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Proteases

Proteases is a general term for a class of enzymes that hydrolyze protein peptide chains. According to the way they degrade polypeptides, they are divided into two categories: endopeptidases and telopeptidases. The former can cut the large molecular weight polypeptide chain from the middle to form prions and peptones with smaller molecular weights; the latter can be divided into carboxypeptidase and aminopeptidase, which respectively remove the peptide from the free carboxyl terminus or free amino terminus of the polypeptide one by one. Chain hydrolysis produces amino acids.

A general term for a class of enzymes that hydrolyze peptide bonds in proteins. According to the way they hydrolyze polypeptides, they can be divided into endopeptidases and exopeptidases. Endopeptidase cleaves the interior of the protein molecule to form smaller molecular weight peptones and peptones. Exopeptidase hydrolyzes peptide bonds one by one from the end of the free amino group or carboxyl group of protein molecules, and frees amino acids, the former is aminopeptidase and the latter is carboxypeptidase. Proteases can be classified into serine proteases, sulfhydryl proteases, metalloproteases and aspartic proteases according to their active centers and optimum pH. According to the optimum pH value of its reaction, it is divided into acidic protease, neutral protease and alkaline protease. The proteases used in industrial production are mainly endopeptidases.

Proteases are widely found in animal offal, plant stems and leaves, fruits and microorganisms. Microbial proteases are mainly produced by molds and bacteria, followed by yeast and actinomycetes.

Enzymes that catalyze the hydrolysis of proteins. There are many kinds, the important ones are pepsin, trypsin, cathepsin, papain and subtilisin. Proteases have strict selectivity for the reaction substrates they act on. A protease can only act on certain peptide bonds in protein molecules, such as the peptide bonds formed by the hydrolysis of basic amino acids catalyzed by trypsin. Proteases are widely distributed, mainly in the digestive tract of humans and animals, and are abundant in plants and microorganisms. Due to limited animal and plant resources, the industrial production of protease preparations is mainly prepared by fermentation of microorganisms such as Bacillus subtilis and Aspergillus terrestris.

Products for  Proteases

  1. Cat.No. Product Name Information
  2. GC70185 β-Sitostenone β-Sitostenone  Chemical Structure
  3. GC70147 WNK1-IN-1 WNK1-IN-1  Chemical Structure
  4. GC70088 UDP-rhamnose UDP-rhamnose  Chemical Structure
  5. GC70082 UBA5-IN-1 UBA5-IN-1  Chemical Structure
  6. GC70079 Tyrosinase-IN-2 Tyrosinase-IN-2  Chemical Structure
  7. GC70020 TG-2-IN-1 TG-2-IN-1  Chemical Structure
  8. GC70014 Terephthalic acid-13C2 Terephthalic acid-13C2  Chemical Structure
  9. GC69967 Sucrose-d14 Sucrose-d14  Chemical Structure
  10. GC69954 Stearic acid-d7 Stearic acid-d7  Chemical Structure
  11. GC69914 (S)-Malic acid-d3 (S)-Malic acid-d3  Chemical Structure
  12. GC69911 Skp2 inhibitor 1 Skp2 inhibitor 1  Chemical Structure
  13. GC69901 Sitagliptin fenilalanil hydrochloride Sitagliptin fenilalanil hydrochloride  Chemical Structure
  14. GC69900 Sitagliptin fenilalanil Sitagliptin fenilalanil  Chemical Structure
  15. GC69866 SCFSkp2-IN-2 SCFSkp2-IN-2  Chemical Structure
  16. GC69858 Sarcosine-d3 Sarcosine-d3  Chemical Structure
  17. GC69856 Sampatrilat Sampatrilat  Chemical Structure
  18. GC69842 Rugonersen Rugonersen  Chemical Structure
  19. GC69835 RPR132595A hydrochloride RPR132595A hydrochloride  Chemical Structure
  20. GC69824 RO5461111 RO5461111  Chemical Structure
  21. GC69777 PU-H54 PU-H54  Chemical Structure
  22. GC69739 Propionyl-DL-carnitine chloride Propionyl-DL-carnitine chloride  Chemical Structure
  23. GC69672 PCSK9-IN-12 PCSK9-IN-12  Chemical Structure
  24. GC69671 PCSK9-IN-11 PCSK9-IN-11  Chemical Structure
  25. GC69670 PCSK9-IN-10 PCSK9-IN-10  Chemical Structure
  26. GC69651 p-Aminophenylmercuric acetate p-Aminophenylmercuric acetate  Chemical Structure
  27. GC69607 O-Demethyl Lenvatinib hydrochloride O-Demethyl Lenvatinib hydrochloride  Chemical Structure
  28. GC69585 Normetanephrine Normetanephrine  Chemical Structure
  29. GC69583 Norartocarpetin Norartocarpetin  Chemical Structure
  30. GC69581 Nonadecanoic acid-d37 Nonadecanoic acid-d37  Chemical Structure
  31. GC69578 NNK-d4 NNK-d4  Chemical Structure
  32. GC69576 N-Methylnicotinamide-d4 N-Methylnicotinamide-d4  Chemical Structure
  33. GC69575 N-methyl-N-dithiocarboxyglucamine sodium N-methyl-N-dithiocarboxyglucamine sodium  Chemical Structure
  34. GC69564 N-Isovalerylglycine-d9 N-Isovalerylglycine-d9  Chemical Structure
  35. GC69554 NFF-3 TFA NFF-3 TFA  Chemical Structure
  36. GC69551 N-Ethylmaleimide-d5 N-Ethylmaleimide-d5  Chemical Structure
  37. GC69522 Myristic acid-d5 Myristic acid-d5  Chemical Structure
  38. GN10810 Cordycepin Cordycepin  Chemical Structure
  39. GN10801 Senkyunolide I Senkyunolide I  Chemical Structure
  40. GN10792 Caffeic acid Caffeic acid  Chemical Structure
  41. GN10783 (R) Ginsenoside Rh2 (R) Ginsenoside Rh2  Chemical Structure
  42. GN10764 Homovanillic acid Homovanillic acid  Chemical Structure
  43. GN10686 Ginsenoside Rh2 Ginsenoside Rh2  Chemical Structure
  44. GN10676 Palmitic acid

    A long-chain saturated fatty acid

    Palmitic acid  Chemical Structure
  45. GN10669 Glucosamine sulfate Glucosamine sulfate  Chemical Structure
  46. GN10668 Coenzyme Q10 Coenzyme Q10  Chemical Structure
  47. GN10629 5,7-dihydroxychromone 5,7-dihydroxychromone  Chemical Structure
  48. GN10623 Cholic acid Cholic acid  Chemical Structure
  49. GN10622 Shikimic acid Shikimic acid  Chemical Structure
  50. GN10578 Polygalacic acid Polygalacic acid  Chemical Structure
  51. GN10564 Ecdysterone Ecdysterone  Chemical Structure
  52. GN10558 L-Carnitine inner salt L-Carnitine inner salt  Chemical Structure
  53. GN10555 Bilirubin Bilirubin  Chemical Structure
  54. GN10554 Phytic acid Phytic acid  Chemical Structure
  55. GN10552 Syringic acid Syringic acid  Chemical Structure
  56. GN10545 Escin IA Escin IA  Chemical Structure
  57. GN10540 Fumalic acid Fumalic acid  Chemical Structure
  58. GN10518 Chitosamine hydrochloride Chitosamine hydrochloride  Chemical Structure
  59. GN10506 Umbelliferone Umbelliferone  Chemical Structure
  60. GN10494 Astragaloside IV Astragaloside IV  Chemical Structure
  61. GN10492 Allantoin Allantoin  Chemical Structure
  62. GN10489 Hyodeoxycholic acid Hyodeoxycholic acid  Chemical Structure
  63. GN10473 Ginkgolide C Ginkgolide C  Chemical Structure
  64. GN10470 Eriodictyol Eriodictyol  Chemical Structure
  65. GN10423 Lipoic acid Lipoic acid  Chemical Structure
  66. GN10382 Xylitol Xylitol  Chemical Structure
  67. GN10360 Morroniside Morroniside  Chemical Structure
  68. GN10359 Stigmasterol Stigmasterol  Chemical Structure
  69. GN10349 Ergosterol Ergosterol  Chemical Structure
  70. GN10347 Nicotinamide (Vitamin B3)

    Nicotinamide is an inhibitor of poly(ADP-ribose) polymerase (PARP-1) enzymes.

    Nicotinamide (Vitamin B3)  Chemical Structure
  71. GN10342 Chondroitin sulfate Chondroitin sulfate  Chemical Structure
  72. GN10306 Folic acid Folic acid  Chemical Structure
  73. GN10304 Taxifolin Taxifolin  Chemical Structure
  74. GN10290 Norcantharidin Norcantharidin  Chemical Structure
  75. GN10289 Trigonelline Trigonelline  Chemical Structure
  76. GN10285 Theobromine Theobromine  Chemical Structure
  77. GN10269 Wedelolactone Wedelolactone  Chemical Structure
  78. GN10267 Loureirin B Loureirin B  Chemical Structure
  79. GN10227 Sodium Demethylcantharidate Sodium Demethylcantharidate  Chemical Structure
  80. GN10211 Salvianolic acid A Salvianolic acid A  Chemical Structure
  81. GN10184 Oleanolic acid Oleanolic acid  Chemical Structure
  82. GN10158 Baicalein Baicalein  Chemical Structure
  83. GN10146 Butane diacid Butane diacid  Chemical Structure
  84. GN10091 Schaftoside Schaftoside  Chemical Structure
  85. GN10073 Arbutin Arbutin  Chemical Structure
  86. GN10072 Daidzin Daidzin  Chemical Structure
  87. GN10063 Arctigenin Arctigenin  Chemical Structure
  88. GN10062 5-HTP 5-HTP  Chemical Structure
  89. GN10055 Mulberroside A Mulberroside A  Chemical Structure
  90. GN10040 Dehydrocorydaline Dehydrocorydaline  Chemical Structure
  91. GA11306 H-D-Ser-OH An NMDA co-agonist H-D-Ser-OH  Chemical Structure
  92. GA10825 Ac-His-OH Ac-His-OH Ac-His-OH  Chemical Structure
  93. GA11230 H-Pyr-OH H-Pyr-OH  Chemical Structure
  94. GA10879 H-DL-Nva-OH H-DL-Nva-OH  Chemical Structure
  95. GA10799 H-Nle-OH H-Nle-OH  Chemical Structure
  96. GA10943 H-Tyr(3-NO2)-OH H-Tyr(3-NO2)-OH  Chemical Structure
  97. GA10205 H-Tyr(3-I)-OH H-Tyr(3-I)-OH  Chemical Structure
  98. GA11341 H-Hyp-OH A chiral building block H-Hyp-OH  Chemical Structure
  99. GA10611 H-HoArg-OH H-HoArg-OH  Chemical Structure
  100. GA10664 H-Dab?HBr H-Dab?HBr  Chemical Structure
  101. GA11190 H-Cit-OH H-Cit-OH  Chemical Structure

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