GLPBio

Dapaconazole

Catalog No.: GC62304Purity:>98.50%
COASDSData Sheet
Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 μM.

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Dapaconazole
Cas No.: 1269726-67-1
10mM (in 1mL DMSO)In Stock
$248.00
1
1mgIn Stock
$90.00
1
5mgIn Stock
$225.00
1
10mgIn Stock
$360.00
1
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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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Description

Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 μM[1].

Dapaconazole inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 ± 0.3 μM[1].

Dapaconazole (20 mg/kg; p.o.) shows that the bioavailability is 97.3 %[1].

[1]. Juliana SP, et al. Pharmacokinetics of Dapaconazole, A Novel Antifungal Agent, in Beagle Dogs and Inhibition of Cytochrome P450 Family 51. J Eur Acad Dermatol Venereol. 2018 Jun 10.

Product Documents

Purity:>98.50%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1269726-67-1
Molecular Formula
C19H15Cl2F3N2O
Molecular Weight
415.24
Solubility
DMSO : 100 mg/mL (240.82 mM; Need ultrasonic)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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