GLPBio

CD00509

Catalog No.: GC74677Purity:>98.00%
CD00509 is a Tdp1 inhibitor, with an IC50 value of 0.71 μM.

Products are for research use only. Not for human use. We do not sell to patients.


CD00509
Cas No.: 27430-18-8
1mgIn Stock
$20.00
1
5mgIn Stock
$45.00
1
10mgIn Stock
$67.00
1
25mgIn Stock
$116.00
1
50mgIn Stock
$172.00
1
100mgIn Stock
$261.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

CD00509 is a Tdp1 inhibitor, with an IC50 value of 0.71 μM. CD00509 can sensitize breast cancer cells to Camptothecin . CD00509 has anti-tumor activity.

References:
[1]. Laev SS, et al. Tyrosyl-DNA phosphodiesterase inhibitors: Progress and potential. Bioorg Med Chem. 2016 Nov 1;24(21):5017-5027.

Product Documents

Purity:>98.00%Appearance:A solid

Chemical Properties

CAS No.
27430-18-8
Molecular Formula
C9H6N2O3S
Molecular Weight
222.22
Solubility
DMSO : 12.5 mg/mL (56.25 mM; Need ultrasonic)
Storage
4°C, sealed storage, away from moisture and light
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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