JWH 213 is a naphthoylindole-class synthetic cannabinoid (CB) which strongly binds both the central CB1 and peripheral CB2 receptor (Ki = 1.5 and 0.42 nM, respectively). [1] The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.
Reference:
[1]. Huffman, J.W., Zengin, G., Wu, M.J., et al. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: Steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists. Bioorg. Med. Chem. 13, 89-112 (2005).