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Proteases

Proteases is a general term for a class of enzymes that hydrolyze protein peptide chains. According to the way they degrade polypeptides, they are divided into two categories: endopeptidases and telopeptidases. The former can cut the large molecular weight polypeptide chain from the middle to form prions and peptones with smaller molecular weights; the latter can be divided into carboxypeptidase and aminopeptidase, which respectively remove the peptide from the free carboxyl terminus or free amino terminus of the polypeptide one by one. Chain hydrolysis produces amino acids.

A general term for a class of enzymes that hydrolyze peptide bonds in proteins. According to the way they hydrolyze polypeptides, they can be divided into endopeptidases and exopeptidases. Endopeptidase cleaves the interior of the protein molecule to form smaller molecular weight peptones and peptones. Exopeptidase hydrolyzes peptide bonds one by one from the end of the free amino group or carboxyl group of protein molecules, and frees amino acids, the former is aminopeptidase and the latter is carboxypeptidase. Proteases can be classified into serine proteases, sulfhydryl proteases, metalloproteases and aspartic proteases according to their active centers and optimum pH. According to the optimum pH value of its reaction, it is divided into acidic protease, neutral protease and alkaline protease. The proteases used in industrial production are mainly endopeptidases.

Proteases are widely found in animal offal, plant stems and leaves, fruits and microorganisms. Microbial proteases are mainly produced by molds and bacteria, followed by yeast and actinomycetes.

Enzymes that catalyze the hydrolysis of proteins. There are many kinds, the important ones are pepsin, trypsin, cathepsin, papain and subtilisin. Proteases have strict selectivity for the reaction substrates they act on. A protease can only act on certain peptide bonds in protein molecules, such as the peptide bonds formed by the hydrolysis of basic amino acids catalyzed by trypsin. Proteases are widely distributed, mainly in the digestive tract of humans and animals, and are abundant in plants and microorganisms. Due to limited animal and plant resources, the industrial production of protease preparations is mainly prepared by fermentation of microorganisms such as Bacillus subtilis and Aspergillus terrestris.

Products for  Proteases

  1. Cat.No. Product Name Information
  2. GC68478 Bictegravir sodium Bictegravir sodium  Chemical Structure
  3. GC68468 MPO-IN-3 MPO-IN-3  Chemical Structure
  4. GC68464 ALDH1A3-IN-1 ALDH1A3-IN-1  Chemical Structure
  5. GC68462 ALDH1A3-IN-2 ALDH1A3-IN-2  Chemical Structure
  6. GC68453 ITMN 4077 ITMN 4077  Chemical Structure
  7. GC68450 Hsp90-IN-17 hydrochloride Hsp90-IN-17 hydrochloride  Chemical Structure
  8. GC68426 17a-Hydroxypregnenolone-d3 17a-Hydroxypregnenolone-d3  Chemical Structure
  9. GC68421 L-Aspartic acid-13C4,15N L-Aspartic acid-13C4,15N  Chemical Structure
  10. GC68417 Homovanillic acid-d5 Homovanillic acid-d5  Chemical Structure
  11. GC68415 Glycolic acid-d2 Glycolic acid-d2  Chemical Structure
  12. GC68414 (Rac)-Atropine-d3 (Rac)-Atropine-d3  Chemical Structure
  13. GC68399 Isolindleyin Isolindleyin  Chemical Structure
  14. GC68395 L-Isoleucine-d10 L-Isoleucine-d10  Chemical Structure
  15. GC68387 FGN849 FGN849  Chemical Structure
  16. GC68384 DL-Mevalonolactone-d7 DL-Mevalonolactone-d7  Chemical Structure
  17. GC68382 L-Cysteine-1-13C L-Cysteine-1-13C  Chemical Structure
  18. GC68380 Sarcosine-15N Sarcosine-15N  Chemical Structure
  19. GC68375 Cholic acid-13C Cholic acid-13C  Chemical Structure
  20. GC68374 5a-Pregnane-3,20-dione-d6 5a-Pregnane-3,20-dione-d6  Chemical Structure
  21. GC68351 DL-Homocysteine-d4 DL-Homocysteine-d4  Chemical Structure
  22. GC68329 Normetanephrine-d3 hydrochloride Normetanephrine-d3 hydrochloride  Chemical Structure
  23. GC68324 3-Methoxytyramine-d4 hydrochloride 3-Methoxytyramine-d4 hydrochloride  Chemical Structure
  24. GC68310 S-Adenosyl-L-methionine-d3 S-Adenosyl-L-methionine-d3  Chemical Structure
  25. GC68302 AS-Inclisiran AS-Inclisiran  Chemical Structure
  26. GC68228 5-Nitro-1,10-phenanthroline 5-Nitro-1,10-phenanthroline  Chemical Structure
  27. GC68218 Mepazine Mepazine  Chemical Structure
  28. GC68216 L-Valine-1-13C L-Valine-1-13C  Chemical Structure
  29. GC68215 Glycine-1-13C Glycine-1-13C  Chemical Structure
  30. GC68214 DL-Alanine-13C-1 DL-Alanine-13C-1  Chemical Structure
  31. GC68150 BC-1382 BC-1382  Chemical Structure
  32. GC68149 L-Serine-15N L-Serine-15N  Chemical Structure
  33. GC68148 L-Tyrosine-d2 L-Tyrosine-d2  Chemical Structure
  34. GC68143 L-Methionine-1-13C L-Methionine-1-13C  Chemical Structure
  35. GC68142 D-Phenylalanine-d5 D-Phenylalanine-d5  Chemical Structure
  36. GC68097 Acetyl-L-carnitine-d3 hydrochloride Acetyl-L-carnitine-d3 hydrochloride  Chemical Structure
  37. GC68082 3,4,5-Trimethoxyphenylacetic acid 3,4,5-Trimethoxyphenylacetic acid  Chemical Structure
  38. GC68055 4-Hydroxyphenyl acetate 4-Hydroxyphenyl acetate  Chemical Structure
  39. GC68053 L-Tyrosine-1-13C L-Tyrosine-1-13C  Chemical Structure
  40. GC68052 Pyruvic acid 13C sodium Pyruvic acid 13C sodium  Chemical Structure
  41. GC68049 L-Aspartic acid-1,4-13C2 L-Aspartic acid-1,4-13C2  Chemical Structure
  42. GC68042 DL-Homocystine-3,3,3',3',4,4,4',4'-d8 DL-Homocystine-3,3,3',3',4,4,4',4'-d8  Chemical Structure
  43. GC68038 L-Tyrosine D4 L-Tyrosine D4  Chemical Structure
  44. GC68022 L-Methionine-15N L-Methionine-15N  Chemical Structure
  45. GC68020 L-Glutamic acid-1-13C L-Glutamic acid-1-13C  Chemical Structure
  46. GC68013 CDE-096 CDE-096  Chemical Structure
  47. GC68009 KS106 KS106  Chemical Structure
  48. GC68008 GÜ2602 GÜ2602  Chemical Structure
  49. GC67997 Aminopeptidase-IN-1 Aminopeptidase-IN-1  Chemical Structure
  50. GC67993 (Rac)-Cotinine-d4 (Rac)-Cotinine-d4  Chemical Structure
  51. GC67992 MLT-747 MLT-747  Chemical Structure
  52. GC67988 6-Hydroxybenzbromarone 6-Hydroxybenzbromarone  Chemical Structure
  53. GC67978 Paltimatrectinib Paltimatrectinib  Chemical Structure
  54. GC67976 D-Glucose-13C D-Glucose-13C  Chemical Structure
  55. GC67975 Hexacosanoic acid-d4-1 Hexacosanoic acid-d4-1  Chemical Structure
  56. GC67973 L-Alanine-13C2 L-Alanine-13C2  Chemical Structure
  57. GC67952 Hippuric acid-d5 Hippuric acid-d5  Chemical Structure
  58. GC67951 5-Hydroxytryptophol-d4 5-Hydroxytryptophol-d4  Chemical Structure
  59. GC67947 Triolein 13C3 Triolein 13C3  Chemical Structure
  60. GC67942 Stearic acid-d3 Stearic acid-d3  Chemical Structure
  61. GC67918 MPO-IN-1 MPO-IN-1  Chemical Structure
  62. GC67916 Palmitic acid-d4 Palmitic acid-d4  Chemical Structure
  63. GC67911 L-Serine-1-13C L-Serine-1-13C  Chemical Structure
  64. GC67910 L-Citrulline-13C L-Citrulline-13C  Chemical Structure
  65. GC67902 3-Amino-2-oxazolidinone-d4 3-Amino-2-oxazolidinone-d4  Chemical Structure
  66. GC67898 GLS-1-IN-1 GLS-1-IN-1  Chemical Structure
  67. GC67835 Glycocholic acid sodium Glycocholic acid sodium  Chemical Structure
  68. GC67782 ALDH1A2-IN-1 ALDH1A2-IN-1  Chemical Structure
  69. GC67781 Diaplasinin Diaplasinin  Chemical Structure
  70. GC67771 GSK321 GSK321  Chemical Structure
  71. GC67766 Abiraterone sulfate Abiraterone sulfate  Chemical Structure
  72. GC67761 (Z)-10-Hydroxynortriptyline-d3 (Z)-10-Hydroxynortriptyline-d3  Chemical Structure
  73. GC67751 Berotralstat dihydrochloride Berotralstat dihydrochloride  Chemical Structure
  74. GC67731 S-(2-Carboxypropyl)-L-cysteine S-(2-Carboxypropyl)-L-cysteine  Chemical Structure
  75. GC67701 Ulodesine Ulodesine  Chemical Structure
  76. GC67697 XZ426 XZ426  Chemical Structure
  77. GC67693 Saccharopine hydrochloride Saccharopine hydrochloride  Chemical Structure
  78. GC67682 (S,S)-GSK321 (S,S)-GSK321  Chemical Structure
  79. GC67670 L-Cysteine S-sulfate sodium hydrate L-Cysteine S-sulfate sodium hydrate  Chemical Structure
  80. GC52478 Telmisartan Acyl-β-D-Glucuronide (hydrate) A major metabolite of telmisartan Telmisartan Acyl-β-D-Glucuronide (hydrate)  Chemical Structure
  81. GC52413 5-Aminosalicylic Acid-d7 An internal standard for the quantification of 5-aminosalicylic acid 5-Aminosalicylic Acid-d7  Chemical Structure
  82. GC52368 DL-Sulforaphane Glutathione A metabolite of sulforaphane DL-Sulforaphane Glutathione  Chemical Structure
  83. GC52355 BimS BH3 (51-76) (human) (trifluoroacetate salt) A Bim-derived peptide BimS BH3 (51-76) (human) (trifluoroacetate salt)  Chemical Structure
  84. GC52324 3-(3-Hydroxyphenyl)propionic Acid sulfate A metabolite of certain phenols and glycosides 3-(3-Hydroxyphenyl)propionic Acid sulfate  Chemical Structure
  85. GC52306 Pentadecanoyl-L-carnitine (chloride) A CB receptor agonist Pentadecanoyl-L-carnitine (chloride)  Chemical Structure
  86. GC52290 (R)-HTS-3 An inhibitor of LPCAT3 (R)-HTS-3  Chemical Structure
  87. GC52256 CAY10794 An inhibitor of DGAT-1 CAY10794  Chemical Structure
  88. GC52236 Nonadecanoyl-L-carnitine-d3 (chloride) An internal standard for the quantification of nonadecanoyl-L-carnitine Nonadecanoyl-L-carnitine-d3 (chloride)  Chemical Structure
  89. GC52231 Heptadecanoyl-L-carnitine-d3 (chloride) An internal standard for the quantification of heptadecanoyl-L-carnitine Heptadecanoyl-L-carnitine-d3 (chloride)  Chemical Structure
  90. GC52227 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone An active metabolite of various polyphenols 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone  Chemical Structure
  91. GC52223 Nonadecanoyl-L-carnitine (chloride) A long-chain acylcarnitine Nonadecanoyl-L-carnitine (chloride)  Chemical Structure
  92. GC52219 Heptadecanoyl-L-carnitine (chloride) A long-chain acylcarnitine Heptadecanoyl-L-carnitine (chloride)  Chemical Structure
  93. GC52214 Nicotinamide riboside-d4 (triflate) An internal standard for the quantification of nicotinamide riboside Nicotinamide riboside-d4 (triflate)  Chemical Structure
  94. GC67659 Palmitoyl coenzyme A lithium Palmitoyl coenzyme A lithium is an acyl-CoA thioester that can be transported into the mitochondrial matrix via the carnitine shuttle system and is involved in β-oxidation. Palmitoyl coenzyme A lithium can also be used as a substrate for sphingosine biosynthesis. Palmitoyl coenzyme A lithium  Chemical Structure
  95. GC67642 Hexanoyl coenzyme A trilithium Hexanoyl coenzyme A trilithium is a hexanoyl-based medium-chain fatty acyl coenzyme A that is present in all organisms. Hexanoyl coenzyme A trilithium can be used as a precursor for cannabinoid biosynthesis and acts as a competitive inhibitor of medium-chain acyl coenzyme A dehydrogenase (MCAD). Hexanoyl coenzyme A trilithium  Chemical Structure
  96. GC67633 Propionyl coenzyme A lithium Propionyl coenzyme A lithium, a coenzyme A derivative of propionic acid, is an important metabolic intermediate formed by the thioester bond between coenzyme A and propionic acid. The breakdown and production of Propionyl coenzyme A lithim is important for the metabolism of organisms. Propionyl coenzyme A lithium  Chemical Structure
  97. GC67624 L-Aspartic aicd disodium L-Aspartic acid disodium is an amino acid, can be used as a suitable prodrug for colon-specific drug deliverly. L-Aspartic aicd disodium  Chemical Structure
  98. GC67535 L-Aspartic acid potassium Aspartic acid potassium is an amino acid, can be used as a suitable prodrug for colon-specific drug deliverly. L-Aspartic acid potassium  Chemical Structure
  99. GC67484 β-Nicotinamide adenine dinucleotide reduced dipotassium β-Nicotinamide adenine dinucleotide reduced dipotassium is an orally active reduced coenzyme. β-Nicotinamide adenine dinucleotide reduced dipotassium is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. β-Nicotinamide adenine dinucleotide reduced dipotassium plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle. β-Nicotinamide adenine dinucleotide reduced dipotassium  Chemical Structure
  100. GC67476 (E/Z)-Sulindac sulfide (E/Z)-Sulindac sulfide is a potent γ-secretase modulator (GSM). (E/Z)-Sulindac sulfide selectively reduces Aβ42 production in favor of shorter Aβ species. (E/Z)-Sulindac sulfide can be used for researching Alzheimer's disease. (E/Z)-Sulindac sulfide  Chemical Structure
  101. GC67473 L-Tartaric acid sodium hydrate L-Tartaric acid (L-(+)-Tartaric acid) sodium hydrate is the enantiomer of D-tartaric acid. L-Tartaric acid is a white crystalline dicarboxylic acid found in many plants, such as grapes, and is one of the main organic acids in wine. L-Tartaric acid sodium hydrate which acts as a flour bulking agent and as a food additive can interact with sodium bicarbonate to produce carbon dioxide. L-Tartaric acid sodium hydrate  Chemical Structure

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