Manghaslin is a flavonoid glycoside with anti-inflammatory activities. Manghaslin shows inhibitory activity against AChE with an IC50 of 94.92 碌M.
Manghaslin reduces the release of NO in LPS-stimulated macrophages. Manghaslin also decreases the levels of TNF-伪 and Neopterin[1].
[1]. Hasan K谋rm谋z谋bekmez, et al. Phenolic compounds from the aerial parts of Clematis viticella L. and their in vitro anti-inflammatory activities. Nat Prod Res. 2019 Sep;33(17):2541-2544.
[2]. Daniil N Olennikov, et al. Isorhamnetin and Quercetin Derivatives as Anti-Acetylcholinesterase Principles of Marigold (Calendula officinalis) Flowers and Preparations. Int J Mol Sci. 2017 Aug 2;18(8):1685.