Carboxypeptidase
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A carboxypeptidase (CP) is an enzyme involved in the catabolism of proteins that cleaves amino acids from the C-terminal of proteins or large peptides through rapid hydrolysis at the last stages of protein cleavage. So far thirteen mammalian CPs encoded by thirteen known members of the metallocarboxypeptidase gene family and one human-specific CP (CPA3) have been identified. Based primarily on amino acid sequence similarities, metallocarboxypeptidases are divided into two subfamilies, including CPA/B family (CPA1, CPA2, CPB, MK-CPA and KPU) and CPN/E family (CPE/H, CPM, CPN, CPD, CPZ, CPX1, CPX2 and AEBP1). All members in CPA/B family are approximately 34-36 kDa proteins of optimal pH=7; while all members in CPN/E family range in size and pH optima.
Products Related to Carboxypeptidase(10)
- GC118042-Guanidinoethylmercaptosuccinic AcidCAS: 77482-44-1Purity: >98%
2-Guanidinoethylmercaptosuccinic Acid (2-Guanidinoethylmercaptosuccinic acid) is a potent specific inhibitor of carboxypeptidase B-like processing enzyme (encephalin convertase) with the Ki value of 8.8 nM.
- GC13467PMPA (NAALADase inhibitor)CAS: 173039-10-6Purity: >98.00%
A potent inhibitor of GCP II/NAALADase
- GC35608Carboxypeptidase G2 (CPG2) InhibitorCAS: 192203-60-4Purity: >98.00%
Carboxypeptidase G2 (CPG2) Inhibitor is a novel Carboxypeptidase G2 (CPG2) Inhibitor, Antitumor agents.
- GC35741CPA inhibitorCAS: 223532-02-3Purity: >99.50%
CPA inhibitor (Carboxypeptidase inhibitor; compound 5) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM.
- GC604712-Benzylsuccinic acidCAS: 884-33-3Purity: >98.00%
2-Benzylsuccinic acid (DL-Benzylsuccinic acid) is an potent inhibitor of carboxypeptidase A (CPA).
- GC63338GCPII-IN-1 TFACAS: 1269794-89-9Purity: >98%
GCPII-IN-1 TFA is a glutamate carboxypeptidase II (GCPII, or PSMA) inhibitor scaffold with a Ki of 44.3 nM.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC11804 | 2-Guanidinoethylmercaptosuccinic Acid | 77482-44-1 | >98% | |
2-Guanidinoethylmercaptosuccinic Acid (2-Guanidinoethylmercaptosuccinic acid) is a potent specific inhibitor of carboxypeptidase B-like processing enzyme (encephalin convertase) with the Ki value of 8.8 nM. | ||||
| GC13467 | PMPA (NAALADase inhibitor) | 173039-10-6 | >98.00% | |
A potent inhibitor of GCP II/NAALADase | ||||
| GC17937 | 2-MPPA | 254737-29-6 | >98.00% | |
glutamate carboxypeptidase II (GCP II) inhibitor | ||||
| GC18065 | ZJ 43 | 723331-20-2 | >98% | |
| GC35608 | Carboxypeptidase G2 (CPG2) Inhibitor | 192203-60-4 | >98.00% | |
Carboxypeptidase G2 (CPG2) Inhibitor is a novel Carboxypeptidase G2 (CPG2) Inhibitor, Antitumor agents. | ||||
| GC35741 | CPA inhibitor | 223532-02-3 | >99.50% | |
CPA inhibitor (Carboxypeptidase inhibitor; compound 5) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM. | ||||
| GC60471 | 2-Benzylsuccinic acid | 884-33-3 | >98.00% | |
2-Benzylsuccinic acid (DL-Benzylsuccinic acid) is an potent inhibitor of carboxypeptidase A (CPA). | ||||
| GC63338 | GCPII-IN-1 TFA | 1269794-89-9 | >98% | |
GCPII-IN-1 TFA is a glutamate carboxypeptidase II (GCPII, or PSMA) inhibitor scaffold with a Ki of 44.3 nM. | ||||
| GC72702 | Mergetpa | 77102-28-4 | >95.00% | |
Mergetpa is a carboxypeptidase inhibitor used to block the conversion of kinins and B2 receptor antagonists to metabolites lacking the C-terminal arginine. | ||||
| GC79578 | PrCP-7414 | 1252037-41-4 | >99.50% | |
PrCP-7414 is a prolyl carboxypeptidase ( PRCP ) inhibitor. | ||||