Neuroscience

Neuroscience
Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides).
Products for Neuroscience
- 5-HT Receptor(460)
- AChR(50)
- AChE(91)
- Alzheimer(65)
- Amyloid β(95)
- BACE(5)
- CGRP (22)
- COX(258)
- DAPK(4)
- Dopamine Receptor(256)
- GABA Receptor(198)
- Gap Junction(10)
- GluR(118)
- Histamine(1)
- Histamine Receptor(214)
- mPEGS-1(3)
- Muscarinic Receptor(38)
- Neuroscience Peptides(1)
- Nicotinic Receptor(59)
- P2 Receptor(2)
- P2X7 receptor(2)
- SSRIs(5)
- Substance P/NK1 Receptor(20)
- NMDA(2)
- Cholecystokinin Receptor(22)
- GPR139(2)
- mAChR(128)
- MCHR1 (GPR24)(15)
- Neurokinin Receptor(55)
- iGluR(119)
- nAChR(54)
- Beta-secretase(22)
- CaMK(23)
- Dopamine Transporter(17)
- Monoamine Oxidase(67)
- Serotonin Transporter(49)
- Behavioral Neuroscience(257)
- Huntington(9)
- Neuroendocrinology(39)
- Neuroprotection(76)
- Ophthalmology(112)
- Pain Research(154)
- Parkinson(45)
- Seizure Disorders(66)
- Prion(6)
- Cholinesterases(9)
- Cat.No. Product Name Information
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GC20172
N-Isopropylphthalimide
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GC26093
α-Conotoxin GI
α-Conotoxin GI, a 13-residue peptide originally isolated from the venom of the fish-hunting cone snail Conus geographus, acts as a competitive antagonist for the muscle-type nicotinic acetylcholine receptor (nAChR) with excellent selectivity for α/δ receptor subunit binding over α/γ.
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GC26056
WAY-303290
WAY-303290 (GluR6 antagonist-1) is a benzothiophene derivative acting as an ionotropic glutamate receptor 6 (GluR6) antagonist, which can be used for researching acute and chronic neurological disorders.
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GC26035
Verubecestat (MK-8931) Trifluoroacetate
Verubecestat (MK-8931) Trifluoroacetate is a potent and selective beta-secretase inhibitor and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor.
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GC26032
Varenicline (CP 526555) dihydrochloride
Varenicline (CP 526555, Chantix, Champix,CP 526555 dihydrochloride) dihydrochloride is a potent, partial agonist of α4β2 nicotinic acetylcholine receptor (nAChR) and α3β4 nAChR with EC50 of 2.3 μM and 55 μM, respectively. Varenicline dihydrochloride is a potent, full agonist of α7 nAChRs with EC50 of 18 μM. Varenicline is a prescription medication used for smoking cessation.
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GC26002
Trazodone
Trazodone (AF-1161) is a 5-HT 2A/2C receptor antagonist that is used as an antidepressant for treating major depressive disorder and anxiety disorders.
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GC25994
Thonzylamine
Thonzylamine (Neohetramine) is an antihistamine and anticholinergic drug.
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GC25898
SB 200646
SB 200646 (SB 200646A) is a potent, selective and oral-active antagonist of 5-HT2B/2C over 5-HT2A receptor with 50 fold selectivity. The pKi for rat 5-HT2C receptor, rat 5-HT2B receptor and rat 5-HT2A receptor are 6.9, 7.5 and 5.2, respectively. SB 200646 has electrophysiological and anxiolytic properties in vivo.
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GC25785
Promethazine
Promethazine is a potent histamine H1 receptor antagonist. Promethazine is a medication used in the management and treatment of allergic conditions, nausea and vomiting, motion sickness, and sedation. Promethazine exhibits antiparasitic properties.
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GC25756
Pirenperone
Pirenperone (R-47456, R-50656), a quinazoline derivative, is a selective antagonist of SR-2A (5-HT2 serotonin receptor) when employed in low doses. Pirenperone behaves like a typical neuroleptic when used in higher doses (greater than 0.1 mg/kg).
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GC25708
Paroxetine mesylate
Paroxetine Mesylate(BRL-29060A mesylate,FG-7051 mesylate) is the mesylate salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties.
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GC25618
Maropitant citrate
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GC25583
Lobelin sulphate
Lobelin sulphate (Lobeline sulfate, Bantron) is an alkaloid that has actions similar to nicotine on nicotinic cholinergic receptors but is less potent. It has a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation.
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GC25571
Levocetirizine
Levocetirizine (LCZ, (R)-Cetirizine), the R-enantiomer of cetirizine, is an antagonist of histamine H(1) receptor.
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GC25569
Lerisetron
Lerisetron (F 0930, F 0930RS) is a 5-HT3 receptor antagonist with IC50 of 0.81μM.
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GC25566
L-DAB HBR
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GC25563
Lasmiditan succinate
Lasmiditan succinate (COL-144, LY573144) is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (Ki=2.21 nM) without vasoconstrictor activity.
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GC25531
Isonipecotic acid
Isonipecotic acid (4-Piperidinecarboxylic acid, 4-Carboxypiperidine, Hexahydroisonicotinic acid) is a heterocyclic compound that mainly acts as a GABAA receptor partial agonist.
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GC25434
Frovatriptan Succinate
Frovatriptan Succinate(SB 209509 Succinate,VML 251 Succinate) is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors.
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GC25387
Ethyl (triphenylphosphoranylidene) acetate
Ethyl (triphenylphosphoranylidene) acetate (Triphenylcarbethoxymethylenephosphorane, (Carbethoxymethylene)triphenylphosphorane) may act as an inhibitor of cholinesterase that inhibits AChE and BChE.
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GC25259
Cisapride hydrate
Cisapride (Propulsid, Alimix, Propulsin, Enteropride, Kinestase) acts directly as a selective serotonin 5-HT4 receptor agonist with IC50 of 0.483 μM. And It also acts indirectly as a parasympathomimetic.
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GC25253
Cinitapride Hydrogen Tartrate
Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors
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GC25136
Betazole Dihydrochloride
Betazole Dihydrochloride (Ametazole, 2-(3-Pyrazolyl)ethanamine) is a histamine H2 agonist used clinically to test gastric secretory function.
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GC25060
Amitriptyline
Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. Amitriptyline is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. This product is a waxy solid.
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GC68438
AMPA receptor modulator-3
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GC68423
Indomethacin-d4 Methyl Ester
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GC68422
Choline-d4 chloride
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GC68420
Propionylpromazine-d6 hydrochloride
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GC68410
(S)-Mirtazapine-d3
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GC68409
Cetirizine D8
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GC68383
(R)-Preclamol
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GC68377
OAB-14
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GC68364
Flibanserin-d4-1
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GC68363
SEN177
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GC68335
N-Demethyl MK-6884
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GC68330
Histamine-α,α,β,β-d4 dihydrochloride
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GC68328
3-Hydroxy agomelatine-d3
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GC68326
Ipratropium-d3 bromide
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GC68323
Flurbiprofen-d5
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GC68307
Fluphenazine-d8 dihydrochloride
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GC68299
Simtuzumab
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GC68210
(+)-Norfenfluramine
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GC68206
Propionylpromazine
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GC68016
COX-2-IN-6
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GC68014
Seliforant
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GC67996
TPA-023B
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GC67995
Ketotifen-d3 fumarate
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GC67989
(S)-Mirtazapine
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GC67979
MK-6884
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GC67944
Cetirizine D4
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GC67937
(R)-Mirtazapine
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GC67923
Renzapride
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GC67922
Zelquistinel
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GC67882
VU6028418
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GC67752
Pimozide-d4-1
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GC67705
Naxagolide
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GC52514
Arachidonic Acid-d11 ethyl ester
An internal standard for the quantification of arachidonic acid ethyl ester
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GC52507
Orexin A amide (bovine, human, mouse, rat) (trifluoroacetate salt)
A hypothalamic neuropeptide
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GC52505
Ganglioside GT1b (bovine) (sodium salt)
A sphingolipid
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GC52502
Peptide YY (3-36) (trifluoroacetate salt)
A satiety hormone
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GC52500
Dynorphin A (trifluoroacetate salt)
An endogenous opioid receptor agonist
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GC52498
NGB 2904 (hydrochloride)
A selective D3 antagonist
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GC52497
Lactosylceramide (porcine RBC)
A sphingolipid
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GC52496
Sulfatide (bovine) (sodium salt)
A mixture of isolated bovine sulfatides
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GC52495
AF-353 (hydrochloride)
A dual P2X3 and P2X2/3 receptor antagonist
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GC52494
β-Endorphin (rat) (trifluoroacetate salt)
An opioid neuropeptide
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GC52493
Glucosylceramide (bovine buttermilk)
A sphingolipid
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GC52492
Globotriaosylceramide (hydroxy) (porcine RBC)
A sphingolipid
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GC52491
Globotriaosylceramide (non-hydroxy) (porcine RBC)
A sphingolipid
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GC52487
Ganglioside GM4 (chicken egg) (ammonium salt)
A sphingolipid
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GC52486
Ceramide Phosphoethanolamine (bovine)
A sphingolipid
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GC52484
Purified Ganglioside Mixture (bovine) (ammonium salt)
A mixture of purified bovine gangliosides
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GC52483
Fucosylated Ganglioside GM1 (porcine) (ammonium salt)
A sphingolipid
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GC52477
Corynoxine (hydrochloride)
An indole alkaloid
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GC52476
Bax Inhibitor Peptide V5 (trifluoroacetate salt)
A Bax inhibitor
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GC52473
NVP-AAM077
An NMDA receptor antagonist
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GC52453
Orexin A (17-33) (human, mouse, rat, bovine) (trifluoroacetate salt)
A peptide orexin receptor 1 agonist
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GC52449
Spadin (trifluoroacetate salt)
An inhibitor of K2P2.1/TREK1
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GC52438
CGRP (8-37) (mouse, rat) (trifluoroacetate salt)
A CGRP receptor antagonist
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GC52424
Bradykinin Fragment (1-5) (trifluoroacetate salt)
A metabolite of bradykinin
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GC52421
(±)-10-hydroxy-12(Z)-Octadecenoic Acid-d5
An internal standard for the quantification of (±)-10-hydroxy-12(Z)-octadecenoic acid
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GC52419
MOG (35-55) (mouse, rat) (trifluoroacetate salt)
An MOG antigen peptide
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GC52414
[Ala17]-MCH (trifluoroacetate salt)
An MCH-derived peptide and MCH receptor agonist
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GC52412
TT-232 (trifluoroacetate salt)
A synthetic peptide derivative of somatostatin
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GC52411
Exendin-4 (5-39) amide (trifluoroacetate salt)
An antagonist of the GLP-1 receptor
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GC52409
BAM-22P (8-22) (human, mouse, rat, bovine) (trifluoroacetate salt)
A neuropeptide and MRGPRX1 agonist
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GC52407
BAM-22P (human, mouse, rat, bovine) (trifluoroacetate salt)
A neuropeptide
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GC52403
Ivermectin-d2
An internal standard for the quantification of ivermectin
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GC52399
Norephedrine-d5 (hydrochloride)
An internal standard for the quantification of norephedrine
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GC52391
306-O12B-3
An ionizable cationic lipidoid
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GC52390
Spexin 1 (human, mouse, rat, bovine) (acetate)
An endogenous peptide and agonist of GAL2 and GAL3
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GC52389
Caveolin-1 (82-101) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
A synthetic peptide fragment of caveolin-1
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GC52388
[D-Lys3]-GHRP-6 (trifluoroacetate salt)
An antagonist of GHS-R1a
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GC52385
Myelin Basic Protein (85-99) Peptide Antagonist (trifluoroacetate salt)
An MBP (85-99) antagonist
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GC52382
Nogo-66 (1-40) (human, mouse, rat) (trifluoroacetate salt)
A peptide fragment of Nogo-A
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GC52354
Tertiapin Q (trifluoroacetate salt)
A peptide derivative of tertiapin
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GC52342
P4pal10 (trifluoroacetate salt)
A PAR4 and FPR2 antagonist and an FFAR2 agonist
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GC52332
Arimoclomol
A co-inducer of heat shock proteins
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GC52331
Lactoyl Phenylalanine
A secondary metabolite
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GC52329
Betamethasone-d5
An internal standard for the quantification of betamethasone