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Monomethyl Itaconate (Synonyms: β-Methyl itaconate)

Katalog-Nr.GD16988 Copy One-Click Copy Product Info

Monomethyl itaconate (β-Methyl itaconate) is a monomethyl ester derivative ofItaconic acid.

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Monomethyl Itaconate Chemische Struktur

Cas No.: 7338-27-4

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Sample solution is provided at 25 µL, 10mM.



Description of Monomethyl Itaconate

Monomethyl itaconate (β-Methyl itaconate) is a monomethyl ester derivative ofItaconic acid. Monomethyl itaconate can copolymerize with PEGMA to form pH-sensitive hydrogels[1].

References:
[1].Teijón C, et al. Swelling properties of copolymeric hydrogels of poly(ethylene glycol) monomethacrylate and monoesters of itaconic acid for use in drug delivery. J Biomed Mater Res B Appl Biomater. 2009 Nov;91(2):716-726.

Chemical Properties of Monomethyl Itaconate

Cas No. 7338-27-4 SDF
Überlieferungen β-Methyl itaconate
Formula C6H8O4 M.Wt 144.13
Löslichkeit DMSO : 100 mg/mL(693.82 mM; Need ultrasonic) Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Monomethyl Itaconate

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 6.9382 mL 34.6909 mL 69.3818 mL
5 mM 1.3876 mL 6.9382 mL 13.8764 mL
10 mM 693.8 μL 3.4691 mL 6.9382 mL
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In vivo Formulation Calculator (Clear solution) of Monomethyl Itaconate

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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