A666 peptide TFA is a highly selective prestin ligand. A666 peptide TFA enables active drug delivery (e.g., dexamethasone) to outer hair cells (OHCs). A666 peptide TFA is promising for research of cisplatin-induced ototoxicity protection and sensorineural hearing loss interventions [1].
References:
[1]. Wang X, et al. A666-conjugated nanoparticles target prestin of outer hair cells preventing cisplatin-induced hearing loss. Int J Nanomedicine. 2018 Nov 14;13:7517-7531.
References:
[1]. Wang X, et al. A666-conjugated nanoparticles target prestin of outer hair cells preventing cisplatin-induced hearing loss. Int J Nanomedicine. 2018 Nov 14;13:7517-7531.