Lipid CP-LC-1447 is an ionizable cationic amino lipid derived from homocysteine, a naturally occurring amino acid. This lipid has demonstrated an efficient delivery and high protein expression of different kinds of RNA (mRNA, cRNA and saRNA)?in vivo. Moreover, using a typical LNP formulation (IL/Ch/DOPE/PEG: 50/38.5/10/1.5), it has shown to induce specific spleen targeting much more efficiently that other commercial alternatives through IV injection, with no signs of toxicity.
CP-LC-1447
Catalog No.: GC92084Purity:>95.00%
Lipid CP-LC-1447 is an ionizable cationic amino lipid derived from homocysteine, a naturally occurring amino acid.
Products are for research use only. Not for human use. We do not sell to patients.
5 mgIn Stock
$209.00
1
10 mgIn Stock
$333.00
1
25 mgIn Stock
$731.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 5 mg | $209.00 | In Stock | 1 | |
| 10 mg | $333.00 | In Stock | 1 | |
| 25 mg | $731.00 | In Stock | 1 |
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com
Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>95.00%Appearance:A solution in ethanol
Chemical Properties
Chemical Name
dioctyl 3,3'-((8-((1-((2-(1H-imidazol-1-yl)ethyl)amino)-1-oxo-4-((3-oxo-3-(tridecyloxy)propyl)thio)butan-2-yl)amino)-8-oxooctane-1,3-diyl)bis(sulfanediyl))dipropionate
SMILES
O=C(NCCN1C=CN=C1)C(CCSCCC(OCCCCCCCCCCCCC)=O)NC(CCCCC(CCSCCC(OCCCCCCCC)=O)SCCC(OCCCCCCCC)=O)=O
Molecular Formula
C55H100N4O8S3
Molecular Weight
1041.6
Solubility
Ethanol: Soluble: ≥10 mg/ml
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
Reviews
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