N-Methylnorsalsolinol is an endogenous MPTP -like compound. N-Methylnorsalsolinol shows neurotoxicity in vitro. N-Methylnorsalsolinol can be used for the study of Parkinson’s disease [1].
In Vivo, N-Methylnorsalsolinol is identified in the rat brain dialysate after epinine perfusion using gas chromatography-selected-ion monitoring mass spectrometry (GC-SIM-MS)[1].
References:
[1]. Kajita M, et al. Endogenous synthesis of N-methylnorsalsolinol in rat brain during in vivo microdialysis with epinine. J Chromatogr B Biomed Appl. 1994 Apr 1;654(2):263-9.
In Vivo, N-Methylnorsalsolinol is identified in the rat brain dialysate after epinine perfusion using gas chromatography-selected-ion monitoring mass spectrometry (GC-SIM-MS)[1].
References:
[1]. Kajita M, et al. Endogenous synthesis of N-methylnorsalsolinol in rat brain during in vivo microdialysis with epinine. J Chromatogr B Biomed Appl. 1994 Apr 1;654(2):263-9.