PA-JF549-Halo ligand is a covalently linked conjugate comprising the photoactivatable fluorescent dye PA-JF549 and a ligand for the HaloTag protein. PA-JF549-Halo ligand exhibts inherent structural properties and predispose it to localize within mitochondria. PA-JF549-Halo ligand combines the exceptional brightness, photostability, and cell permeability of the JF549 dye with photoactivation capabilities and the high specificity characteristic of HaloTag protein labeling technology. PA-JF549-Halo ligand enables high-quality single-molecule imaging and super-resolution imaging of specific proteins within live cells [1].
References:
[1]. Grimm JB, et al. Bright photoactivatable fluorophores for single-molecule imaging. Nat Methods. 2016 Dec;13(12):985-988.
References:
[1]. Grimm JB, et al. Bright photoactivatable fluorophores for single-molecule imaging. Nat Methods. 2016 Dec;13(12):985-988.