Prostaglandin D2 (PGD2) evokes its effects through two receptors, DP1 and CRTH2/DP2. The activation of DP2 leads to eosinophil chemotaxis, activation, and degranulation as well as recruitment of basophils and lymphocytes and, as a result, is important in allergic inflammatory disease. CAY10648 is an intermediate used in the synthesis of potent DP2 receptor antagonists based on a novel spiro-indolinone compound.
CAY10648
Catalog No.: GC43186Purity:>98.00%
Prostaglandin D2 (PGD2) evokes its effects through two receptors, DP1 and CRTH2/DP2.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 916048-02-7
1mgIn Stock
$112.00
1
5mgIn Stock
$499.00
1
10mgIn Stock
$886.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 1mg | $112.00 | In Stock | 1 | |
| 5mg | $499.00 | In Stock | 1 | |
| 10mg | $886.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>98.00%Appearance:A solid
Chemical Properties
CAS No.
916048-02-7
SMILES
ClC1=CC=C(N(C(C23CCNC3=O)=O)CC(OC(C)(C)C)=O)C2=C1
Molecular Formula
C17H19ClN2O4
Molecular Weight
350.8
Solubility
DMF: 5 mg/ml,DMSO: 10 mg/ml,DMSO:PBS(pH 7.2) (1:2): .25 mg/ml,Ethanol: 1 mg/ml
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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