized by the alkaline isomerization of linolenic acid. 9(E),11(E),13(E)-Octadecatrienoic Acid Chemical Structure
  60. GC42644 9-Deazaguanine 9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM). 9-Deazaguanine Chemical Structure
  61. GC42645 9-Ethylguanine 9-Ethylguanine is a model nucleobase that is used to study DNA interactions with organometallic complexes, especially those designed to target tumors. 9-Ethylguanine Chemical Structure
  62. GP10113 Adrenomedullin (1-12), human Vasodilator Adrenomedullin (1-12), human Chemical Structure
  63. GP10109 Adrenorphin

    Endogenous μ/κ opioid agonist,potent and selective

     Adrenorphin Chemical Structure
  64. GC11189 AI-10-49 Inhibitor of CBFβ –SMMHC and RUNX1 interaction AI-10-49 Chemical Structure
  65. GC18482 all-trans-5,6-epoxy Retinoic Acid all-trans-5,6-epoxy Retinoic acid (5,6-epoxy RA) is an agonist of all isoforms of the retinoic acid receptor (RAR; EC50s = 77, 35, and 4 nM for RARα, RARβ, and RARγ, respectively). all-trans-5,6-epoxy Retinoic Acid Chemical Structure
  66. GP10057 Amyloid β-Peptide (10-20) (human)

    Initiates neurodegeneration in Alzheimer disease

     Amyloid β-Peptide (10-20) (human) Chemical Structure
  67. GC40674 APHA Compound 8 APHA Compound 8 Chemical Structure
  68. GC42854 ARN14988 ARN14988 is a potent inhibitor of acid ceramidase (IC50 = 12.8 nM for the human enzyme). ARN14988 Chemical Structure
  69. GC46089 Asperfuran Asperfuran Chemical Structure
  70. GC42861 Aspochalasin M Aspochalasin M is a fungal metabolite originally isolated from S. Aspochalasin M Chemical Structure
  71. GC46090 Aspulvinone O Aspulvinone O Chemical Structure
  72. GC46091 Aszonapyrone A Aszonapyrone A Chemical Structure
  73. GC42870 Atrazine Mercapturate Atrazine mercapturate is a major, glutathione-derived metabolite of atrazine, an herbicide that is effective in controlling a broad range of weeds. Atrazine Mercapturate Chemical Structure
  74. GC45938 Bacopaside X Bacopaside X Chemical Structure
  75. GC50603 BAY 293 Negative Control Negative control for BAY 293 BAY 293 Negative Control Chemical Structure
  76. GC41532 Benzisoxazole Hsp90 Inhibitor Heat shock protein 90 (Hsp90) is a molecular chaperone that modulates intracellular signaling and protein folding, trafficking, and turnover. Benzisoxazole Hsp90 Inhibitor Chemical Structure
  77. GC42925 Berteroin Berteroin is a sulforaphane analog found in cruciferous vegetables including Chinese cabbage, rucola salad leaves, and mustard oil. Berteroin Chemical Structure
  78. GC42941 Bis(methylthio)gliotoxin Bis(methylthio)gliotoxin is a fungal metabolite originally isolated from G. Bis(methylthio)gliotoxin Chemical Structure
  79. GC49654 BMS 270394 A RARγ agonist BMS 270394 Chemical Structure
  80. GA21046 Boc-Leu-Leu-OH Boc-Leu-Leu-OH Chemical Structure
  81. GC42967 Boromycin Boromycin is a boron-containing macrolide antibiotic that has been found in Streptomyces. Boromycin Chemical Structure
  82. GC10612 BQU57 Derivative of RBC8 BQU57 Chemical Structure
  83. GC46106 Butyrolactone V Butyrolactone V Chemical Structure
  84. GC43007 C12 Galactosylceramide (d18:1/12:0) C12 Galactosylceramide is a bioactive sphingolipid. C12 Galactosylceramide (d18:1/12:0) Chemical Structure
  85. GC43032 C16 Globotriaosylceramide (d18:1/16:0) C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide. C16 Globotriaosylceramide (d18:1/16:0) Chemical Structure
  86. GC43035 C16 Sphingomyelin (d18:1/16:0) Sphingomyelins are complex membrane lipids composed of phosphorylcholine, sphingosine, and an acylated group, such as a fatty acid. C16 Sphingomyelin (d18:1/16:0) Chemical Structure
  87. GC43047 C18 Ceramide (d18:1/18:0)

    C18 Ceramide is an endogenous bioactive sphingolipid.

     C18 Ceramide (d18:1/18:0) Chemical Structure
  88. GC43055 C18:1 Ceramide (d18:1/18:1(9Z))

    C18:1 Ceramide is a naturally occurring ceramide.

     C18:1 Ceramide (d18:1/18:1(9Z)) Chemical Structure
  89. GC43068 C20 Sphingomyelin (d18:1/20:0) C20 Sphingomyelin is a naturally occurring sphingolipid. C20 Sphingomyelin (d18:1/20:0) Chemical Structure
  90. GC43071 C22 Sphingomyelin (d18:1/22:0) C22 Sphingomyelin is a naturally occurring form of sphingomyelin. C22 Sphingomyelin (d18:1/22:0) Chemical Structure
  91. GC43110 C8 Galactosylceramide (d18:1/8:0) C8 Galactosylceramide is a synthetic C8 short-chain derivative of known membrane microdomain-forming sphingolipids. C8 Galactosylceramide (d18:1/8:0) Chemical Structure
  92. GP10127 Cadherin Peptide, avian

    Role in cell adhesion

     Cadherin Peptide, avian Chemical Structure
  93. GC43135 Cambendazol Cambendazol is an antihelmintic that, at a dose of 50 mg/kg/day in mice, eradicates S. Cambendazol Chemical Structure
  94. GC43139 Capsanthin Capsanthin is a carotenoid that has been found in red paprika and has diverse biological activities. Capsanthin Chemical Structure
  95. GC18449 Cardanol monoene Cardanol monoene is a phenol found in cashew nut shell liquid that reversibly inhibits tyrosinase with an IC50 value of 56 uM in vitro. Cardanol monoene Chemical Structure
  96. GC43153 CAY10416 Dual cyclooxygenase-2 (COX-2)/5-lipoxygenase (5-LO) inhibitors are potential therapeutic agents for inflammatory diseases and for prostate cancer. CAY10416 Chemical Structure
  97. GC18949 CAY10677 Post-translational protein prenylation is a 3-step process that occurs at the C-terminus of a number of proteins involved in cell growth control and oncogenesis. CAY10677 Chemical Structure
  98. GC40890 CAY10701 CAY10701 is a 7-deazahypoxanthine analog that prevents microtubule formation, blocking the proliferation of HeLa and MCF-7 cells (GI50s = 22 and 38 nM, respectively). CAY10701 Chemical Structure
  99. GC43204 CAY10730 CAY10730 is a turn-on fluorescent probe for the detection of nitroreductase activity, a marker of hypoxia. CAY10730 Chemical Structure
  100. GC45404 CAY10736   CAY10736 Chemical Structure
  101. GC43207 Caylin-1 Nutlin-3 is an activator of p53 that functions by inhibiting the interaction of p53 with MDM2, a negative regulator of p53 activity. Caylin-1 Chemical Structure

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