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Home >> Signaling Pathways >> Neuroscience

Neuroscience

Neuroscience

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides).

Products for  Neuroscience

  1. Cat.No. Product Name Information
  2. GC20172 N-Isopropylphthalimide N-Isopropylphthalimide Chemical Structure
  3. GC26093 α-Conotoxin GI α-Conotoxin GI, a 13-residue peptide originally isolated from the venom of the fish-hunting cone snail Conus geographus, acts as a competitive antagonist for the muscle-type nicotinic acetylcholine receptor (nAChR) with excellent selectivity for α/δ receptor subunit binding over α/γ. α-Conotoxin GI Chemical Structure
  4. GC26056 WAY-303290 WAY-303290 (GluR6 antagonist-1) is a benzothiophene derivative acting as an ionotropic glutamate receptor 6 (GluR6) antagonist, which can be used for researching acute and chronic neurological disorders. WAY-303290 Chemical Structure
  5. GC26035 Verubecestat (MK-8931) Trifluoroacetate Verubecestat (MK-8931) Trifluoroacetate is a potent and selective beta-secretase inhibitor and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat (MK-8931) Trifluoroacetate Chemical Structure
  6. GC26032 Varenicline (CP 526555) dihydrochloride Varenicline (CP 526555, Chantix, Champix,CP 526555 dihydrochloride) dihydrochloride is a potent, partial agonist of α4β2 nicotinic acetylcholine receptor (nAChR) and α3β4 nAChR with EC50 of 2.3 μM and 55 μM, respectively. Varenicline dihydrochloride is a potent, full agonist of α7 nAChRs with EC50 of 18 μM. Varenicline is a prescription medication used for smoking cessation. Varenicline (CP 526555) dihydrochloride Chemical Structure
  7. GC26002 Trazodone Trazodone (AF-1161) is a 5-HT 2A/2C receptor antagonist that is used as an antidepressant for treating major depressive disorder and anxiety disorders. Trazodone Chemical Structure
  8. GC25994 Thonzylamine Thonzylamine (Neohetramine) is an antihistamine and anticholinergic drug. Thonzylamine Chemical Structure
  9. GC25898 SB 200646 SB 200646 (SB 200646A) is a potent, selective and oral-active antagonist of 5-HT2B/2C over 5-HT2A receptor with 50 fold selectivity. The pKi for rat 5-HT2C receptor, rat 5-HT2B receptor and rat 5-HT2A receptor are 6.9, 7.5 and 5.2, respectively. SB 200646 has electrophysiological and anxiolytic properties in vivo. SB 200646 Chemical Structure
  10. GC25785 Promethazine Promethazine is a potent histamine H1 receptor antagonist. Promethazine is a medication used in the management and treatment of allergic conditions, nausea and vomiting, motion sickness, and sedation. Promethazine exhibits antiparasitic properties. Promethazine Chemical Structure
  11. GC25756 Pirenperone Pirenperone (R-47456, R-50656), a quinazoline derivative, is a selective antagonist of SR-2A (5-HT2 serotonin receptor) when employed in low doses. Pirenperone behaves like a typical neuroleptic when used in higher doses (greater than 0.1 mg/kg). Pirenperone Chemical Structure
  12. GC25708 Paroxetine mesylate Paroxetine Mesylate(BRL-29060A mesylate,FG-7051 mesylate) is the mesylate salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties. Paroxetine mesylate Chemical Structure
  13. GC25618 Maropitant citrate Maropitant citrate Chemical Structure
  14. GC25583 Lobelin sulphate Lobelin sulphate (Lobeline sulfate, Bantron) is an alkaloid that has actions similar to nicotine on nicotinic cholinergic receptors but is less potent. It has a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation. Lobelin sulphate Chemical Structure
  15. GC25571 Levocetirizine Levocetirizine (LCZ, (R)-Cetirizine), the R-enantiomer of cetirizine, is an antagonist of histamine H(1) receptor. Levocetirizine Chemical Structure
  16. GC25569 Lerisetron Lerisetron (F 0930, F 0930RS) is a 5-HT3 receptor antagonist with IC50 of 0.81μM. Lerisetron Chemical Structure
  17. GC25566 L-DAB HBR L-DAB HBR Chemical Structure
  18. GC25563 Lasmiditan succinate Lasmiditan succinate (COL-144, LY573144) is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (Ki=2.21 nM) without vasoconstrictor activity. Lasmiditan succinate Chemical Structure
  19. GC25531 Isonipecotic acid Isonipecotic acid (4-Piperidinecarboxylic acid, 4-Carboxypiperidine, Hexahydroisonicotinic acid) is a heterocyclic compound that mainly acts as a GABAA receptor partial agonist. Isonipecotic acid Chemical Structure
  20. GC25434 Frovatriptan Succinate Frovatriptan Succinate(SB 209509 Succinate,VML 251 Succinate) is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors. Frovatriptan Succinate Chemical Structure
  21. GC25387 Ethyl (triphenylphosphoranylidene) acetate Ethyl (triphenylphosphoranylidene) acetate (Triphenylcarbethoxymethylenephosphorane, (Carbethoxymethylene)triphenylphosphorane) may act as an inhibitor of cholinesterase that inhibits AChE and BChE. Ethyl (triphenylphosphoranylidene) acetate Chemical Structure
  22. GC25259 Cisapride hydrate Cisapride (Propulsid, Alimix, Propulsin, Enteropride, Kinestase) acts directly as a selective serotonin 5-HT4 receptor agonist with IC50 of 0.483 μM. And It also acts indirectly as a parasympathomimetic. Cisapride hydrate Chemical Structure
  23. GC25253 Cinitapride Hydrogen Tartrate Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors Cinitapride Hydrogen Tartrate Chemical Structure
  24. GC25136 Betazole Dihydrochloride Betazole Dihydrochloride (Ametazole, 2-(3-Pyrazolyl)ethanamine) is a histamine H2 agonist used clinically to test gastric secretory function. Betazole Dihydrochloride Chemical Structure
  25. GC25060 Amitriptyline Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. Amitriptyline is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. This product is a waxy solid. Amitriptyline Chemical Structure
  26. GC68438 AMPA receptor modulator-3 AMPA receptor modulator-3 Chemical Structure
  27. GC68423 Indomethacin-d4 Methyl Ester Indomethacin-d4 Methyl Ester Chemical Structure
  28. GC68422 Choline-d4 chloride Choline-d4 chloride Chemical Structure
  29. GC68420 Propionylpromazine-d6 hydrochloride Propionylpromazine-d6 hydrochloride Chemical Structure
  30. GC68410 (S)-Mirtazapine-d3 (S)-Mirtazapine-d3 Chemical Structure
  31. GC68409 Cetirizine D8 Cetirizine D8 Chemical Structure
  32. GC68383 (R)-Preclamol (R)-Preclamol Chemical Structure
  33. GC68377 OAB-14 OAB-14 Chemical Structure
  34. GC68364 Flibanserin-d4-1 Flibanserin-d4-1 Chemical Structure
  35. GC68363 SEN177 SEN177 Chemical Structure
  36. GC68335 N-Demethyl MK-6884 N-Demethyl MK-6884 Chemical Structure
  37. GC68330 Histamine-α,α,β,β-d4 dihydrochloride Histamine-α,α,β,β-d4 dihydrochloride Chemical Structure
  38. GC68328 3-Hydroxy agomelatine-d3 3-Hydroxy agomelatine-d3 Chemical Structure
  39. GC68326 Ipratropium-d3 bromide Ipratropium-d3 bromide Chemical Structure
  40. GC68323 Flurbiprofen-d5 Flurbiprofen-d5 Chemical Structure
  41. GC68307 Fluphenazine-d8 dihydrochloride Fluphenazine-d8 dihydrochloride Chemical Structure
  42. GC68299 Simtuzumab Simtuzumab Chemical Structure
  43. GC68210 (+)-Norfenfluramine (+)-Norfenfluramine Chemical Structure
  44. GC68206 Propionylpromazine Propionylpromazine Chemical Structure
  45. GC68016 COX-2-IN-6 COX-2-IN-6 Chemical Structure
  46. GC68014 Seliforant Seliforant Chemical Structure
  47. GC67996 TPA-023B TPA-023B Chemical Structure
  48. GC67995 Ketotifen-d3 fumarate Ketotifen-d3 fumarate Chemical Structure
  49. GC67989 (S)-Mirtazapine (S)-Mirtazapine Chemical Structure
  50. GC67979 MK-6884 MK-6884 Chemical Structure
  51. GC67944 Cetirizine D4 Cetirizine D4 Chemical Structure
  52. GC67937 (R)-Mirtazapine (R)-Mirtazapine Chemical Structure
  53. GC67923 Renzapride Renzapride Chemical Structure
  54. GC67922 Zelquistinel Zelquistinel Chemical Structure
  55. GC67882 VU6028418 VU6028418 Chemical Structure
  56. GC67752 Pimozide-d4-1 Pimozide-d4-1 Chemical Structure
  57. GC67705 Naxagolide Naxagolide Chemical Structure
  58. GC52514 Arachidonic Acid-d11 ethyl ester An internal standard for the quantification of arachidonic acid ethyl ester Arachidonic Acid-d11 ethyl ester Chemical Structure
  59. GC52507 Orexin A amide (bovine, human, mouse, rat) (trifluoroacetate salt) A hypothalamic neuropeptide Orexin A amide (bovine, human, mouse, rat) (trifluoroacetate salt) Chemical Structure
  60. GC52505 Ganglioside GT1b (bovine) (sodium salt) A sphingolipid Ganglioside GT1b (bovine) (sodium salt) Chemical Structure
  61. GC52502 Peptide YY (3-36) (trifluoroacetate salt) A satiety hormone Peptide YY (3-36) (trifluoroacetate salt) Chemical Structure
  62. GC52500 Dynorphin A (trifluoroacetate salt) An endogenous opioid receptor agonist Dynorphin A (trifluoroacetate salt) Chemical Structure
  63. GC52498 NGB 2904 (hydrochloride) A selective D3 antagonist NGB 2904 (hydrochloride) Chemical Structure
  64. GC52497 Lactosylceramide (porcine RBC) A sphingolipid Lactosylceramide (porcine RBC) Chemical Structure
  65. GC52496 Sulfatide (bovine) (sodium salt) A mixture of isolated bovine sulfatides Sulfatide (bovine) (sodium salt) Chemical Structure
  66. GC52495 AF-353 (hydrochloride) A dual P2X3 and P2X2/3 receptor antagonist AF-353 (hydrochloride) Chemical Structure
  67. GC52494 β-Endorphin (rat) (trifluoroacetate salt) An opioid neuropeptide β-Endorphin (rat) (trifluoroacetate salt) Chemical Structure
  68. GC52493 Glucosylceramide (bovine buttermilk) A sphingolipid Glucosylceramide (bovine buttermilk) Chemical Structure
  69. GC52492 Globotriaosylceramide (hydroxy) (porcine RBC) A sphingolipid Globotriaosylceramide (hydroxy) (porcine RBC) Chemical Structure
  70. GC52491 Globotriaosylceramide (non-hydroxy) (porcine RBC) A sphingolipid Globotriaosylceramide (non-hydroxy) (porcine RBC) Chemical Structure
  71. GC52487 Ganglioside GM4 (chicken egg) (ammonium salt) A sphingolipid Ganglioside GM4 (chicken egg) (ammonium salt) Chemical Structure
  72. GC52486 Ceramide Phosphoethanolamine (bovine) A sphingolipid Ceramide Phosphoethanolamine (bovine) Chemical Structure
  73. GC52484 Purified Ganglioside Mixture (bovine) (ammonium salt) A mixture of purified bovine gangliosides Purified Ganglioside Mixture (bovine) (ammonium salt) Chemical Structure
  74. GC52483 Fucosylated Ganglioside GM1 (porcine) (ammonium salt) A sphingolipid Fucosylated Ganglioside GM1 (porcine) (ammonium salt) Chemical Structure
  75. GC52477 Corynoxine (hydrochloride) An indole alkaloid Corynoxine (hydrochloride) Chemical Structure
  76. GC52476 Bax Inhibitor Peptide V5 (trifluoroacetate salt) A Bax inhibitor Bax Inhibitor Peptide V5 (trifluoroacetate salt) Chemical Structure
  77. GC52473 NVP-AAM077 An NMDA receptor antagonist NVP-AAM077 Chemical Structure
  78. GC52453 Orexin A (17-33) (human, mouse, rat, bovine) (trifluoroacetate salt) A peptide orexin receptor 1 agonist Orexin A (17-33) (human, mouse, rat, bovine) (trifluoroacetate salt) Chemical Structure
  79. GC52449 Spadin (trifluoroacetate salt) An inhibitor of K2P2.1/TREK1 Spadin (trifluoroacetate salt) Chemical Structure
  80. GC52438 CGRP (8-37) (mouse, rat) (trifluoroacetate salt) A CGRP receptor antagonist CGRP (8-37) (mouse, rat) (trifluoroacetate salt) Chemical Structure
  81. GC52424 Bradykinin Fragment (1-5) (trifluoroacetate salt) A metabolite of bradykinin Bradykinin Fragment (1-5) (trifluoroacetate salt) Chemical Structure
  82. GC52421 (±)-10-hydroxy-12(Z)-Octadecenoic Acid-d5 An internal standard for the quantification of (±)-10-hydroxy-12(Z)-octadecenoic acid (±)-10-hydroxy-12(Z)-Octadecenoic Acid-d5 Chemical Structure
  83. GC52419 MOG (35-55) (mouse, rat) (trifluoroacetate salt) An MOG antigen peptide MOG (35-55) (mouse, rat) (trifluoroacetate salt) Chemical Structure
  84. GC52414 [Ala17]-MCH (trifluoroacetate salt) An MCH-derived peptide and MCH receptor agonist [Ala17]-MCH (trifluoroacetate salt) Chemical Structure
  85. GC52412 TT-232 (trifluoroacetate salt) A synthetic peptide derivative of somatostatin TT-232 (trifluoroacetate salt) Chemical Structure
  86. GC52411 Exendin-4 (5-39) amide (trifluoroacetate salt) An antagonist of the GLP-1 receptor Exendin-4 (5-39) amide (trifluoroacetate salt) Chemical Structure
  87. GC52409 BAM-22P (8-22) (human, mouse, rat, bovine) (trifluoroacetate salt) A neuropeptide and MRGPRX1 agonist BAM-22P (8-22) (human, mouse, rat, bovine) (trifluoroacetate salt) Chemical Structure
  88. GC52407 BAM-22P (human, mouse, rat, bovine) (trifluoroacetate salt) A neuropeptide BAM-22P (human, mouse, rat, bovine) (trifluoroacetate salt) Chemical Structure
  89. GC52403 Ivermectin-d2 An internal standard for the quantification of ivermectin Ivermectin-d2 Chemical Structure
  90. GC52399 Norephedrine-d5 (hydrochloride) An internal standard for the quantification of norephedrine Norephedrine-d5 (hydrochloride) Chemical Structure
  91. GC52391 306-O12B-3 An ionizable cationic lipidoid 306-O12B-3 Chemical Structure
  92. GC52390 Spexin 1 (human, mouse, rat, bovine) (acetate) An endogenous peptide and agonist of GAL2 and GAL3 Spexin 1 (human, mouse, rat, bovine) (acetate) Chemical Structure
  93. GC52389 Caveolin-1 (82-101) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) A synthetic peptide fragment of caveolin-1 Caveolin-1 (82-101) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) Chemical Structure
  94. GC52388 [D-Lys3]-GHRP-6 (trifluoroacetate salt) An antagonist of GHS-R1a [D-Lys3]-GHRP-6 (trifluoroacetate salt) Chemical Structure
  95. GC52385 Myelin Basic Protein (85-99) Peptide Antagonist (trifluoroacetate salt) An MBP (85-99) antagonist Myelin Basic Protein (85-99) Peptide Antagonist (trifluoroacetate salt) Chemical Structure
  96. GC52382 Nogo-66 (1-40) (human, mouse, rat) (trifluoroacetate salt) A peptide fragment of Nogo-A Nogo-66 (1-40) (human, mouse, rat) (trifluoroacetate salt) Chemical Structure
  97. GC52354 Tertiapin Q (trifluoroacetate salt) A peptide derivative of tertiapin Tertiapin Q (trifluoroacetate salt) Chemical Structure
  98. GC52342 P4pal10 (trifluoroacetate salt) A PAR4 and FPR2 antagonist and an FFAR2 agonist P4pal10 (trifluoroacetate salt) Chemical Structure
  99. GC52332 Arimoclomol A co-inducer of heat shock proteins Arimoclomol Chemical Structure
  100. GC52331 Lactoyl Phenylalanine A secondary metabolite Lactoyl Phenylalanine Chemical Structure
  101. GC52329 Betamethasone-d5 An internal standard for the quantification of betamethasone Betamethasone-d5 Chemical Structure

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