GLPBio

CRM1

CRM1 (i.e. XPO-1, Exportin-1) is a mammalian ubiquitous protein that mediates the transport of protein and RNA across the nuclear membrane to the cytoplasm.

Products Related to CRM1(8)

  • GC12142 structure
    GC12142KPT-276
    CAS: 1421919-75-6
    Purity: >98%

    inhibitor of nuclear export (SINE) and CRM1, orally bioavailable

  • GC12467 structure
    GC12467KPT-330
    CAS: 1393477-72-9
    Purity: >98.00%

    KPT-330 (Selinexor) is an orally active selective inhibitor of nuclear export (SINE) compound that inhibits the nuclear export protein XPO1 (also known as CRM1).

  • GC14517 structure
    GC14517KPT-185
    CAS: 1333151-73-7
    Purity: >98%

    CRM1 inhibitor,selective and irrversible

  • GC10954 structure
    GC10954Leptomycin B
    CAS: 87081-35-4
    Purity: >99.50%

    Leptomycin B (LMB) is an inhibitor of chromosome region maintenance 1 (CRM1) that is one of the nuclear protein exporters.

  • GC15777 structure
    GC15777Verdinexor (KPT-335)
    CAS: 1392136-43-4
    Purity: >98%

    XPO1/CRM1 inhibitor

  • GC18345 structure
    GC18345Leptomycin A
    CAS: 87081-36-5
    Purity: >98%

    Leptomycin A is an inhibitor of CRM1 (exportin 1) that blocks CRM1 interaction with nuclear export signals, preventing the nuclear export of a broad range of proteins.

  • GC19213 structure
    GC19213Eltanexor Z-isomer
    CAS: 1642300-78-4
    Purity: >98%

    KPT-8602 Z-isomer is the less active isomer of KPT-8602.

  • GC19466 structure
    GC19466Eltanexor (KPT-8602)
    CAS: 1642300-52-4
    Purity: >99.50%

    Eltanexor (KPT-8602) is an orally active exportin-1 (XPO1) inhibitor (EC 50 = 60.9nM).