C3 |
Catalog No.GC49573 |
An inhibitor of MAO-B
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2286257-25-6
Sample solution is provided at 25 µL, 10mM.
C3 is an inhibitor of monoamine oxidase B (MAO-B; IC50 = 0.021 µM).1 It is selective for MAO-B over MAO-A (IC50 = 26.8 µM). C3 (0.1, 1, and 3 mg/kg) prevents MPTP-induced decreases in brain dopamine levels in mice.
1.Jin, C.-F., Wang, Z.-Z., Chen, K.-Z., et al.Computational fragment-based design facilitates discovery of potent and selective monoamine oxidase-B (MAO-B) inhibitorJ. Med. Chem.63(23)15021-15036(2020)
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