CSF-1R

CSF-1R is a tyrosine kinase transmembrane receptor for colony stimulating factor 1. It is a cytokine that regulates proliferation and differentiation of macrophages.

Products Related to CSF-1R(3)

GC17286 GW2580
CAS: 870483-87-7
Purity: >98.00%
GW2580 is a selective and orally bioavailable inhibitor of colony-stimulating factor-1 receptor (CSF-1R), with an IC 50 of 30nM, and completely inhibits the human c-Fms kinase at 0.06μM.
GC12222 Pexidartinib (PLX3397)
CAS: 1029044-16-3
Purity: >98.00%
Pexidartinib (PLX3397)is a potent, orally active, selective, and ATP-competitive CSF1R and c-Kit inhibitor, with IC 50 values of 0.02μM and 0.01μM, respectively.
GC12539 BLZ945
CAS: 953769-46-5
Purity: >99.50%
BLZ945 (BLZ945) is a potent, selective and brain-penetrant CSF-1R (c-Fms) inhibitor with an IC50 of 1 nM, showing more than 1,000-fold selectivity against its closest receptor tyrosine kinase homologs.

Category Product List
Catalog No.	Product Name	CAS No.	Purity
GC17286	GW2580	870483-87-7	>98.00%
GC17286	GW2580 is a selective and orally bioavailable inhibitor of colony-stimulating factor-1 receptor (CSF-1R), with an IC 50 of 30nM, and completely inhibits the human c-Fms kinase at 0.06μM.
GC12222	Pexidartinib (PLX3397)	1029044-16-3	>98.00%
GC12222	Pexidartinib (PLX3397)is a potent, orally active, selective, and ATP-competitive CSF1R and c-Kit inhibitor, with IC 50 values of 0.02μM and 0.01μM, respectively.
GC12539	BLZ945	953769-46-5	>99.50%
GC12539	BLZ945 (BLZ945) is a potent, selective and brain-penetrant CSF-1R (c-Fms) inhibitor with an IC50 of 1 nM, showing more than 1,000-fold selectivity against its closest receptor tyrosine kinase homologs.