Die Produkte sind ausschließlich für Forschungszwecke bestimmt. Nicht zur Anwendung am Menschen. Wir verkaufen nicht an Patienten.
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 5mg | $84.00 | In Stock | 1 | |
| 10mg | $132.00 | In Stock | 1 | |
| 25mg | $262.00 | In Stock | 1 | |
| 50mg | $420.00 | In Stock | 1 |
DBCO-Palmitic is a functionalized fatty acid derivative formed by chemically coupling DBCO and palmitic acid. DBCO-Palmitic can be used in the azide-alkyne cycloaddition (SPAAC) reaction[1].
References:
[1] Cho J, Lim SI, Yang BS, Hahn YS, Kwon I. Generation of therapeutic protein variants with the human serum albumin binding capacity via site-specific fatty acid conjugation. Sci Rep. 2017;7(1):18041.
Protein-palmitic acid coupling via SPAAC[1]
This plan is based on literature, please modify it to meet your specific needs.
1. DBCO-Palmitic was mixed with azide-labeled protein at a ratio of 2:1 in a 20mM sodium phosphate buffer containing 0.2M sodium chloride and 1% dichloroacetic acid, and incubated at room temperature for 2 hours to generate a protein-palmitate conjugate.
2. Unreacted DBCO-Palmitic was removed using a PD-10 deionization column. The resulting protein-palmitate conjugate was stored at 4°C.
References:
[1] Cho J, Lim SI, Yang BS, Hahn YS, Kwon I. Generation of therapeutic protein variants with the human serum albumin binding capacity via site-specific fatty acid conjugation. Sci Rep. 2017;7(1):18041.