PDE
PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.
Products for PDE
- Cat.No. Product Name Information
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GC34984
(R)-(-)-Rolipram
-
GC50321
(S)-C33
Potent PDE9 inhibitor
-
GC13956
2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide
phosphodiesterase 7 (PDE7) inhibitor
-
GC60024
3-O-Methylquercetin
-
GC50419
A 33
Potent and selective PDE4B inhibitor
-
GC41269
Acetildenafil
Acetildenafil is an analog of the phosphodiesterase inhibitor sildenafil, named for a substitution of an acetyl group for a sulfonyl group.
-
GC31213
AMG 579
-
GC10859
Amino Tadalafil
analog of tadalafil, a potent inhibitor of phosphodiesterase 5
-
GC12764
Aminophylline
Pan-PDE inhibitor
-
GC42792
Amrinone
Amrinone is an inhibitor of phosphodiesterase 3 (PDE3; IC50 = 19.5 μM).
-
GC11472
AN-2728
PDE4 inhibitor,anti-inflammatory compound
-
GC31728
AN3199
-
GC11273
Anagrelide HCl
Thrombocytopenic agent
-
GC10420
Apremilast (CC-10004)
PDE4 inhibitor
-
GC62403
ATX inhibitor 5
-
GC30390
Autotaxin modulator 1
-
GC38890
Autotaxin-IN-3
-
GC16856
Avanafil
PDE5 inhibitor
-
GC60063
Ayanin
-
GC19343
Balipodect
TAK-063 is a highly potent, selective and orally active PDE10A inhibitor with IC50 of 0.30 nM; >15000-fold selectivity over other PDEs.
-
GC64703
BAY 2666605
-
GC19512
Bay 60-7550
Bay 60-7550 is a potent and selective PDE2 inhibitor with a Ki of 3.8 nM
-
GC30923
BAY 73-6691 ((R)-BAY 73-6691)
-
GC30915
BAY 73-6691 racemate
-
GC16048
BC 11-38
Selective PDE11 inhibitor
-
GC60074
BI-2545
-
GC19068
BI-409306
BI-409306 is a potent and selective PDE9A inhibitor, with an IC50 of 52 nM, and shows weak activity against other PDEs, such as PDE1A (IC50, 1.4 uM), PDE1C (IC50, 1.0 uM), PDE2A, PDE3A, PDE4B, PDE5A, PDE6AB, PDE7A, and PDE10A (IC50 all > 10 uM).
-
GC35543
BPN14770
-
GC15472
BRL 50481
PDE7 inhibitor,potent and selective
-
GC35565
Bucladesine calcium salt
A membrane permeable selective activator of PKA
-
GC10944
Butein
Protein kinase inhibitor
-
GC31915
BW-A 78U
-
GC61508
CALP2 TFA
-
GC33337
CDC801
-
GC16632
CDP 840 hydrochloride
PDE4 inhibitor,potent and selective
-
GC31786
CI-1044 (PD-189659)
-
GC17598
Cilomilast
Potent PDE4 inhibitor
-
GC10109
Cilostamide
type III phosphodiesterase (PDE3) inhibitor
-
GC15890
Cilostazol
PDE3 inhibitor
-
GC10542
CP 80633
PDE4 inhibitor
-
GC19111
CP671305
CP671305 is a potent, orally active, selective inhibitor of phosphodiesterase-4-D, and possesses high activities.
-
GC34895
D159687
-
GC13076
Deltarasin
KRAS-PDEδ interaction inhibitor
-
GC12060
Deltarasin hydrochloride
inhibitor of KRAS-PDEδ interaction, potent and selective
-
GC35837
Deltasonamide 2 (TFA)
-
GC35838
Deltasonamide 2 hydrochloride
-
GC12824
Dibutyryl-cAMP, sodium salt
Cell-permeable cAMP analog that activates cAMP-dependent protein kinases
-
GC62589
Difamilast
-
GC17673
Dipyridamole
PDE inhibitor
-
GC62234
DNMDP
-
GC13444
Doxofylline
PDE inhibitor
-
GC13652
Dyphylline
Pan-PDE inhibitor
-
GC10796
Eggmanone
selective inhibitor of PDE4
-
GC10004
Enoximone
type III phosphodiesterase (PDE3) inhibitor
-
GC62466
Ensifentrine
-
GC39288
ent-Tadalafil
-
GC30437
ER21355
-
GC12771
Etazolate hydrochloride
PDE-4 inhibitor and selective GABA-A receptor modulator
-
GC64005
FPFT-2216
-
GC62977
FR-229934
-
GN10231
Fraxin;Fraxoside; Paviin
Extracted from White wax;Suitability:Hot water and hot ethanol;Store the product in sealed,cool and dry condition
-
GC43715
Furamidine (hydrochloride)
Furamidine is a cell-permeable inhibitor of protein arginine methyltransferase 1 (PRMT1) that is selective for PRMT1 over PRMT5, PRMT6, and PRMT4/coactivator-associated arginine methyltransferase 1 (CARM1) (IC50s = 9.4, 166, 283, and >400 μM, respectively).
-
GC15189
Gisadenafil besylate
PDE5 inhibitor
-
GC41486
Glaucine
Glaucine is an alkaloid originally isolated from G.
-
GC19168
GLPG1690
GLPG1690 is a first-in-class autotaxin (ATX) inhibitor, with an IC50 of 131 nM and Ki of 15 nM.
-
GC36187
GSK 256066 Trifluoroacetate
-
GC14180
GSK256066
PDE4-inhibitor,selective and highly potent
-
GC14697
HA 130
autotaxin inhibitor
-
GC10869
HA-155
autotaxin inhibitor
-
GC64012
Hcyb1
-
GC11730
IBMX
Phosphodiesterase inhibitor
-
GC13275
Ibudilast
inhibitor of PDE4
-
GN10278
Icariin
A PDE5 inhibitor
-
GC32643
ICI 153110
-
GC11313
ICI 63197
PDE4 inhibitor
-
GC60199
Ilexsaponin B2
-
GC13191
Irsogladine
PDE4 inhibitor
-
GC33878
Irsogladine maleate (Dicloguamine maleate)
-
GC30811
ITI214
-
GC30841
ITI214 free base
-
GC32633
K134 (OPC33509)
-
GC31258
L791943
-
GC32529
LAS-31180
-
GC62525
LEO 39652
-
GC38921
Lirimilast
-
GC36474
Lodenafil
-
GC36475
Lodenafil carbonate
-
GC36540
Mardepodect
-
GC36541
Mardepodect hydrochloride
-
GC16849
MBCQ
cGMP-specific phosphodiesterase PDE V inhibitor
-
GC13657
Mesopram
PDE4 inhibitor, orally active
-
GC14868
Milrinone
PDE-3 inhibitor
-
GC36616
Mirodenafil
-
GC36617
Mirodenafil dihydrochloride
-
GC16072
ML-030
PDE4 inhibitor
-
GC12878
MMPX
calmodulin-sensitive cyclic GMP phosphodiesterase inhibitor
-
GC39539
Moracin M
-
GC11684
MY-5445
PDE5 inhibitor
-
GC63308
N-Desmethyl Sildenafil-d8
-
GC11072
Nortadalafil
PDE5 inhibitor