GLPBio

CellFluor™ GST

Catalog No.: GC92062Synonyms: Cell Fluor™ Glutathione S-Transferase; DNs-Rh; bis-DNs-Rh
COASDSData Sheet
CellFluor GST is a cell-permeable quenched fluorescent probe for the detection of pan-glutathione S-transferase activity in adherent or suspension cells, cell or tissue lysates, or purified enzyme preparations.

Products are for research use only. Not for human use. We do not sell to patients.

CellFluor™ GST
Cas No.: 1028386-82-4
0.1 µmolIn Stock
$699.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

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Description

CellFluor? GST is a cell-permeable quenched fluorescent probe for the detection of pan-glutathione S-transferase (GST) activity in adherent or suspension cells, cell or tissue lysates, or purified enzyme preparations. It is composed of rhodamine 110 protected by the GST substrate dinitrobenzenesulfonamide (DNB).1,2 Upon deprotection by GSTs, rhodamine 110 is released, and its fluorescence can be quantified using excitation/emission maxima of 496/520 nm, respectively.

References:
[1]. Shibata, A., Furukawa, K., Abe, H., et al.Rhodamine-based fluorogenic probe for imaging biological thiolBioorg. Med. Chem. Lett.18(7)2246-2249(2008).
[2]. ?lander, J., Johansson, K., Heuser, V.D., et al.Characterization of a new fluorogenic substrate for microsomal glutathione transferase 1Anal. Biochem.390(1)52-56(2009).

Product Documents

Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1028386-82-4
Synonyms
Cell Fluor™ Glutathione S-Transferase; DNs-Rh; bis-DNs-Rh
Chemical Name
9-(2-carboxyphenyl)-3,6-bis[[(2,4-dinitrophenyl)sulfonyl]amino]-xanthylium, inner salt
SMILES
O=S(C(C([N+]([O-])=O)=C1)=CC=C1[N+]([O-])=O)(NC2=CC([O+]=C3C(C=CC(NS(C(C([N+]([O-])=O)=C4)=CC=C4[N+]([O-])=O)(=O)=O)=C3)=C5C6=C(C([O-])=O)C=CC=C6)=C5C=C2)=O
Molecular Formula
C32H18N6O15S2
Molecular Weight
790.6
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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