H-Hyp-OH (Synonyms: (S)-(-)-trans-4-Hydroxyproline, 4(R)-Hydroxy-2(S)-pyrrolidinecarboxylic acid, NSC 46704) |
| Katalog-Nr.GA11341 |
A chiral building block
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 51-35-4
Sample solution is provided at 25 µL, 10mM.
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L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.
L-Hydroxyproline (Trans-4-hydroxy-L-proline;Trans-Hyp) has been widely used in medicine, biochemistry, food, cosmetic and other aspects of industry. Additionally, L-Hydroxyproline has also been found in the composition of some secondary metabolites such as actinomycins and echinocandins. L-Hydroxyproline is manufactured industrially most by acid hydrolysis of mammalian collagen because of its rich amount in the collagen[1].
References:
[1]. Yi Y, et al. Biosynthesis of trans-4-hydroxyproline by recombinant strains of Corynebacterium glutamicum and Escherichia coli. BMC Biotechnol. 2014 May 19;14:44.
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