Neuroscience

Neuroscience
Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides).
Targets for Neuroscience
- 5-HT Receptor(488)
- AChR(54)
- AChE(103)
- Alzheimer(80)
- Amyloid β(114)
- BACE(4)
- CGRP (23)
- COX(271)
- DAPK(3)
- Dopamine Receptor(281)
- GABA Receptor(218)
- Gap Junction(18)
- GluR(120)
- Histamine(3)
- Histamine Receptor(211)
- mPEGS-1(4)
- Muscarinic Receptor(43)
- Neuroscience Peptides(48)
- Nicotinic Receptor(66)
- P2 Receptor(2)
- P2X7 receptor(4)
- SSRIs(8)
- Substance P/NK1 Receptor(23)
- NMDA(2)
- Cholecystokinin Receptor(22)
- GPR139(1)
- mAChR(127)
- MCHR1 (GPR24)(15)
- Neurokinin Receptor(55)
- iGluR(125)
- nAChR(58)
- Beta-secretase(24)
- CaMK(28)
- Dopamine Transporter(17)
- Monoamine Oxidase(70)
- Serotonin Transporter(50)
- Behavioral Neuroscience(234)
- DREADD(0)
- Huntington(10)
- Neuroendocrinology(33)
- Neuroprotection(70)
- Ophthalmology(105)
- Pain Research(139)
- Parkinson(44)
- Seizure Disorders(62)
- Prion(6)
Products for Neuroscience
- Cat.No. Product Name Information
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GC63267
α-Chaconine
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GC40262
α-Humulene
α-Humulene is a sesquiterpene that has been found in C.
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GC41499
α-Phellandrene
α-Phellandrene is a cyclic monoterpene that has been found in various plants, including Cannabis, and has diverse biological activities.
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GC10873
α-Spinasterol
TRPV1 antagonist
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GC63615
α-Thujone
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GC49467
β-Aescin
A triterpenoid saponin with diverse biological activities
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GC63273
β-Amyloid (1-14),mouse,rat
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GC63274
β-Amyloid (1-42), (rat/mouse) (TFA)
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GC37984
β-Amyloid (1-42), rat
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GC61394
β-Amyloid (1-42), rat TFA
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GC37991
β-Amyloid 15-21
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GC34944
β-CGRP, human TFA
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GC41623
β-Elemonic Acid
β-Elemonic acid is a triterpene isolated from Boswellia (Burseraceae) that exhibits anticancer activity.
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GC45234
β-Endorphin (1-27) (human) (trifluoroacetate salt)
β-Endorphin (1-27) is an endogenous peptide that binds to μ-, δ-, and κ-opioid receptors (Kis = 5.31, 6.17, and 39.82 nM, respectively, in COS-1 cells expressing rat receptors).
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GC45236
β-Endorphin (rat)
β-Endorphin (β-EP) is an endogenous opioid neuropeptide with diverse biological activities.
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GC40105
βARK1 Inhibitor
βARK1 inhibitor is an inhibitor of G protein-coupled receptor kinase 2/β-adrenergic receptor kinase 1 (GRK2/βARK1; IC50 = 126 μM).
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GC38010
γ-Aminobutyric acid
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GC10426
α-Bungarotoxin
α7 nAChR antagonist
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GC10872
α-Conotoxin AuIB
Selective antagonist of α3β4 nicotinic acetylcholine receptors
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GC13644
α-Conotoxin EI
Selective antagonist of neuromuscular nicotinic receptors α1β1γδ
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GC14353
α-Conotoxin ImI
Nicotinic receptor antagonist
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GC14296
α-Conotoxin PIA
Selective antagonist of α6-containing nicotinic receptors
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GC10368
α-Conotoxin PnIA
Selective antagonist of α3β2 nAChR receptors
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GC11577
α-Methyl-5-hydroxytryptamine maleate
5-HT2B receptor agonist
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GC34242
β-Amyloid (1-42), rat TFA
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GC31146
β-Amyloid (10-35), amide
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GC31129
β-Amyloid 1-16 (Amyloid β-Protein (1-16))
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GC31171
β-Amyloid 1-28 (Amyloid β-Protein (1-28))
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GC30325
β-Amyloid 22-35 (Amyloid β-Protein (22-35))
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GC31137
β-Amyloid 29-40 (Amyloid beta-protein(29-40))
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GC31179
β-Amyloid 31-35
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GC11449
β-CCB
benzodiazepine receptor ligand
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GC33595
β-CGRP, human (Human β-CGRP)
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GC18033
γDGG
glutamate receptor antagonist
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GC41657
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (hydrobromide)
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (6,7-ADTN) is a dopamine receptor agonist (EC50s = 3.5 and 0.65 μM in rat striatal and nucleus accumbens homogenates, respectively).
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GC41658
(±)-2-hydroxy Ibuprofen
(±)-2-hydroxy Ibuprofen is a metabolite of ibuprofen .
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GC62726
(±)-Amiflamine
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GC12774
(±)-Anatoxin A fumarate
nicotinic agonist
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GC60394
(±)-Duloxetine hydrochloride
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GC14410
(±)-Epibatidine
nicotinic agonist
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GC49515
(±)-Ibuprofen-d3 (sodium salt)
An internal standard for the quantification of (±)-ibuprofen
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GC45278
(±)-Ketoprofen-d3
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GC12699
(±)-LY 395756
ligand for mGlu2 and mGlu3 receptor
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GC16735
(±)-McN 5652
5-HT uptake inhibitor
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GC14834
(±)-Nipecotic acid
GABA uptake inhibitor
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GC41676
(±)-Nornicotine
(±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist.
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GC49482
(±)-Nornicotine-d4
An internal standard for the quantification of (±)-nornicotine
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GC12394
(±)-trans-ACPD
metabotropic glutamate receptors agonist
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GC11128
(±)-Vesamicol hydrochloride
acetylcholine transport inhibitor
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GC41685
(±)-WIN 55,212 (mesylate)
(±)-WIN 55,212-2 is a potent aminoalkylindole cannabinoid (CB) receptor agonist with a Ki value of 62.3 and 3.3 nM for human recombinant central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, respectively.
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GC41213
(±)10-HDHA
(±)10-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.
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GC41214
(±)11-HDHA
(±)11-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.
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GC40467
(±)11-HETE
(±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid.
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GC40802
(±)12(13)-DiHOME
(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.
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GC41191
(±)13(14)-EpDPA
Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers.
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GC41192
(±)13-HDHA
(±)13-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.
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GC41193
(±)14-HDHA
(±)14-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.
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GC41194
(±)16(17)-EpDPA
EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators.
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GC41196
(±)16-HDHA
(±)16-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.
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GC41197
(±)17-HDHA
(±)17-HDHA is an autoxidation product of docosahexaenoic acid in vitro.
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GC41199
(±)19(20)-EpDPA
EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators.
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GC41202
(±)4-HDHA
(±)4-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.
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GC41203
(±)7(8)-EpDPA
Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina.
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GC41204
(±)7-HDHA
(±)7-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.
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GC41205
(±)8-HDHA
(±)8-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.
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GC14400
(±)-Huperzine A
AChE inhibitor
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GC33544
(±)-Methotrimeprazine (D6) (dl-Methotrimeprazine D6)
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GC31026
(±)-Tazifylline
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GN10155
(+)- Corydaline
Extracted from Corydalis yanhusuo W.T. Wang tubers;Store the product in sealed, cool and dry condition
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GC13156
(+)-AJ 76 hydrochloride
Dopamine receptor antagonist
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GC12432
(+)-Anabasine hydrochloride
neuronal nicotinic ACh receptor partial agonist
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GN10745
(+)-Bicuculline
GABAA receptor antagonist,competitve and classical
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GC34954
(+)-Borneol
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GN10605
(+)-Catechin hydrate
Antioxidant flavonoid with various bioactivities
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GC34957
(+)-Cevimeline hydrochloride hemihydrate
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GN10654
(+)-Corynoline
Extracted from corydalis sheareri S. Moore;Store the product in sealed,cool and dry condition
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GC45263
(+)-D-threo-PDMP (hydrochloride)
(+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP.
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GC30933
(+)-Kavain
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GC10736
(+)-Muscarine iodide
Muscarinic acetylcholine receptor agonist
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GC30848
(+)-PD 128907 hydrochloride
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GC34959
(+)-Sparteine
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GC11062
(+)-Tubocurarine chloride
nicotinic acetylcholine receptor antagonist
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GC12870
(+)-UH 232 maleate
D2 antagonist
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GC11049
(+/-)-Sulfinpyrazone
platelet COX inhibitor
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GC38677
(-)-α-Pinene
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GC45244
(-)-(α)-Kainic Acid (hydrate)
A potent central nervous system stimulant for induction of seizures
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GC31084
(-)-(S)-B-973B
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GC10065
(-)-Bicuculline methiodide
GABAA receptor antagonist
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GC16857
(-)-Bicuculline methobromide
GABAA antagonist
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GC15636
(-)-Bicuculline methochloride
GABAA antagonist
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GC40842
(-)-Catechin
(-)-Catechin is a diastereoisomer of catechin having a trans 2S,3R configuration at the chiral center.
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GC32957
(-)-Catechin gallate ((-)-Catechin 3-gallate)
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GC17470
(-)-Cotinine
α3/α6β2 nAChR activator
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GC18343
(-)-CP 55,940
(-)-CP 55,940 is a potent and non-selective cannabinoid (CB) receptor agonist with Ki values of 0.5 to 5 and 0.69 to 2.8 nM for CB1 and CB2 receptors, respectively.
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GC16081
(-)-epicatechin
inducer of pancreatic β-cell regeneration
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GC10603
(-)-epicatechin gallate
major catechin in green tea
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GC11965
(-)-Huperzine A
NMDA receptor antagonist/AChE inhibitor
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GC34949
(-)-Isocorypalmine
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GC45250
(-)-L-threo-PDMP (hydrochloride)
(-)-L-threo-PDMP is an enhancer of ganglioside biosynthesis.
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GC14157
(-)-Lobeline hydrochloride
nicotinic receptor partial agonist