Sphingolipids
Products Related to Sphingolipids(340)
- GC44898SLC5111312 (hydrochloride)CAS: 1870811-01-0Purity: >98.00%
SLC5111312 is a dual inhibitor of sphingosine kinase 1 (SPHK1) and SPHK2 (Kis = 0.73 and 0.9 μM, respectively, using human recombinant kinases).
- GC44901SLM6031434CAS: 1897379-33-7Purity: >98.00%
SLM6031434 is a selective inhibitor of sphingosine kinase 2 (SPHK2; Kis = 0.4 and >20 μM for mouse recombinant SPHK2 and SPHK1, respectively).
- GC44902SLP7111228 (hydrochloride)CAS: 1449768-48-2Purity: >95.00%
SLP7111228 is a potent and selective inhibitor of sphingosine kinase (SPHK) 1 with Ki values of 0.048 and >10 μM for SPHK1 and 2, respectively.
- GC44924Sphinganine (d17:0)CAS: 32164-02-6Purity: >95.00%
Sphinganine is a synthetic bioactive sphingolipid that inhibits the growth of C.
- GC44925Sphinganine (d20:0)CAS: 24006-62-0Purity: >98.00%
Sphinganine (d20:0) is a natural isomer of dihydro-D-erythro-sphinganine (sphinganine (d18:0);
- GC44926Sphinganine-1-phosphate (d17:0)CAS: 474923-29-0Purity: >95.00%
Sphinganine-1-phosphate (d17:0) is a sphingolipid analog of sphinganine-1-phosphate (d18:0) and sphingosine-1-phosphate (d18:1) that has a 17-carbon base.
- GC44927Sphinganine-1-phosphate (d18:0)CAS: 19794-97-9Purity: >95.00%
Sphinganin-1-phosphat (d18:0) (D-erythro-Dihydrosphingosin-1-phosphat) ist ein polarer Sphingolipid-Metabolit, der Zellmigration, -differenzierung, -Überleben und komplexe physiologische Prozesse reguliert.
- GC44929Sphingosine (d12:1)CAS: 128427-86-1Purity: >95.00%
Sphingosin (d12:1) ist ein kurzkettiges Sphingosin-Homolog.
- GC44930Sphingosine (d14:1)CAS: 24558-60-9Purity: >98.00%
Sphingosin (d14:1) (Tetradecasphing-4-enin), ein Sphingolipid, ist ein potenter Proteinkinase C (PKC)-Inhibitor. Sphingosin (d14:1) verhindert seine Wechselwirkung mit sn-1,2-Diacylglycerol (DAG)/Phorbol-Estern.
- GC44931Sphingosine (d15:1)CAS: 86555-28-4Purity: >98.00%
Sphingosine is an amino alcohol most commonly characterized by an 18-carbon unsaturated hydrocarbon chain (Sphingosine (d18:1)
- GC44932Sphingosine (d17:1)CAS: 6918-48-5Purity: >98.00%
Sphingosin (d17:1) ist ein 17-Kohlenstoff-Sphingosin, das in der menschlichen Haut vorkommt.
- GC44933Sphingosine (d18:1) AlkyneCAS: 954096-91-4Purity: >95.00%
Sphingosine alkyne is an ω-alkyne form of sphingosine (d18:1).
- GC44934Sphingosine-1-phosphate (d16:1)CAS: 709026-60-8Purity: >95.00%
C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO cells.
- GC44935Sphingosine-1-phosphate (d17:1)CAS: 474923-27-8Purity: >95.00%
Sphingosine-1-phosphate (S1P) (d17:1) is a synthetic sphingolipid that has been used as an internal standard for the quantification of sphingosine-1-phosphate (d18:1) in plasma and tissue samples.
- GC45154W140 (trifluoroacetate salt)CAS: 909725-64-0Purity: >95.00%
Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.
- GC45155W146 (trifluoroacetate salt)CAS: 909725-62-8Purity: >95.00%
W146 (Trifluoracetatsalz) ist ein selektiver Antagonist des Sphingosin-1-Phosphat-Rezeptors 1 (S1PR1) mit einem EC50-Wert von 398 nM.
- GC45175YVAD-CHO (trifluoroacetate salt)Purity: >95.00%
YVAD-CHO is an inhibitor of caspase-1/interleukin-1β converting enzyme (ICE) and a non-acetylated form of Ac-YVAD-CHO.
- GC45206α-GalCer analog 8CAS: 922727-14-8Purity: >95.00%
α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide.
- GC45250(-)-L-threo-PDMP (hydrochloride)CAS: 161491-04-9Purity: >98.00%
(-)-L-threo-PDMP is an enhancer of ganglioside biosynthesis.
- GC45263(+)-D-threo-PDMP (hydrochloride)CAS: 139889-62-6Purity: >98.00%
(+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP.
- GC45661C16 Sphingomyelin-d9 (d18:1/16:0-d9)CAS: 2415226-88-7Purity: >99.00%
A neuropeptide with diverse biological activities
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC44898 | SLC5111312 (hydrochloride) | 1870811-01-0 | >98.00% | |
SLC5111312 is a dual inhibitor of sphingosine kinase 1 (SPHK1) and SPHK2 (Kis = 0.73 and 0.9 μM, respectively, using human recombinant kinases). | ||||
| GC44901 | SLM6031434 | 1897379-33-7 | >98.00% | |
SLM6031434 is a selective inhibitor of sphingosine kinase 2 (SPHK2; Kis = 0.4 and >20 μM for mouse recombinant SPHK2 and SPHK1, respectively). | ||||
| GC44902 | SLP7111228 (hydrochloride) | 1449768-48-2 | >95.00% | |
SLP7111228 is a potent and selective inhibitor of sphingosine kinase (SPHK) 1 with Ki values of 0.048 and >10 μM for SPHK1 and 2, respectively. | ||||
| GC44924 | Sphinganine (d17:0) | 32164-02-6 | >95.00% | |
Sphinganine is a synthetic bioactive sphingolipid that inhibits the growth of C. | ||||
| GC44925 | Sphinganine (d20:0) | 24006-62-0 | >98.00% | |
Sphinganine (d20:0) is a natural isomer of dihydro-D-erythro-sphinganine (sphinganine (d18:0); | ||||
| GC44926 | Sphinganine-1-phosphate (d17:0) | 474923-29-0 | >95.00% | |
Sphinganine-1-phosphate (d17:0) is a sphingolipid analog of sphinganine-1-phosphate (d18:0) and sphingosine-1-phosphate (d18:1) that has a 17-carbon base. | ||||
| GC44927 | Sphinganine-1-phosphate (d18:0) | 19794-97-9 | >95.00% | |
Sphinganin-1-phosphat (d18:0) (D-erythro-Dihydrosphingosin-1-phosphat) ist ein polarer Sphingolipid-Metabolit, der Zellmigration, -differenzierung, -Überleben und komplexe physiologische Prozesse reguliert. | ||||
| GC44929 | Sphingosine (d12:1) | 128427-86-1 | >95.00% | |
Sphingosin (d12:1) ist ein kurzkettiges Sphingosin-Homolog. | ||||
| GC44930 | Sphingosine (d14:1) | 24558-60-9 | >98.00% | |
Sphingosin (d14:1) (Tetradecasphing-4-enin), ein Sphingolipid, ist ein potenter Proteinkinase C (PKC)-Inhibitor. Sphingosin (d14:1) verhindert seine Wechselwirkung mit sn-1,2-Diacylglycerol (DAG)/Phorbol-Estern. | ||||
| GC44931 | Sphingosine (d15:1) | 86555-28-4 | >98.00% | |
Sphingosine is an amino alcohol most commonly characterized by an 18-carbon unsaturated hydrocarbon chain (Sphingosine (d18:1) | ||||
| GC44932 | Sphingosine (d17:1) | 6918-48-5 | >98.00% | |
Sphingosin (d17:1) ist ein 17-Kohlenstoff-Sphingosin, das in der menschlichen Haut vorkommt. | ||||
| GC44933 | Sphingosine (d18:1) Alkyne | 954096-91-4 | >95.00% | |
Sphingosine alkyne is an ω-alkyne form of sphingosine (d18:1). | ||||
| GC44934 | Sphingosine-1-phosphate (d16:1) | 709026-60-8 | >95.00% | |
C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO cells. | ||||
| GC44935 | Sphingosine-1-phosphate (d17:1) | 474923-27-8 | >95.00% | |
Sphingosine-1-phosphate (S1P) (d17:1) is a synthetic sphingolipid that has been used as an internal standard for the quantification of sphingosine-1-phosphate (d18:1) in plasma and tissue samples. | ||||
| GC45154 | W140 (trifluoroacetate salt) | 909725-64-0 | >95.00% | |
Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. | ||||
| GC45155 | W146 (trifluoroacetate salt) | 909725-62-8 | >95.00% | |
W146 (Trifluoracetatsalz) ist ein selektiver Antagonist des Sphingosin-1-Phosphat-Rezeptors 1 (S1PR1) mit einem EC50-Wert von 398 nM. | ||||
| GC45175 | YVAD-CHO (trifluoroacetate salt) | - | >95.00% | |
YVAD-CHO is an inhibitor of caspase-1/interleukin-1β converting enzyme (ICE) and a non-acetylated form of Ac-YVAD-CHO. | ||||
| GC45206 | α-GalCer analog 8 | 922727-14-8 | >95.00% | |
α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. | ||||
| GC45250 | (-)-L-threo-PDMP (hydrochloride) | 161491-04-9 | >98.00% | |
(-)-L-threo-PDMP is an enhancer of ganglioside biosynthesis. | ||||
| GC45263 | (+)-D-threo-PDMP (hydrochloride) | 139889-62-6 | >98.00% | |
(+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP. | ||||
| GC45616 | C6 Urea Ceramide | 486991-52-0 | >95.00% | |
An inhibitor of neutral ceramidase | ||||
| GC45638 | Sphingosine (d18:1(14Z)) | - | >95.00% | |
An atypical sphingolipid | ||||
| GC45661 | C16 Sphingomyelin-d9 (d18:1/16:0-d9) | 2415226-88-7 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC45663 | C22 1-Deoxyceramide (m18:1(14Z)/22:0) | - | >95.00% | |
A long-chain atypical ceramide | ||||