H-Phe(2-Cl)-OH, a phenylalanine derivative, is an intermediate used in the synthesis of amino acid derivatives[1]. H-Phe(2-Cl)-OH can be used as a model compound to study the polarization effect of hydrogen-bond complexes formed by phenol with water and chloride ions[2].
References:[1] Luckose F, Pandey M C, Radhakrishna K. Effects of amino acid derivativeson physical, mental, and physiological activities[J]. Critical reviews in food science and nutrition, 2015, 55(13): 1793-1807.
[2] Jorgensen W L, Jensen K P, Alexandrova A N. Polarization effects for hydrogen-bonded complexes of substituted phenols with water and chloride ion[J]. Journal of chemical theory and computation, 2007, 3(6): 1987.