Bullatine A |
| Katalog-Nr.GC35567 |
Bullatine A, ein Diterpenoid-Alkaloid der Gattung Aconitum, besitzt antirheumatische, entzÜndungshemmende und antinozizeptive Wirkungen.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1354-84-3
Sample solution is provided at 25 µL, 10mM.
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Bullatine A (BLA), a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects. Bullatine A (BLA) is a potent P2X7 antagonist, inhibits ATP-induced cell death/apoptosis and P2X receptor-mediated inflammatory responses[1].Bullatine A attenuates pain hypersensitivity, regardless of the pain models employed[2].
[1]. Li J, et al. Bullatine A, a diterpenoid alkaloid of the genus Aconitum, could attenuate ATP-induced BV-2 microglia death/apoptosis via P2X receptor pathways. Brain Res Bull. 2013 Aug;97:81-5. [2]. Huang Q, et al. Bullatine A stimulates spinal microglial dynorphin A expression to produce anti-hypersensitivity in a variety of rat pain models. J Neuroinflammation. 2016 Aug 30;13(1):214.
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
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