CEF27, Epstein-Barr Virus BRLF-1 lytic 148-156 corresponding to amino acids 148-156 of the BRLF1 protein. BRLF1 is a transcriptional activator that binds directly to a GC-rich motif present in some Epstein-Barr virus (EBV) lytic gene promoters[1].
Expression of the EBV immediate-early (IE) protein BRLF1 induces the lytic form of viral replication in most EBV-positive cell lines[1].
[1]. Darr CD, et al. Epstein-Barr virus immediate-early protein BRLF1 induces the lytic form of viral replication through a mechanism involving phosphatidylinositol-3 kinase activation. J Virol. 2001 Jul;75(13):6135-42.