Prostaglandins

1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether.

Prostaglandin B1 (PGB1) is a non-enzymatic dehydration product of PGE1 resulting from treatment with strong base.

Polmacoxib (CG100649) ist das erste oral wirksame nichtsteroidale Antirheumatikum (NSAID) seiner Klasse, das ein dualer Inhibitor von COX-2 (IC50 etwa 0,1 μg/ml) und Carboanhydrase ist. Polmacoxib hemmt kolorektale Adenome und Tumorwachstum in Mausmodellen.

Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen.

15-keto PGE1 is the inactive metabolite of PGE1 produced by 15-hydroxy PGDH.

A naturally occurring prostaglandin with antiviral/antitumor activity

Prostaglandin F2α methyl ester (PGF2α methyl ester) is an analog of PGF2α in which the C-1 carboxyl group has been esterified as the methyl ester.

15(S)-15-methyl PGF2α methyl ester is a derivative of 15(S)-15-methyl PGF2α with increased membrane permeability.

Prostaglandin H2 (PGH2) was first isolated from incubations of arachidonic acid with ovine seminal vesicle microsomes, and was described as a potent vasoconstrictor.

Prostaglandin G2 (PGG2) is the first intermediate in the COX pathway which is stable enough to be isolated and characterized.

6-keto prostaglandin F1α (6-keto PGF1α) is the inactive, non-enzymatic hydrolysis product of PGI2.

Prostaglandin B2 (PGB2) is a non-enzymatic dehydration product resulting from the treatment of PGE2 or PGA2 with strong base.

A major active metabolite of flurbiprofen

Tafluprost-Ethylamid ist ein Prostaglandin-Derivat.

A metabolite of meloxicam

11β-Prostaglandin E1 (11β-PGE1) is an epimerized form of PGE1 at the C-11 position.

11-deoxy Prostaglandin E1 (11-deoxy PGE1) is a synthetic analog of PGE1.

11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo.

Prostaglandin J2 (PGJ2) is formed from PGD2 by the elimination of the C-9 hydroxyl group, a process which is accelerated by the presence of albumin.

Microsomal Prostaglandin E2 Synthase-1 (mPGES-1), with cyclooxygenase-2 (COX-2), synthesizes PGE2, which is directly involved in signaling during inflammation, fever and pain.

Prostaglandin E2 is the major PG synthesized at sites of inflammation and plays an important role in different inflammatory diseases.

Prostaglandin E1 ethanolamide (PGE1-EA) is the ethanolamine-amide analog of PGE1.

17-trans PGE3 is an isomer of PGE3 which could theoretically result from the COX metabolism of dietary trans-fatty acids.

Prostaglandin E1 (PGE1) alcohol is a non-irritant bronchodilator, with relaxant activity on the human bronchial muscle in vitro, comparable to PGE1 at concentrations of 0.01 to 10.0 ug/ml.