Mitophagy
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Mitophagy is the selective degradation of mitochondria by autophagy.
Mitochondria are essential organelles that regulate cellular energy homeostasis and cell death. The removal of damaged mitochondria through autophagy, a process called mitophagy, is thus critical for maintaining proper cellular functions. Indeed, mitophagy has been recently proposed to play critical roles in terminal differentiation of red blood cells, paternal mitochondrial degradation, neurodegenerative diseases, and ischemia or drug-induced tissue injury.
Autophagy and mitophagy are important cellular processes that are responsible for breaking down cellular contents, preserving energy and safeguarding against accumulation of damaged and aggregated biomolecules.
Products Related to Mitophagy(84)
- GC74187Salicylic acid-13C6CAS: 1189678-81-6Purity: >97.00%
Salicylic acid-13C6 ist die 13C-markierte Salicylsäure.
- GC80919AURKA-IN-4CAS: 89575-11-1Purity: >99.50%
AURKA-IN-4 is a Capsaicin -derived molecular glue targeting AURKA-PHB2, and acts as an inhibitor of Aurora kinase A ( AURKA ) and PHB2.
- GN10156Ginsenoside Rb1CAS: 41753-43-9Purity: >98.00%
Ginsenoside Rb1 is a natural active ingredient extracted from ginseng that can modulate the activity of multiple signaling pathways.
- GN10357ParthenolideCAS: 20554-84-1Purity: >98.00%
Parthenolide ist ein NF-κB-Inhibitor mit IC 50 -Werten für Eca109-, KYSE-510-, SiHa- und MCF-7-Zellen von ungefähr 10.3, 13.3, 8.42 und 9.54μM nach 48 Stunden.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC71260 | Dox-btn2 | 3026061-31-1 | >97.00% | |
Dox-btn2 ist ein biotinyliertes Derivat von Doxorubicin mit einem Biotin-Label am Punkt der Konjugation zu Doxorubicin bei 3'-NH2. | ||||
| GC71423 | ATTECs Degrader 1 | - | >95.00% | |
ATTECs Degrader 1 (Compound MT1) ist eine ATTEC-Verbindung. | ||||
| GC71451 | MTX115325 | 2750895-97-5 | >99.00% | |
MTX115325 (Beispiel 1) ist ein oral aktiver, hirn-penetrierender USP30-Inhibitor (IC50=12 nM) mit neuroprotektiver Aktivität. | ||||
| GC71492 | WJ-39 | 3009908-95-3 | >99.00% | |
WJ-39 ist ein oral aktiver Aldosereduktase (AR)-Hemmer. | ||||
| GC74187 | Salicylic acid-13C6 | 1189678-81-6 | >97.00% | |
Salicylic acid-13C6 ist die 13C-markierte Salicylsäure. | ||||
| GC80919 | AURKA-IN-4 | 89575-11-1 | >99.50% | |
AURKA-IN-4 is a Capsaicin -derived molecular glue targeting AURKA-PHB2, and acts as an inhibitor of Aurora kinase A ( AURKA ) and PHB2. | ||||
| GC81846 | Nivitol | 869743-37-3 | >98.00% | |
Nivitol (UP302) is a natural phenolic compound discovered from Dianella ensifolia and also acts as a Tyrosinase inhibitor. | ||||
| GN10156 | Ginsenoside Rb1 | 41753-43-9 | >98.00% | |
Ginsenoside Rb1 is a natural active ingredient extracted from ginseng that can modulate the activity of multiple signaling pathways. | ||||
| GN10257 | Naringin | 10236-47-2 | >99.50% | |
| GN10266 | Quercetin | 117-39-5 | >97.00% | |
Quercetin ist ein wichtiger diätetischer Flavonoid, der in Gemüse, Obst, Samen, Nüssen, Tee und Rotwein vorkommt. | ||||
| GN10331 | Polydatin | 27208-80-6 | >98.00% | |
Polydatin is a natural stilbene glucoside extracted from the traditional Chinese medicine Polygonum cuspidatum , and Polydatin is the glycoside form of resveratrol. | ||||
| GN10357 | Parthenolide | 20554-84-1 | >98.00% | |
Parthenolide ist ein NF-κB-Inhibitor mit IC 50 -Werten für Eca109-, KYSE-510-, SiHa- und MCF-7-Zellen von ungefähr 10.3, 13.3, 8.42 und 9.54μM nach 48 Stunden. | ||||