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GDC-6036

Katalog-Nr.GC64510

GDC-6036 (Verbindung 17a) ist ein potenter K-Ras G12C-Inhibitor mit einem IC50 von < 0,01 μM. GDC-6036 hat eine EC50 von 2 nM in K-Ras G12C-Alkylierungs-HCC1171-Zellen.

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GDC-6036 Chemische Struktur

Cas No.: 2417987-45-0

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

GDC-6036 (compound 17a) is a potent K-Ras G12C inhibitor with an IC50 of <0.01 μM. GDC-6036 has an EC50 of 2 nM in K-Ras G12C-alkylation HCC1171 cells[1].

[1]. Sushant Malhotra, et al. Fused ring compounds. WO2020097537A2.

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