Proteases
Proteases is a general term for a class of enzymes that hydrolyze protein peptide chains. According to the way they degrade polypeptides, they are divided into two categories: endopeptidases and telopeptidases. The former can cut the large molecular weight polypeptide chain from the middle to form prions and peptones with smaller molecular weights; the latter can be divided into carboxypeptidase and aminopeptidase, which respectively remove the peptide from the free carboxyl terminus or free amino terminus of the polypeptide one by one. Chain hydrolysis produces amino acids.
A general term for a class of enzymes that hydrolyze peptide bonds in proteins. According to the way they hydrolyze polypeptides, they can be divided into endopeptidases and exopeptidases. Endopeptidase cleaves the interior of the protein molecule to form smaller molecular weight peptones and peptones. Exopeptidase hydrolyzes peptide bonds one by one from the end of the free amino group or carboxyl group of protein molecules, and frees amino acids, the former is aminopeptidase and the latter is carboxypeptidase. Proteases can be classified into serine proteases, sulfhydryl proteases, metalloproteases and aspartic proteases according to their active centers and optimum pH. According to the optimum pH value of its reaction, it is divided into acidic protease, neutral protease and alkaline protease. The proteases used in industrial production are mainly endopeptidases.
Proteases are widely found in animal offal, plant stems and leaves, fruits and microorganisms. Microbial proteases are mainly produced by molds and bacteria, followed by yeast and actinomycetes.
Enzymes that catalyze the hydrolysis of proteins. There are many kinds, the important ones are pepsin, trypsin, cathepsin, papain and subtilisin. Proteases have strict selectivity for the reaction substrates they act on. A protease can only act on certain peptide bonds in protein molecules, such as the peptide bonds formed by the hydrolysis of basic amino acids catalyzed by trypsin. Proteases are widely distributed, mainly in the digestive tract of humans and animals, and are abundant in plants and microorganisms. Due to limited animal and plant resources, the industrial production of protease preparations is mainly prepared by fermentation of microorganisms such as Bacillus subtilis and Aspergillus terrestris.
Products for Proteases
- Caspase(83)
- Aminopeptidase(18)
- ACE(67)
- Calpains(11)
- Carboxypeptidase(8)
- Cathepsin(49)
- DPP-4(18)
- Elastase(21)
- Gamma Secretase(42)
- HCV Protease(35)
- HSP(92)
- HIV Integrase(27)
- HIV Protease(32)
- MMP(166)
- NS3/4a protease(4)
- Serine Protease(11)
- Thrombin(39)
- Urokinase(2)
- Other Proteases(15)
- Tyrosinases(41)
- 15-PGDH(1)
- Acetyl-CoA Carboxylase(11)
- Acyltransferase(53)
- Aldehyde Dehydrogenase (ALDH)(24)
- Aminoacyl-tRNA Synthetase(9)
- ATGL(1)
- Dipeptidyl Peptidase(46)
- Drug Metabolite(451)
- E1/E2/E3 Enzyme(80)
- Endogenous Metabolite(1492)
- FABP(8)
- Farnesyl Transferase(21)
- Glutaminase(14)
- Glutathione Peroxidase(13)
- Isocitrate Dehydrogenase (IDH)(25)
- Lactate Dehydrogenase(16)
- Lipoxygenase(227)
- Mitochondrial Metabolism(196)
- NEDD8-activating Enzyme(6)
- Neprilysin(12)
- PAI-1(11)
- Ser/Thr Protease(35)
- Tryptophan Hydroxylase(11)
- Xanthine Oxidase(16)
- MALT1(10)
- PCSK9(1)
- Cat.No. Product Name Information
-
GC70185
β-Sitostenone
-
GC70147
WNK1-IN-1
-
GC70088
UDP-rhamnose
-
GC70082
UBA5-IN-1
-
GC70079
Tyrosinase-IN-2
-
GC70020
TG-2-IN-1
-
GC70014
Terephthalic acid-13C2
-
GC69967
Sucrose-d14
-
GC69954
Stearic acid-d7
-
GC69914
(S)-Malic acid-d3
-
GC69911
Skp2 inhibitor 1
-
GC69901
Sitagliptin fenilalanil hydrochloride
-
GC69900
Sitagliptin fenilalanil
-
GC69866
SCFSkp2-IN-2
-
GC69858
Sarcosine-d3
-
GC69856
Sampatrilat
-
GC69842
Rugonersen
-
GC69835
RPR132595A hydrochloride
-
GC69824
RO5461111
-
GC69777
PU-H54
-
GC69739
Propionyl-DL-carnitine chloride
-
GC69672
PCSK9-IN-12
-
GC69671
PCSK9-IN-11
-
GC69670
PCSK9-IN-10
-
GC69651
p-Aminophenylmercuric acetate
-
GC69607
O-Demethyl Lenvatinib hydrochloride
-
GC69585
Normetanephrine
-
GC69583
Norartocarpetin
-
GC69581
Nonadecanoic acid-d37
-
GC69578
NNK-d4
-
GC69576
N-Methylnicotinamide-d4
-
GC69575
N-methyl-N-dithiocarboxyglucamine sodium
-
GC69564
N-Isovalerylglycine-d9
-
GC69554
NFF-3 TFA
-
GC69551
N-Ethylmaleimide-d5
-
GC69522
Myristic acid-d5
-
GN10810
Cordycepin
-
GN10801
Senkyunolide I
-
GN10792
Caffeic acid
-
GN10783
(R) Ginsenoside Rh2
-
GN10764
Homovanillic acid
-
GN10686
Ginsenoside Rh2
-
GN10676
Palmitic acid
A long-chain saturated fatty acid
-
GN10669
Glucosamine sulfate
-
GN10668
Coenzyme Q10
-
GN10629
5,7-dihydroxychromone
-
GN10623
Cholic acid
-
GN10622
Shikimic acid
-
GN10578
Polygalacic acid
-
GN10564
Ecdysterone
-
GN10558
L-Carnitine inner salt
-
GN10555
Bilirubin
-
GN10554
Phytic acid
-
GN10552
Syringic acid
-
GN10545
Escin IA
-
GN10540
Fumalic acid
-
GN10518
Chitosamine hydrochloride
-
GN10506
Umbelliferone
-
GN10494
Astragaloside IV
-
GN10492
Allantoin
-
GN10489
Hyodeoxycholic acid
-
GN10473
Ginkgolide C
-
GN10470
Eriodictyol
-
GN10423
Lipoic acid
-
GN10382
Xylitol
-
GN10360
Morroniside
-
GN10359
Stigmasterol
-
GN10349
Ergosterol
-
GN10347
Nicotinamide (Vitamin B3)
Nicotinamide is an inhibitor of poly(ADP-ribose) polymerase (PARP-1) enzymes.
-
GN10342
Chondroitin sulfate
-
GN10306
Folic acid
-
GN10304
Taxifolin
-
GN10290
Norcantharidin
-
GN10289
Trigonelline
-
GN10285
Theobromine
-
GN10269
Wedelolactone
-
GN10267
Loureirin B
-
GN10227
Sodium Demethylcantharidate
-
GN10211
Salvianolic acid A
-
GN10184
Oleanolic acid
-
GN10158
Baicalein
-
GN10146
Butane diacid
-
GN10091
Schaftoside
-
GN10073
Arbutin
-
GN10072
Daidzin
-
GN10063
Arctigenin
-
GN10062
5-HTP
-
GN10055
Mulberroside A
-
GN10040
Dehydrocorydaline
-
GA11306
H-D-Ser-OH
An NMDA co-agonist
-
GA10825
Ac-His-OH
Ac-His-OH
-
GA11230
H-Pyr-OH
-
GA10879
H-DL-Nva-OH
-
GA10799
H-Nle-OH
-
GA10943
H-Tyr(3-NO2)-OH
-
GA10205
H-Tyr(3-I)-OH
-
GA11341
H-Hyp-OH
A chiral building block
-
GA10611
H-HoArg-OH
-
GA10664
H-Dab?HBr
-
GA11190
H-Cit-OH