Drug Metabolite
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
Ziele für Drug Metabolite
Produkte für Drug Metabolite
- Bestell-Nr. Artikelname Informationen
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GC45208
α-hydroxy Metoprolol
α-hydroxy Metoprolol is an active metabolite of the β1-adrenergic receptor blocker metoprolol.
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GC40480
α-Phenyl-α-(2-pyridyl)acetonitrile
NSC 16276, 2-Pyridylphenylacetonitrile
α-Phenyl-α-(2-pyridyl)thioacetamide, also known as antigastrin and SC-15396, is an inhibitor of gastric acid secretion. -
GC41661
(±)-4-hydroxy Propranolol β-D-Glucuronide
(±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol, which is a metabolite of propranolol.
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GC46284
(±)-Cotinine-d3
An internal standard for the quantification of cotinine
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GC41671
(±)-Equol 4'-sulfate (sodium salt)
R,S-Equol 4'-Sulfate
(±)-Equol 4'-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol.
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GC41315
(±)-Ketoprofen Glucuronide
rac-Ketoprofen Acyl-β-D-glucuronide, (R,S)-Ketoprofen Glucuronide
(±)-Ketoprofen glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) ketoprofen.
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GC49875
(±)-N-desmethyl Venlafaxine (hydrochloride)
Wy 45494
A minor active metabolite of venlafaxine -
GC45252
(-)-Sitagliptin Carbamoyl Glucuronide
(R)-Sitagliptin Carbamoyl Glucuronide
(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin. -
GC18622
(2'S)-Nicotine-1-oxide
Nicotine-N-oxide
(2'S)-Nicotine-1-oxide is a metabolite of nicotine . -
GC68509
(25R)-12α-Hydroxyspirost-4-en-3-one
(25R)-12α-Hydroxyspirost-4-en-3-one ist ein sekundäres Stoffwechselprodukt, das durch die Wirkung von Nocardia globerula auf Hecogenin entsteht.
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GC41694
(3S)-hydroxy Quinidine
(3S)-hydroxy Quinidine is an active quinidine metabolite.
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GC60399
(E)-10-Hydroxynortriptyline
10(E)-hydroxy Nortriptyline
(E)-10-Hydroxynortriptylin (E-10-OH-NT) ist ein Metabolit von Nortriptylin. -
GC91418
(E)-KPT-330
KTP-330; trans Selinexor
(E)-KPT-330 ist ein Metabolit des Exportin 1 (XPO1/CRM1) Inhibitors Selinexor.
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GC40286
(E,Z)-2-propyl-2-Pentenoic Acid
2-propyl-2-Pentenoate, 2-propylpenten-2-oic Acid, 2-ene-VPA
(E,Z)-2-propyl-2-Pentenoic acid is a bioactive metabolite of valproic acid that exhibits the same profile and potency of anticonvulsant activity in animal models as its parent compound without any observed teratogenicity and hepatotoxicity. -
GC49189
(E/Z)-4-hydroxy Tamoxifen-d5
Afimoxifene-d5, 4-OHT-d5
An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen -
GC62737
(R)-(-)-O-Desmethyl Venlafaxine D6
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GC41722
(R,S)-Carvedilol Glucuronide
(R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide.
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GC60410
(Rac)-3′-Hydroxy simvastatin
(Rac)-3′-Hydroxy Simvastatin ist ein Metabolit von Simvastatin.
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GC41736
(S)-Dibutyl 3-Hydroxybutyl Phosphate
(S)TBPOH
Dibutyl 3-hydroxybutyl phosphate is a compound produced from the metabolism of the organophosphorus solvent, tributyl phosphate (TBP). -
GC40145
(S)-Laudanosine
(+)-Laudanosine, L-Laudanosine, L-(+)-Laudanosine, NSC 35045
(S)-Laudanosine is the (S) enantiomer of laudanosine, a metabolite of the neuromuscular blocking agents atracurium and cisatracurium. -
GC49179
(S)-O-Desmethyl Naproxen
(S)-6-Desmethyl Naproxen
A metabolite of (S)-naproxen -
GC60419
(S)-O-Desmethyl Venlafaxine N-Oxide
(S)-O-Desmethyl-Venlafaxin-N-Oxid ist ein N-Oxid von (S)-O-Desmethyl-Venlafaxin.
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GC60427
(Z)-10-Hydroxynortriptyline
10(Z)-hydroxy Nortriptyline
(Z)-10-Hydroxynortriptylin ist ein Metabolit von Nortriptylin. -
GC67761
(Z)-10-Hydroxynortriptyline-d3
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GC18596
(±)-2-propyl-4-Pentenoic Acid
2-Allylpentanoic Acid, 4-ene VPA
(±)-2-Propyl-4-pentensÄure (4-en-VPA) ist ein wichtiger toxischer Metabolit von ValproinsÄure. -
GC41995
1'-hydroxy Midazolam
Ro 21-6347
Hauptmetabolit des Anästhetikums Midazolam.
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GC41837
1,3,7-Trimethyluric Acid
8-oxo Caffeine, NSC 11259
1,3,7-TrimethylursÄure ist der Metabolit von Koffein. Das metabolische VerhÄltnis von 1,3,7-TrimethylursÄure zu Koffein kann als Biomarker zur Beschreibung der VariabilitÄt der CYP3A-AktivitÄt in einer Kohorte ausgewertet werden. -
GC46387
1,3,7-Trimethyluric Acid-d9
TMU-d9, 8-oxo Caffeine-d9
An internal standard for the quantification of 1,3,7-trimethyluric acid -
GC49294
1-(4-Chlorobenzhydryl)piperazine
N-(p-Chlorobenzhydryl)-piperazine, Norchlorcyclizine, NSC 86164
An inactive metabolite of meclizine and chlorcyclizine -
GC49366
1-Salicylate Glucuronide
Salicyl Phenolic Glucuronide, Salicylic Acid Phenolic Glucuronide
A metabolite of salicylic acid and aspirin -
GC49820
10,11-dihydro-10,11-dihydroxy Carbamazepine
10,11-dihydro-10,11-dihydroxy CBZ, CBZ-diol, Dihydroxycarbazepine, Dihydroxycarbamazepine
A metabolite of carbamazepine and oxcarbazepine -
GC66057
10,11-Dihydrocarbamazepine
10,11-Dihydrocarbamazepin ist der aktive Metabolit von Oxcarbazepin. 10,11-Dihydrocarbamazepin ist ebenfalls ein Zwischenprodukt. Oxcarbazepin wird schnell und fast vollstÄndig in 10,11-Dihydrocarbazepin mit wahrscheinlicher antikonvulsiver Wirksamkeit umgewandelt.
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GC49118
10-hydroxy Warfarin
A metabolite of (R)-warfarin
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GC49759
13C17-Mycophenolic Acid
13C17-MPA
An internal standard for the quantification of mycophenolic acid -
GC19442
15-Acetyldeoxy Nivalenol
15-Acetyl Vomitoxin, 15-AcDON, Deoxynivalenol 15-acetate, DON 15-acetate
15-Acetyldeoxy-Nivalenol ist ein hochgiftiges Trichothecen, das in Getreide vorkommt, und ein Metabolit von Deoxynivalenol, der für HepG2-Zellen toxisch ist. -
GC41937
15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide
15ketoBimatoprost, 17phenyl trinor PGF2α ethyl amide
Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. -
GC41309
16α-hydroxy Prednisolone
16α-Hydroxy-Prednisolon ist ein stereoselektiver Metabolit des 22(R)-Epimers des Glukokortikoids Budesonid Über Cytochrom P450 3A (CYP3A)-Enzyme.
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GC41300
17β-hydroxy Exemestane
17β-hydroxy Exemestane is the primary active metabolite of exemestane.
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GC46471
17β-hydroxy Exemestane-d3
A neuropeptide with diverse biological activities
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GC71042
18β-Glycyrrhetyl-3-O-sulfate
18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetsäure 3-O-(Wasserstoffsulfat)) ist ein potenter Typ 2 11β-Hydroxysteroid Dehydrogenase (11β-HSD2)-Hemmer mit einem IC50 von 0,10 µM unter Verwendung von Rattennierenmikrosomen.
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GC49823
2′-C-β-Methylguanosine
An active nucleoside metabolite of BMS-986094
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GC46508
2',2'-Difluoro-2'-deoxyuridine
dFdU
An active metabolite of gemcitabine -
GC49159
2-(1-Piperazinyl)pyrimidine
PmP, 1-PP, 1-(2-Pyrimidyl)piperazine
An α2-AR antagonist and active metabolite of azapirones -
GC49330
2-(2-Aminoethyl)-3-(4-chlorophenyl)-3-hydroxyisoindol-1-one (hydrochloride)
A metabolite of mazindol
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GC52029
2-Aminoflubendazole
Hydrolyzed Flubendazole
2-Aminoflubendazol ist der Metabolit von Benzimidazolen. -
GC46539
2-Chloroadenine
6-amino-2-chloropurine, 2-chloro-6-aminopurine, NSC 7362
A heterocyclic building block -
GC40675
2-deoxy-Artemisinin
2-deoxy-Artemisinin is an inactive metabolite of the antimalarial agent artemisinin.
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GC35090
2-Hydroxy atorvastatin calcium salt
o-hydroxy Atorvastatin, ortho-hydroxy Atorvastatin, BMS 243887-01, PD 152873
2-Hydroxy-Atorvastatin-Calciumsalz ist ein Hydroxy-Metabolit von Atorvastatin-Calciumsalz. -
GC60474
2-Hydroxy atorvastatin lactone
2-Hydroxy-Atorvastatin-Lacton ist ein Metabolit von Atorvastatin.
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GC64336
2-Hydroxyemodin
2-Hydroxyemodin ist ein aktiver Metabolit von Emodin in den Lebermikrosomen.
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GC62777
2-Methoxy-4-vinylphenol
2-Methoxy-4-vinylphenol (2M4VP), ein natÜrlicher Keimhemmer, Übt starke entzÜndungshemmende Wirkungen aus.
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GC70763
2-NP-AMOZ
2-NP-AMOZ ist ein 2-Nitrophenyl-Derivat von AMOZ (einem Metaboliten des Antibiotikums Furaltadon), das zum Nachweis proteinbundener AMOZ verwendet werden kann.
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GC42189
2-oxo Clopidogrel
2-oxo Clopidogrel is an intermediary metabolite of clopidogrel.
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GC40968
21-hydroxy Eplerenone
21-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone.
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GC35079
24, 25-Dihydroxy VD2
24, 25-Dihydroxy VD2 ist ein hydroxylierter Metabolit von Vitamin D2; ein synthetisches Analogon von Vitamin D.
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GC49365
25-Desacetyl Rifampicin
Desacetylrifampicin
A major active metabolite of rifampicin -
GC62033
3α-Hydroxy pravastatin sodium
3α-Isopravastatin, R-416
3α-Hydroxy Pravastatin-Natrium ist der Hauptmetabolit von Pravastatin. -
GC41480
3'-hydroxy Lidocaine
m-hydroxy Lidocaine, meta-hydroxy Lidocaine
3'-hydroxy Lidocaine is an active metabolite of lidocaine formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4. -
GC39611
3'-Hydroxy Repaglinide
3'-Hydroxy-Repaglinid ist ein CYP2C8-Hauptmetabolit von Repaglinid.
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GC60500
3'-Hydroxy Repaglinide D5
3'-Hydroxy-Repaglinid D5 ist das mit Deuterium markierte 3'-Hydroxy-Repaglinid.
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GC68082
3,4,5-Trimethoxyphenylacetic acid
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GC39841
3,4-Dehydro Cilostazol
OPC 13015
3,4-Dehydro Cilostazol (OPC-13015) ist ein aktiver Metabolit von Cilostazol. -
GC52324
3-(3-Hydroxyphenyl)propionic Acid sulfate
3-HPPA sulfate
A metabolite of certain phenols and glycosides -
GC42198
3-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt)
γ-Hydroxybaclofen
An inactive metabolite of baclofen -
GC46583
3-Amino-2,6-Piperidinedione
α-Aminoglutarimide, 3-Aminoglutarimide, Glutamimide
An active metabolite of (±)-thalidomide -
GC67902
3-Amino-2-oxazolidinone-d4
AOZ-d4
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GC42274
3-hydroxy Darifenacin
UK 148993
3-hydroxy Darifenacin is a metabolite of darifenacin. -
GC42275
3-hydroxy Desloratidine
SCH 45581
3-hydroxy Desloratidine is a major metabolite of desloratadine , a tricyclic antagonist of the histamine H1 receptor. -
GC41565
3-hydroxy Medetomidine
3-OH Medetomidine, Medetomidine metabolite MIII
3-hydroxy Medetomidine is a metabolite of the α2-adrenergic receptor agonist medetomidine. -
GC90789
3-hydroxy Xylazine
Ein Stoffwechselprodukt von Xylazin.
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GC48457
3-keto Fusidic Acid
3-keto FA, 3-Oxofusidic Acid
An active metabolite of fusidic acid -
GC33738
3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride)
3-Methoxy-4-hydroxyphenethylamine, 3-Methoxy-p-hydroxyphenethylamine, 3-O-methyl Dopamine
3-Methoxytyraminhydrochlorid (3-O-Methyldopaminhydrochlorid) ist ein inaktiver Metabolit von Dopamin, der den Spurenamin-assoziierten Rezeptor 1 (TAAR1) aktivieren kann. -
GC68324
3-Methoxytyramine-d4 hydrochloride
3-O-methyl Dopamine-d4 hydrochloride
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GC49869
3-Methoxytyrosine
DL-3-O-Methyldopa, NSC 122476, 3-methoxy-DL-Tyrosine
An active metabolite of L-DOPA -
GC42307
3-O-methyl-L-DOPA (hydrate)
3-O-methyl-3,4-Dihydroxyphenylalanine, 3-methoxy DOPA, 3-OMD
3-O-methyl-L-DOPA is a metabolite of L-DOPA, produced by the activity of catechol O-methyltransferase. -
GC49367
4’-hydroxy Atomoxetine Glucuronide (hydrate)
A metabolite of atomoxetine
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GC49252
4’-hydroxy Trazodone
A metabolite of trazodone
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GC18527
4'-hydroxy Flurbiprofen
A major active metabolite of flurbiprofen
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GC49752
4,5-Desisopropylidene Topiramate
4,5-Desisopropylidene TPM
An inactive metabolite of topiramate -
GC49337
4-Acetamidobenzenesulfonamide
APAS, N-Acetyl p-Aminobenzene Sulfonamide, N4-Acetyl Sulfanilamide, N-Acetylsulfanilamide, NSC 217, NSC 406839
A metabolite of asulam and sulfanilamide -
GC42370
4-desmethoxy Omeprazole
4-desmethoxy OMEP, 4-desmethoxy OMP, 4-desmethoxy OMZ, Esomeprazol Magnesium Impurity B, Omeprazole EP Impurity B
4-Desmethoxy Omeprazol ist der aktive Metabolit von Omeprazol. -
GC18194
4-Epidoxycycline
4-ED
4-Epidoxycycline is the 4-epimer hepatic metabolite of the antibiotic doxycycline . -
GC42401
4-hydroperoxy Cyclophosphamide
4-OOH-CY
Ein aktiviertes Analogon von Cyclophosphamid.
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GC42402
4-hydroxy (S)-Duloxetine β-D-Glucuronide (sodium salt)
LY550408
4-hydroxy (S)-Duloxetine β-D-glucuronide is an inactive metabolite of the serotonin and norepinephrine reuptake inhibitor (S)-duloxetine. -
GC42405
4-hydroxy Atorvastatin (calcium salt)
p-hydroxy Atorvastatin, para-hydroxy Atorvastatin
4-hydroxy Atorvastatin is a metabolite of atorvastatin, an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias. -
GC18425
4-hydroxy Atorvastatin lactone
p-hydroxy Atorvastatin lactone, para-hydroxy Atorvastatin lactone
4-hydroxy Atorvastatin lactone is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.
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GC42407
4-hydroxy Diclofenac
4-Hydroxy-Diclofenac ist ein oral aktiver Metabolit von Diclofenac durch Cytochrom P450 2C9 (CYP2C9).
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GC42409
4-hydroxy Nebivolol (hydrochloride)
4-hydroxy Nebivolol is a major metabolite of nebivolol.
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GC49575
4-hydroxy Omeprazole sulfide
4-hydroxy OMEP sulfide, 4-hydroxy OMP sulfide, 4-hydroxy OMZ sulfide
A metabolite of omeprazole -
GC40879
4-hydroxy Solifenacin N-oxide
4-hydroxy Solifenacin N-oxide is an N-oxide form of 4-hydroxy solifenacin, the major metabolite of solifenacin .
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GC42415
4-hydroxy Valsartan
CGP 71580, Valeryl 4-hydroxy Valsartan
4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan. -
GC18417
4-hydroxy Xylazine
p-hydroxy Xylazine, para-hydroxy Xylazine
4-Hydroxy-Xylazin ist ein Metabolit von Xylazin.
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GC90790
4-hydroxy Xylazine O-Glucuronide (lithium salt)
Ein Stoffwechselprodukt von Xylazin.
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GC91641
4-Hydroxy-1-(2-phenylethyl)piperidine
4-Hydroxy-1-(2-phenylethyl)piperidine is a building block that has been used in the synthesis of ligands of the muscarinic acetylcholine receptor (mAChR) or sigma non-opioid intracellular receptor 1 (σ1 receptor).
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GC60517
4-Hydroxyatomoxetine
4-Hydroxyatomoxetin ist ein aktiver Metabolit von Atomoxetin.
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GC39307
4-Methylamino antipyrine
4-Methylamino-Antipyrin ist ein aktiver Metabolit von Metamizol.
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GC60523
4-Methylamino antipyrine hydrochloride
Metamizole Impurity C
4-Methylamino-Antipyrin-Hydrochlorid ist ein aktiver Metabolit von Metamizol. -
GC49127
4-oxo Cyclophosphamide
4-keto CP, 4-keto Cyclophosphamide, NSC 139488, 4-oxo CP
An inactive metabolite of cyclophosphamide -
GC41399
5α-dihydro Levonorgestrel
5α-DHLNG
5α-dihydro Levonorgestrel is a metabolite of the synthetic progestin levonorgestrel. -
GC18582
5'-hydroxy Meloxicam
A metabolite of meloxicam