FITC -dextran sulfate (MW 4kDa) is a dextran sulfate labeled with FITC, with an average molecular weight of 4 kDa. FITC -dextran sulfate (MW 4kDa) serves as an anionic macromolecular tracer. FITC -dextran sulfate (MW 4kDa) can be used for permeability studies [1].
In Vitro, FITC-dextran sulfate (MW 4kDa) exhibits significantly lower permeability across confluent BALB/c mouse brain microvascular endothelial cell monolayers than neutral 4kDa FITC-dextran, with greater permeability than 10kDa FITC-dextran sulfate[1].
References:
[1]. Sahagun G, et al. Permeability of neutral vs. anionic dextrans in cultured brain microvascular endothelium. The American journal of physiology. 1990 Jul;259(1 Pt 2):H162-6.
In Vitro, FITC-dextran sulfate (MW 4kDa) exhibits significantly lower permeability across confluent BALB/c mouse brain microvascular endothelial cell monolayers than neutral 4kDa FITC-dextran, with greater permeability than 10kDa FITC-dextran sulfate[1].
References:
[1]. Sahagun G, et al. Permeability of neutral vs. anionic dextrans in cultured brain microvascular endothelium. The American journal of physiology. 1990 Jul;259(1 Pt 2):H162-6.
















