Hecameg |
Katalog-Nr.GB58765
One-Click Copy Product Info
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Hecameg is a type of alkyl polyglycoside surfactant with an amphiphilic structure, which can reduce the intermolecular contacts that lead to aggregation.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 115457-83-5
Sample solution is provided at 25 µL, 10mM.
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Hecameg is a type of alkyl polyglycoside surfactant with an amphiphilic structure, which can reduce the intermolecular contacts that lead to aggregation[1]. Hecameg has a relatively high critical micelle concentration (16.5mM), which is almost unaffected by changes in pH or ionic strength, and is suitable for the reconstitution process that requires the removal of detergents through dialysis[2]. Hecameg is an effective lipid solubilizer, which can cause the leakage of the contents within the vesicles [2]. Hecameg has been widely used to extract bacterial rhodopsin from the purple membrane of the Halobacterium halobium, and the extraction form remains unmodified[3]. Hecameg is used to solubilize spiralin protein from the Spiroplasma melliferum membrane, without detectable loss of antigenic properties[3].
References:
[1] Hierrezuelo J M, Nieto-Ortega B, Ruiz C C. Assessing the interaction of Hecameg® with Bovine Serum Albumin and its effect on protein conformation: A spectroscopic study[J]. Journal of luminescence, 2014, 147: 15-22.
[2] Ruiz M B, Prado A, Goñi F M, et al. An assessment of the biochemical applications of the non-ionic surfactant Hecameg[J]. Biochimica et Biophysica Acta (BBA)-Biomembranes, 1994, 1193(2): 301-306.
[3] Plusquellec D, Chevalier G, Talibart R, et al. Synthesis and characterization of 6-O-(N-heptylcarbamoyl)-methyl-α-D-glucopyranoside, a new surfactant for membrane studies[J]. Analytical biochemistry, 1989, 179(1): 145-153.
| Cas No. | 115457-83-5 | SDF | |
| Formula | C15H29NO7 | M.Wt | 335.39 |
| Löslichkeit | Storage | Store at 2-8°C | |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 2.9816 mL | 14.908 mL | 29.816 mL |
| 5 mM | 596.3 μL | 2.9816 mL | 5.9632 mL |
| 10 mM | 298.2 μL | 1.4908 mL | 2.9816 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)