FP-biotin is a potent organophosphorus toxicant, well-suited for searching for new biomarkers of organophosphorus toxicants exposure. FP-Biotin quantifies FAAH, ABHD6, and MAG-lipase activity. FP-biotin is used for studies with plasma because biotinylated peptides are readily purified by binding to immobilized avidin beads.
FP-biotin has good reactivity with human AChE and BChE despite its large biotin group. FP-biotin is suitable for the proposed task of identifying organophosphorus toxicants reactive proteins[1].