HC-5404 is a novel, potent and highly selective PERK (Protein kinase RNA-like Endoplasmic Reticulum Kinase) inhibitor, blocking the activation of the PERK pathway, which in turn inhibits the endoplasmic reticulum stress response signaling pathway, thereby exerting anti-tumor effects, and can be used to treat advanced solid tumors and renal cell Cancer.
HC-5404
Catalog No.: GC27954Purity:>99.00%Synonyms: HC5404
HC-5404 is a novel, potent and highly selective PERK (Protein kinase RNA-like Endoplasmic Reticulum Kinase) inhibitor, blocking the activation of the PERK pathway, which in turn inhibits the endoplasmic reticulum stress response signaling pathway, thereby exerting anti-tumor effects, and can be used to treat advanced solid tumors and renal cell Cancer.
Die Produkte sind ausschließlich für Forschungszwecke bestimmt. Nicht zur Anwendung am Menschen. Wir verkaufen nicht an Patienten.
Cas No.: 2247396-91-2
1mgIn Stock
$113.00
1
5mgIn Stock
$282.00
1
10mgIn Stock
$410.00
1
25mgIn Stock
$626.00
1
50mgIn Stock
$861.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 1mg | $113.00 | In Stock | 1 | |
| 5mg | $282.00 | In Stock | 1 | |
| 10mg | $410.00 | In Stock | 1 | |
| 25mg | $626.00 | In Stock | 1 | |
| 50mg | $861.00 | In Stock | 1 |
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Zitate (Citations)
Für dieses Produkt sind derzeit keine Zitate verfügbar. Nachfolgend finden Sie ausgewählte Publikationen, die GlpBio-Produkte zitieren.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Beschreibung (Description)
Produktdokumente (Product Documents)
Purity:>99.00%Appearance:A solid
Chemische Eigenschaften (Chemical Properties)
CAS-Nr.
2247396-91-2
Synonyme
HC5404
Chemischer Name
CC1=C(C=2C=C(C(NC(C)C)=O)C(N)=NC2)C=CC(NC([C@H](O)C3=CC(F)=CC(F)=C3)=O)=C1
Summenformel
C24H24F2N4O3
Molekulargewicht
454.47
Lagerung
Powder: -20°C for 3 years | In solvent: -80°C for 1 year ,Keep away from moisture,Keep away from direct sunlight
Versandbedingungen
Evaluierungsmuster werden mit Kühlakkus versandt. Andere verfügbare Größen werden bei Raumtemperatur oder auf Anfrage mit Kühlakkus versandt.
Rechner (Calculators)Molarität / Verdünnung / Molekulargewicht / Einheitenumrechnung / In-vivo-Formulierung / Löslichkeit
g/mol
Reviews
Review for HC-5404
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