Drug Metabolite
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
Products Related to Drug Metabolite(546)
- GC49399N-Desbutyl Dronedarone (hydrochloride)CAS: 197431-02-0Purity: >95.00%
Debutyldronedaron (SR35021)-Hydrochlorid, der Hauptmetabolit von Dronedaron, ist ein selektiver Inhibitor des SchilddrÜsenhormonrezeptors α1 (TRα1).
- GC49406ACT-373898CAS: 1433875-14-9Purity: >90.00%
ACT-373898 ist ein inaktiver CarbonsÄuremetabolit von Macitentan.
- GC49421Atorvastatin lactone-d5CAS: 125995-03-1Purity: >99.00%
An internal standard for the quantification of atorvastatin lactone
- GC49428O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipineCAS: 113994-45-9Purity: >95.00%
A major metabolite of amlodipine
- GC49480Salicylic Acid-d4CAS: 78646-17-0Purity: >98.00%
SalicylsÄure-d4 ist das mit Deuterium markierte 2-Carboxyphenol.
- GC494886-Methylmercaptopurine-d3CAS: 33312-93-5Purity: >99.00%
An internal standard for the quantification of 6-MMP
- GC49559Hydroxymethyl Tolperisone (hydrochloride)CAS: 352233-14-8Purity: >95.00%
A metabolite of tolperisone
- GC49565RoxatidineCAS: 78273-80-0Purity: >95.00%
Roxatidin ist ein aktiver Metabolit von Roxatidinacetathydrochlorid, ein Antagonist des Histamin-H2-Rezeptors.
- GC49583N-desmethyl Sertraline (hydrochloride)CAS: 675126-09-7Purity: >95.00%
A metabolite of sertraline
- GC49637O-desethyl DapagliflozinCAS: 864070-37-1Purity: >98.00%
An SGLT2 inhibitor and active metabolite of dapagliflozin
- GC49677Olmesartan-d6CAS: 1185144-74-4Purity: >99.00%
An internal standard for the quantification of olmesartan
- GC49686N-desmethyl Regorafenib N-oxideCAS: 835621-12-0Purity: >90.00%
An active metabolite of regorafenib
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC49399 | N-Desbutyl Dronedarone (hydrochloride) | 197431-02-0 | >95.00% | |
Debutyldronedaron (SR35021)-Hydrochlorid, der Hauptmetabolit von Dronedaron, ist ein selektiver Inhibitor des SchilddrÜsenhormonrezeptors α1 (TRα1). | ||||
| GC49403 | Benzarone | 1477-19-6 | >98.00% | |
Benzaron (Fragivix) ist ein starker Hemmer des menschlichen HarnsÄuretransporters 1 (hURAT1) mit einem IC50-Wert von 2,8 μM in der Eizelle. | ||||
| GC49406 | ACT-373898 | 1433875-14-9 | >90.00% | |
ACT-373898 ist ein inaktiver CarbonsÄuremetabolit von Macitentan. | ||||
| GC49409 | Desmethyl Ranolazine | 172430-45-4 | >95.00% | |
A metabolite of ranolazine | ||||
| GC49410 | CVT-2738 | 5294-61-1 | >98.00% | |
An active metabolite of ranolazine | ||||
| GC49421 | Atorvastatin lactone-d5 | 125995-03-1 | >99.00% | |
An internal standard for the quantification of atorvastatin lactone | ||||
| GC49428 | O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine | 113994-45-9 | >95.00% | |
A major metabolite of amlodipine | ||||
| GC49480 | Salicylic Acid-d4 | 78646-17-0 | >98.00% | |
SalicylsÄure-d4 ist das mit Deuterium markierte 2-Carboxyphenol. | ||||
| GC49488 | 6-Methylmercaptopurine-d3 | 33312-93-5 | >99.00% | |
An internal standard for the quantification of 6-MMP | ||||
| GC49501 | Nirvanol | 631-07-2 | >98.00% | |
An active metabolite of mephenytoin | ||||
| GC49511 | Nicorandil N-oxide | 107833-98-7 | >98.00% | |
A metabolite of nicorandil | ||||
| GC49538 | Lamotrigine N2-oxide | 136565-76-9 | >95.00% | |
A metabolite of lamotrigine | ||||
| GC49544 | 8-hydroxy Mirtazapine | 102335-57-9 | >95.00% | |
A metabolite of mirtazapine | ||||
| GC49559 | Hydroxymethyl Tolperisone (hydrochloride) | 352233-14-8 | >95.00% | |
A metabolite of tolperisone | ||||
| GC49565 | Roxatidine | 78273-80-0 | >95.00% | |
Roxatidin ist ein aktiver Metabolit von Roxatidinacetathydrochlorid, ein Antagonist des Histamin-H2-Rezeptors. | ||||
| GC49575 | 4-hydroxy Omeprazole sulfide | 103876-98-8 | >98.00% | |
A metabolite of omeprazole | ||||
| GC49583 | N-desmethyl Sertraline (hydrochloride) | 675126-09-7 | >95.00% | |
A metabolite of sertraline | ||||
| GC49627 | Rabeprazole sulfone | 117976-47-3 | >95.00% | |
A metabolite of rabeprazole | ||||
| GC49629 | 6β-hydroxy Prednisolone | 16355-29-6 | >95.00% | |
A metabolite of prednisolone | ||||
| GC49637 | O-desethyl Dapagliflozin | 864070-37-1 | >98.00% | |
An SGLT2 inhibitor and active metabolite of dapagliflozin | ||||
| GC49655 | 5-hydroxy Buspirone | 105496-33-1 | >95.00% | |
A metabolite of buspirone | ||||
| GC49676 | 6β-hydroxy Budesonide | - | >95.00% | |
A metabolite of budesonide | ||||
| GC49677 | Olmesartan-d6 | 1185144-74-4 | >99.00% | |
An internal standard for the quantification of olmesartan | ||||
| GC49686 | N-desmethyl Regorafenib N-oxide | 835621-12-0 | >90.00% | |
An active metabolite of regorafenib | ||||