HOAt |
| Katalog-Nr.GA10098 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 39968-33-7
Sample solution is provided at 25 µL, 10mM.
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A coupling activator for racemization-free coupling in peptide synthesis; An additive for peptide segment coupling in in reducing the extent of configurational loss at the reactive carboxylic acid residue. Carpino L A etc. works demonstrated that the DIC/HOAt system is more effective in preserving configuration for peptide segment coupling than the analogous DIC/HOBt system
in DMF and DCM. [1]
Reference:
[1].Carpino L A, El-Faham A. The diisopropylcarbodiimide/1-hydroxy-7-azabenzotriazole system: segment coupling and stepwise peptide assembly[J]. Tetrahedron, 1999, 55(22): 6813-6830.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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