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CAY10486 (Synonyms: 4Hydroxycinnamic acid (Lphenylalanine methyl ester) amide)

Katalog-Nr.GC40869

Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis.

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CAY10486 Chemische Struktur

Cas No.: 615264-52-3

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of approximately 60 µM. It also inhibits copper-mediated oxidation of low density lipoproteins by about 28% at a concentration of 3 µM.

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