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HOR1-C59

Katalog-Nr.GC81727 Copy One-Click Copy Product Info

HOR1-C59 is a highly selective Or5v1/Olfr110 agonist with an EC 50 of 7.12 nM.

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HOR1-C59 Chemische Struktur

Cas No.: 189574-20-7

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10mM (in 1mL DMSO)
116,00 $
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5mg
105,00 $
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10mg
164,00 $
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25mg
328,00 $
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Sample solution is provided at 25 µL, 10mM.



Description of HOR1-C59

HOR1-C59 is a highly selective Or5v1/Olfr110 agonist with an EC 50 of 7.12 nM. HOR1-C59 can improve glucose homeostasis, alleviate obesity and insulin resistance. HOR1-C59 is applicable for obesity-related research [1].

In Vivo, HOR1-C59 (50 ng/g; i.p.; daily; 8 weeks) improves glucose metabolism and reduces obesity in HFD-fed wild-type mice (effects absent in Olfr110−/− mice)[1].

References:
[1]. Ge XY, et al. Identification of Or5v1/Olfr110 as an oxylipin receptor and anti-obesity target. Cell. Published online January 21, 2026.

Chemical Properties of HOR1-C59

Cas No. 189574-20-7 SDF
Formula C21H24N2O4 M.Wt 368.43
Löslichkeit DMSO: 100 mg/mL (271.42 mM; Need ultrasonic) Storage Store at -20°C
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of HOR1-C59

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1 mg 5 mg 10 mg
1 mM 2.7142 mL 13.5711 mL 27.1422 mL
5 mM 542.8 μL 2.7142 mL 5.4284 mL
10 mM 271.4 μL 1.3571 mL 2.7142 mL
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In vivo Formulation Calculator (Clear solution) of HOR1-C59

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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