TRITC-dextran, MW 20000 (Tetrametl rhodamine isothiocyanate glucan, MW 20000) is a fluorescent dye, with the molecular weight of 20 kD. TRITC-dextran MW 20000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 20000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 20000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching.
References:
[1]. Tran NBNN, et al., Gradient-dependent release of the model drug TRITC-dextran from FITC-labeled BSA drogel nanocarriers in the hair follicles of porcine ear skin. Eur J Pharm Biopharm. 2017 Jul;116:12-16.
[2]. Kawoos U, et al., N-acetylcysteine Amide Ameliorates Blast-Induced Changes in Blood-Brain Barrier Integrity in Rats. Front Neurol. 2019 Jun 26;10:650.
[3]. Somaratne G, et al., In-situ disintegration of egg white gels by pepsin and kinetics of nutrient release followed by time-lapse confocal microscopy[J]. Food drocolloids, 2020, 98: 105228.