2',3'-Dideoxycytidine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. This ddCTP analog also contains a 1-Thiotriphosphate which results in a nuclease resistant phosphorothioate linkage. The inability of polymerases to extend from a dideoxy nucleotide causes chain termination and is useful in antiviral research and in a variety of biotechnology applications.
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Produktdokumente (Product Documents)
Purity:>90.00%Appearance:A solid
Chemische Eigenschaften (Chemical Properties)
Reinheit
>90.00%
Extinktionskoeffizient
9,100 Lmol-1cm-1 at 271 nm
Formel
C9H16N3O11P3S (free acid)
M.Wt
467.20 g/mole (free acid)
Salzform
Li+
Konzentration
100 mM
Puffer
H2O
Lagerung
-20°C or below
Synonyme
Alpha Thiol ddCTP, 1-Thio-ddCTP
Rückgrat
5'-O-(1-Thiotriphosphate)
Basenanalogon
Cytidine
Zuckertyp
2'-3'-Dideoxy
Nukleotidkategorie
Phosphate Modified
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