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Neocurdione

Katalog-Nr.GC36717 Copy One-Click Copy Product Info

Neocurdion ist ein hepatoprotektives Sesquiterpen, das aus dem Rhizom von Curcuma zedoaria isoliert wird.

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Neocurdione Chemische Struktur

Cas No.: 108944-67-8

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Sample solution is provided at 25 µL, 10mM.



Description of Neocurdione

Neocurdione is a hepatoprotective sesquiterpene isolated from Curcuma zedoaria rhizome. Neocurdione exerts potent effect on D-galactosamine- (D-Gain) and lipopolysaccharide- (LPS) induced acute liver injury in mice[1].

[1]. Carvalho FR, et al. Journal of Venomous Animals and Toxins including Tropical Diseases.On-line version ISSN 1678-9199 [2]. Omer Abdalla Ahmed Hamdi,et al. Neuroprotective and Antioxidant Constituents from Curcuma zedoaria Rhizomes. Records of Natural Products . 2015, Vol. 9 Issue 3, p349-355. 8p.

Chemical Properties of Neocurdione

Cas No. 108944-67-8 SDF
Canonical SMILES O=C1C[C@H](C(C)C)C(C/C(C)=C/CC[C@@H]1C)=O
Formula C15H24O2 M.Wt 236.35
Löslichkeit Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Neocurdione

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 4.231 mL 21.1551 mL 42.3101 mL
5 mM 846.2 μL 4.231 mL 8.462 mL
10 mM 423.1 μL 2.1155 mL 4.231 mL
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In vivo Formulation Calculator (Clear solution) of Neocurdione

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Review for Neocurdione

Average Rating: 5 ★★★★★ (Based on Reviews and 13 reference(s) in Google Scholar.)

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