GLPBio

CIL62

Catalog No.: GC60707Purity:>95.00%
COASDSData Sheet
CIL62 is a caspase-3/7-independent cell death inducer. The mechanism of action of CIL62 is Necrostatin-1 dependent cell death.

Products are for research use only. Not for human use. We do not sell to patients.

CIL62
Cas No.: 117593-36-9
10mM (in 1mL DMSO)In Stock
$113.00
1
1mgIn Stock
$53.00
1
5mgIn Stock
$134.00
1
10mgIn Stock
$201.00
1
25mgIn Stock
$327.00
1
50mgIn Stock
$453.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    31, 1291–1307 (2021)

Description

CIL62 is a caspase-3/7-independent cell death inducer. The mechanism of action of CIL62 is Necrostatin-1 dependent cell death[1].

19 µM (5 µg/mL) Necrostatin-1 suppresses CIL62, but CIL62 is not suppressed by the ferroptosis inducers (antioxidants or iron-chelators)[1].

[1]. Kenichi Shimada, et al. Global Survey of Cell Death Mechanisms Reveals Metabolic Regulation of Ferroptosis. Nat Chem Biol. 2016 Jul;12(7):497-503.

Product Documents

Purity:>95.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
117593-36-9
SMILES
O=C1C(C(C2=CC=C(O)C=C2O)C3=C(CC(C)(C)CC3=O)O4)=C4CC(C)(C)C1
Molecular Formula
C23H26O5
Molecular Weight
382.45
Solubility
DMSO: 125 mg/mL (326.84 mM)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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